Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ldj | GDP | GTPase KRas |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ldj | GDP | GTPase KRas | / | 1.000 | |
| 4ql3 | GDP | GTPase KRas | / | 0.809 | |
| 4epx | GDP | GTPase KRas | / | 0.782 | |
| 4q03 | GDP | GTPase KRas | / | 0.759 | |
| 4q02 | GDP | GTPase KRas | / | 0.643 | |
| 4tq9 | GDP | GTPase KRas | / | 0.613 | |
| 4lpk | GDP | GTPase KRas | / | 0.612 | |
| 4l8g | GDP | GTPase KRas | / | 0.607 | |
| 3kkq | GDP | Ras-related protein M-Ras | / | 0.600 | |
| 4obe | GDP | GTPase KRas | / | 0.591 | |
| 4epw | GDP | GTPase KRas | / | 0.582 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.582 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.580 | |
| 4lv6 | GDP | GTPase KRas | / | 0.578 | |
| 2rgg | GNP | GTPase HRas | / | 0.576 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.575 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.574 | |
| 4l9s | GDP | GTPase HRas | / | 0.574 | |
| 4wa7 | GDP | GTPase KRas | / | 0.572 | |
| 4dsu | GDP | GTPase KRas | / | 0.560 | |
| 3k9l | GNP | GTPase HRas | / | 0.556 | |
| 4lrw | GDP | GTPase KRas | / | 0.552 | |
| 3ddc | GNP | GTPase HRas | / | 0.550 | |
| 3rs5 | GNP | GTPase HRas | / | 0.549 | |
| 2rgb | GNP | GTPase HRas | / | 0.548 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.548 | |
| 4xvq | GNP | GTPase HRas | / | 0.548 | |
| 3i3s | GNP | GTPase HRas | / | 0.547 | |
| 2ce2 | GDP | GTPase HRas | / | 0.541 | |
| 4dlt | GNP | GTPase HRas | / | 0.541 | |
| 3lbh | GNP | GTPase HRas | / | 0.540 | |
| 3oiv | GNP | GTPase HRas | / | 0.538 | |
| 3rsl | GNP | GTPase HRas | / | 0.538 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.538 | |
| 2c5l | GTP | GTPase HRas | / | 0.537 | |
| 3tgp | GNP | GTPase HRas | / | 0.537 | |
| 3rs4 | GNP | GTPase HRas | / | 0.532 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.532 | |
| 4dsn | GCP | GTPase KRas | / | 0.532 | |
| 4g0n | GNP | GTPase HRas | / | 0.532 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.531 | |
| 4dlx | GNP | GTPase HRas | / | 0.531 | |
| 4xvr | GNP | GTPase HRas | / | 0.531 | |
| 2bme | GNP | Ras-related protein Rab-4A | / | 0.529 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.528 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.528 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.528 | |
| 3l8y | GNP | GTPase HRas | / | 0.526 | |
| 4dlv | GNP | GTPase HRas | / | 0.526 | |
| 5dif | GNP | GTP-binding nuclear protein Ran | / | 0.525 | |
| 3v4f | GNP | GTPase HRas | / | 0.524 | |
| 3rs0 | GNP | GTPase HRas | / | 0.523 | |
| 2rgc | GNP | GTPase HRas | / | 0.522 | |
| 1d5c | GDP | GTPase (Rab6) | / | 0.520 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.520 | |
| 2msc | GDP | MHC class I alpha chain | / | 0.519 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.519 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.518 | |
| 4dlz | GNP | GTPase HRas | / | 0.517 | |
| 4dlw | GNP | GTPase HRas | / | 0.516 | |
| 3oiu | GNP | GTPase HRas | / | 0.515 | |
| 3lbi | GNP | GTPase HRas | / | 0.513 | |
| 5b2z | GNP | GTPase HRas | / | 0.513 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.512 | |
| 3kud | GDP | GTPase HRas | / | 0.512 | |
| 2oo7 | AP5 | Adenylate kinase | / | 0.510 | |
| 4nyj | GNP | GTPase HRas | / | 0.510 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.509 | |
| 1z2a | GDP | Ras-related protein Rab-23 | / | 0.508 | |
| 2rge | GNP | GTPase HRas | / | 0.507 | |
| 3lbn | GNP | GTPase HRas | / | 0.507 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.506 | |
| 3oiw | GNP | GTPase HRas | / | 0.506 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.505 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.504 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.503 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.501 | |
| 3rs7 | GNP | GTPase HRas | / | 0.501 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.501 | |
| 1lfd | GNP | GTPase HRas | / | 0.499 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.499 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.498 | |
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 0.498 | |
| 3x1w | GDP | Ras-related protein Rap-1b | / | 0.498 | |
| 4dls | GNP | GTPase HRas | / | 0.498 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.495 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.494 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.494 | |
| 3k8y | GNP | GTPase HRas | / | 0.494 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.494 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.494 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.493 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.492 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 1e0j | ANP | DNA primase/helicase | 2.7.7 | 0.490 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.489 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.489 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.489 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.489 | |
| 4dso | GSP | GTPase KRas | / | 0.488 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.488 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.486 | |
| 1g16 | GDP | Ras-related protein SEC4 | / | 0.484 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.484 | |
| 4nyi | GNP | GTPase HRas | / | 0.484 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.482 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 4l9w | GNP | GTPase HRas | / | 0.482 | |
| 3vhx | GTP | ADP-ribosylation factor 6 | / | 0.481 | |
| 2msd | GNP | MHC class I alpha chain | / | 0.479 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.479 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.479 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.479 | |
| 4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.479 | |
| 1a4r | GNH | Cell division control protein 42 homolog | / | 0.478 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.478 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.478 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.477 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.476 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.476 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.476 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.474 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.474 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.473 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.473 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.473 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.473 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.472 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.472 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.472 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.471 | |
| 2cl6 | CAG | GTPase HRas | / | 0.471 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.471 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.471 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.471 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.470 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.470 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.470 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.470 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.470 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.470 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.469 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.469 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.469 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.468 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.467 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.467 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
| 4lb2 | DM5 | Serum albumin | / | 0.467 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.467 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.467 | |
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.466 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.466 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.466 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.466 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.466 | |
| 4l8u | 9AZ | Serum albumin | / | 0.466 | |
| 1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.465 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.465 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.465 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.465 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.465 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.465 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.465 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.464 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.464 | |
| 2i62 | SAH | Nicotinamide N-methyltransferase | 2.1.1.1 | 0.464 | |
| 3eku | CY9 | Actin-5C | / | 0.464 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.463 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.463 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.463 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.463 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.463 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.462 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.462 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.462 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.462 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.462 | |
| 3ry2 | BTN | Streptavidin | / | 0.462 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.462 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.461 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.461 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2l0x | GDP | GTP-binding protein Rheb | / | 0.461 | |
| 2wbg | LGS | Beta-glucosidase A | 3.2.1.21 | 0.461 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.461 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.461 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.461 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.461 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.460 | |
| 1q4w | DQU | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.460 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.460 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.460 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 1am4 | GNP | Cell division control protein 42 homolog | / | 0.459 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.459 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.459 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.459 | |
| 3hpq | AP5 | Adenylate kinase | / | 0.459 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.459 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.458 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4f31 | KAI | Glutamate receptor 3 | / | 0.458 | |
| 4h6u | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.458 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.458 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.458 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.458 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.457 | |
| 2bxq | IMN | Serum albumin | / | 0.457 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.457 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.457 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.457 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.457 | |
| 3uq9 | TBN | Putative adenosine kinase | / | 0.457 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.457 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.457 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.457 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.457 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.456 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.456 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.456 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.456 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.456 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.456 | |
| 4krs | 1SX | Tankyrase-1 | 2.4.2.30 | 0.456 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.456 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.455 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4ap0 | ADP | Kinesin-like protein KIF11 | / | 0.455 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.455 | |
| 5iqa | GNP | Bifunctional AAC/APH | 2.3.1 | 0.455 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.454 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.454 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.454 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.454 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.454 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4m0l | GDP | Translation initiation factor 2 subunit gamma | / | 0.454 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.454 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.454 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.453 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.453 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.453 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.453 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3b78 | NAD | Exotoxin A | 2.4.2.36 | 0.453 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3uel | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.453 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.453 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.453 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4loh | 1SY | Stimulator of interferon genes protein | / | 0.453 | |
| 4mit | GTP | Rho-related protein racC | / | 0.453 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.452 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.452 | |
| 2az3 | CDP | Nucleoside diphosphate kinase | / | 0.452 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.452 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.452 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.452 | |
| 3pt9 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.452 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.452 | |
| 4b0q | GMF | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.452 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.452 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.451 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.451 | |
| 1mra | APG | Mandelate racemase | / | 0.451 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.451 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.451 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.451 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.451 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.451 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.451 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.451 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.451 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.451 | |
| 3dkv | AP5 | Adenylate kinase | / | 0.451 | |
| 4dc3 | 2FA | Putative adenosine kinase | / | 0.451 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.451 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.451 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.451 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.451 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1zdw | FLV | Prenyltransferase | / | 0.450 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2bxm | IMN | Serum albumin | / | 0.450 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.450 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.450 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 3fmo | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 | 0.450 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.450 | |
| 3v2b | AR6 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.450 | |
| 3wyf | GTP | GTP-binding nuclear protein | / | 0.450 | |
| 4qbi | AP5 | Adenylate kinase | / | 0.450 | |
| 5il1 | SAM | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.450 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.449 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.449 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.449 | |
| 2izh | BTN | Streptavidin | / | 0.449 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.449 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.449 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3gb4 | D3M | DdmC | / | 0.449 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.449 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.449 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.449 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.449 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.449 | |
| 4z28 | BTN | Hoefavidin | / | 0.449 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.448 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.448 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 1v8k | ANP | Kinesin-like protein KIF2C | / | 0.448 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.448 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.448 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1syn | F89 | Thymidylate synthase | / | 0.447 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.447 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.447 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.447 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.447 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.447 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.447 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.447 | |
| 2v34 | CTN | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 3cwk | REA | Cellular retinoic acid-binding protein 2 | / | 0.447 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.447 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 4ap3 | NAP | Steroid monooxygenase | / | 0.447 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4e2y | JHZ | Methyltransferase | / | 0.447 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.447 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.447 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.447 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.446 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.446 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.446 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.446 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.446 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.446 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.446 | |
| 2rtk | GLL | Streptavidin | / | 0.446 | |
| 2wlg | SOP | Polysialic acid O-acetyltransferase | / | 0.446 | |
| 2y66 | N04 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.446 | |
| 3mpe | N2A | Cathepsin S | 3.4.22.27 | 0.446 | |
| 3rga | ILD | Epoxide hydrolase LasB | 5.5.1 | 0.446 | |
| 3sfd | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.446 | |
| 3up0 | D7S | aceDAF-12 | / | 0.446 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.446 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.446 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.446 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1b8n | IMG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.445 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.445 | |
| 1tsl | A15 | Thymidylate synthase | / | 0.445 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.445 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.445 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.445 | |
| 3wag | TYD | Glycosyltransferase | / | 0.445 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.445 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.445 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1id0 | ANP | Sensor protein PhoQ | 2.7.13.3 | 0.444 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.444 | |
| 1s4e | ADP | Galactokinase | / | 0.444 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.444 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.444 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.444 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.444 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2izf | BTN | Streptavidin | / | 0.444 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.444 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3gts | D3M | DdmC | / | 0.444 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.444 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.444 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.444 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.444 | |
| 4gzl | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.444 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.444 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.444 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.444 | |
| 1cde | DZF | Phosphoribosylglycinamide formyltransferase | / | 0.443 | |
| 1ii6 | ADP | Kinesin-like protein KIF11 | / | 0.443 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.443 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.443 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.443 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.443 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.443 | |
| 2izk | GLL | Streptavidin | / | 0.443 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.443 | |
| 2wlf | ACO | Polysialic acid O-acetyltransferase | / | 0.443 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.443 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.443 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.443 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.443 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.443 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.443 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.442 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.442 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1mf0 | GDP | Adenylosuccinate synthetase isozyme 1 | / | 0.442 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 1xjj | DGT | Vitamin B12-dependent ribonucleotide reductase | / | 0.442 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.442 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.442 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.442 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2mse | GNP | MHC class I alpha chain | / | 0.442 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2q3f | GNP | Ras-related GTP-binding protein D | / | 0.442 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.442 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.442 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.442 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.442 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.442 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4h5c | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.442 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.442 | |
| 4mkg | AP5 | Adenylate kinase | / | 0.442 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.442 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.441 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.441 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.441 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.441 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.441 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4hmx | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.441 | |
| 4k38 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.441 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.441 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.440 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.440 | |
| 1lwx | AZD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.440 | |
| 1n2b | PAF | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.440 | |
| 1szc | CNA | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.440 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 2amb | 17H | Androgen receptor | / | 0.440 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.440 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3t3i | GPW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3up3 | XCA | aceDAF-12 | / | 0.440 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.440 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4dem | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.440 | |
| 4dij | BLF | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.440 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 0.440 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.440 |