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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4kwi1TJReductase homolog

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4kwi1TJReductase homolog/1.000
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1k6cMK1Gag-Pol polyprotein3.4.23.160.446
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2gjnFMNNitronate monooxygenase1.13.12.160.443
2po7CHDFerrochelatase, mitochondrial4.99.1.10.440
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440