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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.10

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.101.000
4qmpDKISerine/threonine-protein kinase 242.7.11.10.545
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.540
3rak03ZCyclin-dependent kinase 22.7.11.220.533
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.533
4dgo0JWCasein kinase II subunit alpha2.7.11.10.533
4dgnLU2Casein kinase II subunit alpha2.7.11.10.529
3zep1NXTyrosine-protein kinase JAK32.7.10.20.524
2pvnP63Casein kinase II subunit alpha2.7.11.10.522
3be9P04Casein kinase II subunit alpha2.7.11.10.521
4anmWULCasein kinase II subunit alpha2.7.11.10.521
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.520
4fko20KCyclin-dependent kinase 22.7.11.220.519
3zh8C58Protein kinase C iota type2.7.11.130.517
4bgg844Activin receptor type-12.7.11.300.517
3ezvEZVCyclin-dependent kinase 22.7.11.220.516
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.515
3rmf20ZCyclin-dependent kinase 22.7.11.220.515
3sw719KCyclin-dependent kinase 22.7.11.220.515
1di8DTQCyclin-dependent kinase 22.7.11.220.514
2pvhP19Casein kinase II subunit alpha2.7.11.10.514
1urwI1PCyclin-dependent kinase 22.7.11.220.512
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.512
3s1h56ZCyclin-dependent kinase 22.7.11.220.512
1gih1PUCyclin-dependent kinase 22.7.11.220.511
2w05FRTCyclin-dependent kinase 22.7.11.220.511
3uli1N3Cyclin-dependent kinase 22.7.11.220.511
2vv9IM9Cyclin-dependent kinase 22.7.11.220.510
3rpv26ZCyclin-dependent kinase 22.7.11.220.510
1gij2PUCyclin-dependent kinase 22.7.11.220.509
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.509
1om1IQACasein kinase II subunit alpha2.7.11.10.506
3ggfGVDSerine/threonine-protein kinase 26/0.506
2xmyCDKCyclin-dependent kinase 22.7.11.220.505
4fkv61KCyclin-dependent kinase 22.7.11.220.505
1m2pHNACasein kinase II subunit alpha2.7.11.10.504
3gxlQIGTGF-beta receptor type-12.7.11.300.504
3qtuX44Cyclin-dependent kinase 22.7.11.220.504
4acm7YGCyclin-dependent kinase 22.7.11.220.503
4erwSTUCyclin-dependent kinase 22.7.11.220.503
1g5sI17Cyclin-dependent kinase 22.7.11.220.502
5e8wSTUTGF-beta receptor type-12.7.11.300.502
2xikJ60Serine/threonine-protein kinase 252.7.11.10.500
3ral04ZCyclin-dependent kinase 22.7.11.220.500
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.500
3unk0BYCyclin-dependent kinase 22.7.11.220.500
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.499
2w17I19Cyclin-dependent kinase 22.7.11.220.499
4bbfO19Tyrosine-protein kinase JAK2/0.498
4gmy0X5Tyrosine-protein kinase JAK2/0.498
1xjdSTUProtein kinase C theta type2.7.11.130.497
1y91CT9Cyclin-dependent kinase 22.7.11.220.497
3mtfA3FActivin receptor type-12.7.11.300.497
4bgh3I6Cyclin-dependent kinase 22.7.11.220.497
4hge15VTyrosine-protein kinase JAK2/0.497
4jr7GNPCasein kinase II subunit alpha2.7.11.10.497
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.496
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.496
4fkt48KCyclin-dependent kinase 22.7.11.220.496
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.496
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.496
1fvv107Cyclin-dependent kinase 22.7.11.220.495
3at4CCKCasein kinase II subunit alpha2.7.11.10.495
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.494
1ke6LS2Cyclin-dependent kinase 22.7.11.220.493
1m2rMNYCasein kinase II subunit alpha2.7.11.10.493
3rk708ZCyclin-dependent kinase 22.7.11.220.493
4dymIYZActivin receptor type-12.7.11.300.493
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.493
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.492
3qtxX43Cyclin-dependent kinase 22.7.11.220.492
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.492
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.492
1oi9N20Cyclin-dependent kinase 22.7.11.220.491
3ortAGSSerine/threonine protein kinase/0.491
3rni21ZCyclin-dependent kinase 22.7.11.220.491
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.491
1pyePM1Cyclin-dependent kinase 22.7.11.220.490
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.490
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.490
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.490
2pvlP55Casein kinase II subunit alpha2.7.11.10.489
3r9oZ71Cyclin-dependent kinase 22.7.11.220.489
3sw418KCyclin-dependent kinase 22.7.11.220.489
4fks46KCyclin-dependent kinase 22.7.11.220.489
3oroAGSSerine/threonine protein kinase/0.488
3py0SU9Cyclin-dependent kinase 22.7.11.220.488
2btsU32Cyclin-dependent kinase 22.7.11.220.487
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.487
3r9dX6BCyclin-dependent kinase 22.7.11.220.487
3rk507ZCyclin-dependent kinase 22.7.11.220.487
3rpy27ZCyclin-dependent kinase 22.7.11.220.487
4g170VNCasein kinase I isoform gamma-32.7.11.10.487
4hvi19STyrosine-protein kinase JAK32.7.10.20.487
5auwQUEDeath-associated protein kinase 12.7.11.10.487
5av2KMPDeath-associated protein kinase 12.7.11.10.487
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.485
2hog710Serine/threonine-protein kinase Chk12.7.11.10.485
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.485
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.485
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.484
2z2w770Wee1-like protein kinase2.7.10.20.484
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.484
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.484
2iw84SPCyclin-dependent kinase 22.7.11.220.483
3unj0BXCyclin-dependent kinase 22.7.11.220.483
1pxoCK7Cyclin-dependent kinase 22.7.11.220.482
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.482
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.482
4jia1K3Tyrosine-protein kinase JAK2/0.482
1h1s4SPCyclin-dependent kinase 22.7.11.220.481
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.481
2btrU73Cyclin-dependent kinase 22.7.11.220.481
2cchATPCyclin-dependent kinase 22.7.11.220.481
3gubGUBDeath-associated protein kinase 12.7.11.10.481
3uzp0CKCasein kinase I isoform delta2.7.11.10.481
4f081RSTyrosine-protein kinase JAK2/0.481
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.481
4qmzB49Serine/threonine-protein kinase 242.7.11.10.481
5auvAGIDeath-associated protein kinase 12.7.11.10.481
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.480
5av4GENDeath-associated protein kinase 12.7.11.10.480
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.479
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.479
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.479
4fkw62KCyclin-dependent kinase 22.7.11.220.479
1gii1PUCyclin-dependent kinase 22.7.11.220.478
1ke5LS1Cyclin-dependent kinase 22.7.11.220.478
1vjy460TGF-beta receptor type-12.7.11.300.478
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.478
3iok1P6Tyrosine-protein kinase JAK2/0.478
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.478
4aqc88ATyrosine-protein kinase JAK2/0.478
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.478
1e9hINRCyclin-dependent kinase 22.7.11.220.477
1h1r6CPCyclin-dependent kinase 22.7.11.220.477
1oiqHDUCyclin-dependent kinase 22.7.11.220.477
2h96893Mitogen-activated protein kinase 82.7.11.240.477
4ez50RSCyclin-dependent kinase 62.7.11.220.477
2eufLQQCyclin-dependent kinase 62.7.11.220.476
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.476
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
4grb0XGCasein kinase II subunit alpha2.7.11.10.476
3qxpX64Cyclin-dependent kinase 22.7.11.220.475
4ivb1J5Tyrosine-protein kinase JAK1/0.475
1p2a5BNCyclin-dependent kinase 22.7.11.220.474
2xa4AZ5Tyrosine-protein kinase JAK2/0.474
3a60STURibosomal protein S6 kinase beta-12.7.11.10.474
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.474
3qtzX42Cyclin-dependent kinase 22.7.11.220.474
4fkg4CKCyclin-dependent kinase 22.7.11.220.474
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.474
3lfqA28Cyclin-dependent kinase 22.7.11.220.473
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.473
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.473
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.473
2w1hL0FCyclin-dependent kinase 22.7.11.220.472
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.472
4dgmAGICasein kinase II subunit alpha2.7.11.10.472
4e6d0NUTyrosine-protein kinase JAK2/0.472
1aq1STUCyclin-dependent kinase 22.7.11.220.471
1pxmCK5Cyclin-dependent kinase 22.7.11.220.471
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.471
2uzoC62Cyclin-dependent kinase 22.7.11.220.471
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.471
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.471
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.471
4jqeANPCasein kinase II subunit alpha2.7.11.10.471
3lltANPProtein serine/threonine kinase-1/0.470
3qu0X40Cyclin-dependent kinase 22.7.11.220.470
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.470
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.470
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.470
1pkdUCNCyclin-dependent kinase 22.7.11.220.469
1w0xOLOCyclin-dependent kinase 22.7.11.220.469
3rk909ZCyclin-dependent kinase 22.7.11.220.469
4c62XWWTyrosine-protein kinase JAK2/0.469
1rw8580TGF-beta receptor type-12.7.11.300.468
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.468
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.468
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.468
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.468
5auxKMPDeath-associated protein kinase 12.7.11.10.468
2wotZZGTGF-beta receptor type-12.7.11.300.467
2wouZZFTGF-beta receptor type-12.7.11.300.467
4c61LMMTyrosine-protein kinase JAK2/0.467
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.467
4iwd1JCHepatocyte growth factor receptor2.7.10.10.467
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.467
5dr9SKEAurora kinase A2.7.11.10.467
2b52D42Cyclin-dependent kinase 22.7.11.220.466
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.466
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.466
3q9xEMOCasein kinase II subunit alpha2.7.11.10.466
2j9mPY8Cyclin-dependent kinase 22.7.11.220.465
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.465
3r8lZ30Cyclin-dependent kinase 22.7.11.220.465
3zewSTUEphrin type-B receptor 42.7.10.10.465
4fkq42KCyclin-dependent kinase 22.7.11.220.465
4qmySTUSerine/threonine-protein kinase 242.7.11.10.465
1py5PY1TGF-beta receptor type-12.7.11.300.464
1ykr628Cyclin-dependent kinase 22.7.11.220.464
1yvj4STTyrosine-protein kinase JAK32.7.10.20.464
2c6tDT5Cyclin-dependent kinase 22.7.11.220.464
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.464
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4hvh19RTyrosine-protein kinase JAK32.7.10.20.464
4qnaX11Serine/threonine-protein kinase 242.7.11.10.464
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.464
3axwTIDCasein kinase II subunit alpha2.7.11.10.463
3ormAGSSerine/threonine protein kinase/0.463
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.463
4hgs15GCasein kinase I isoform gamma-32.7.11.10.463
1oiuN76Cyclin-dependent kinase 22.7.11.220.462
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.462
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.462
2uzdC85Cyclin-dependent kinase 22.7.11.220.462
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.462
3rkb12ZCyclin-dependent kinase 22.7.11.220.462
3sheI85MAP kinase-activated protein kinase 32.7.11.10.462
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
4ek816KCyclin-dependent kinase 22.7.11.220.462
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.462
1h0w207Cyclin-dependent kinase 22.7.11.220.461
1oguST8Cyclin-dependent kinase 22.7.11.220.461
2in6839Wee1-like protein kinase2.7.10.20.461
2xnbY8LCyclin-dependent kinase 22.7.11.220.461
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.461
4ehzJAKTyrosine-protein kinase JAK1/0.461
4fx360KCyclin-dependent kinase 22.7.11.220.461
4g160VMCasein kinase I isoform gamma-32.7.11.10.461
1ke7LS3Cyclin-dependent kinase 22.7.11.220.460
1wvxBD4Death-associated protein kinase 12.7.11.10.460
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.460
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.460
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.460
4e4m0NHTyrosine-protein kinase JAK2/0.460
4ivc1J6Tyrosine-protein kinase JAK1/0.460
4jboWPHAurora kinase A2.7.11.10.460
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.460
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.459
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.459
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.459
2c6iDT1Cyclin-dependent kinase 22.7.11.220.459
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.459
2vttLZDCyclin-dependent kinase 22.7.11.220.459
2vu3LZECyclin-dependent kinase 22.7.11.220.459
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.459
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.459
3nwxKVSGag-Pol polyprotein3.4.23.160.459
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.459
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.459
4nj32KDCyclin-dependent kinase 22.7.11.220.459
2c5yMTWCyclin-dependent kinase 22.7.11.220.458
2ckeIQUDeath-associated protein kinase 2/0.458
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.458
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.458
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.458
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.458
1ke9LS5Cyclin-dependent kinase 22.7.11.220.457
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.457
2izsBRQCasein kinase I isoform gamma-32.7.11.10.457
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.457
2pmoHMDProtein kinase 7/0.457
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.457
3lfnA27Cyclin-dependent kinase 22.7.11.220.457
2c6o4SPCyclin-dependent kinase 22.7.11.220.456
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.456
2w06FRVCyclin-dependent kinase 22.7.11.220.456
3hmm855TGF-beta receptor type-12.7.11.300.456
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.456
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.456
4yswFADXanthine dehydrogenase/oxidase/0.456
1oitHDTCyclin-dependent kinase 22.7.11.220.455
2bheBRYCyclin-dependent kinase 22.7.11.220.455
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3lpbNVBTyrosine-protein kinase JAK2/0.455
3oom507Activin receptor type-12.7.11.300.455
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.455
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.455
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.455
1pxlCK4Cyclin-dependent kinase 22.7.11.220.454
2wihP48Cyclin-dependent kinase 22.7.11.220.454
3bu5ATPInsulin receptor2.7.10.10.454
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.454
3eb0DRKUncharacterized protein/0.454
3nynSGVG protein-coupled receptor kinase 62.7.11.160.454
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.454
3qzhX69Cyclin-dependent kinase 22.7.11.220.454
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.454
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.454
4ez30S0Cyclin-dependent kinase 22.7.11.220.454
4hvg19QTyrosine-protein kinase JAK32.7.10.20.454
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.454
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.454
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.453
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.453
1oiyN41Cyclin-dependent kinase 22.7.11.220.453
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.453
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.453
3r1yX76Cyclin-dependent kinase 22.7.11.220.453
3r9hZ67Cyclin-dependent kinase 22.7.11.220.453
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.453
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.453
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.453
4ji91M3Tyrosine-protein kinase JAK2/0.453
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.453
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.453
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.452
2iw94SPCyclin-dependent kinase 22.7.11.220.452
3rvg17PTyrosine-protein kinase JAK2/0.452
3s2pPMUCyclin-dependent kinase 22.7.11.220.452
3w33W19Epidermal growth factor receptor2.7.10.10.452
4eok4SPCyclin-dependent kinase 22.7.11.220.452
4fkr45KCyclin-dependent kinase 22.7.11.220.452
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.452
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
4lyn1YGCyclin-dependent kinase 22.7.11.220.452
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.452
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.451
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.451
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.451
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.451
4fki09KCyclin-dependent kinase 22.7.11.220.451
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.451
5ax35IDMitogen-activated protein kinase 12.7.11.240.451
5dr6SKEAurora kinase A2.7.11.10.451
5e8ySTUTGF-beta receptor type-22.7.11.300.451
1jklANPDeath-associated protein kinase 12.7.11.10.450
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.450
2b7aIZATyrosine-protein kinase JAK2/0.450
2izuP01Casein kinase I isoform gamma-32.7.11.10.450
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.450
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.450
3pxyJWSCyclin-dependent kinase 22.7.11.220.450
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.450
4btjATPTau-tubulin kinase 12.7.11.10.450
4ei40Q2Tyrosine-protein kinase JAK1/0.450
4ivd15TTyrosine-protein kinase JAK1/0.450
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.449
2bhhRYUCyclin-dependent kinase 22.7.11.220.449
2x1nX1NCyclin-dependent kinase 22.7.11.220.449
3biz61EWee1-like protein kinase2.7.10.20.449
3sqq99ZCyclin-dependent kinase 22.7.11.220.449
3tnwF18Cyclin-dependent kinase 22.7.11.220.449
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.449
4e4n0NLTyrosine-protein kinase JAK1/0.449
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4fk60UJTyrosine-protein kinase JAK1/0.449
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.449
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.448
3nux3NVCyclin-dependent kinase 62.7.11.220.448
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3ttjJBIMitogen-activated protein kinase 102.7.11.240.448
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.448
4ocvANPAminoglycoside phosphotransferase/0.448
4wsqKSAAP2-associated protein kinase 12.7.11.10.448
5drdATPAurora kinase A2.7.11.10.448
1rfuADPPyridoxal kinase2.7.1.350.447
1v1k3FPCyclin-dependent kinase 22.7.11.220.447
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.447
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.447
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.447
3toh079Gag-Pol polyprotein2.7.7.490.447
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.447
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
2excJNKMitogen-activated protein kinase 102.7.11.240.446
2vtqLZACyclin-dependent kinase 22.7.11.220.446
3bhtMFRCyclin-dependent kinase 22.7.11.220.446
3qzgX67Cyclin-dependent kinase 22.7.11.220.446
3ti1B49Cyclin-dependent kinase 22.7.11.220.446
3zdu38RCyclin-dependent kinase-like 32.7.11.220.446
4y93746Tyrosine-protein kinase/0.446
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.446
1p4fDRGDeath-associated protein kinase 12.7.11.10.445
2a0cCK9Cyclin-dependent kinase 22.7.11.220.445
2c6lDT4Cyclin-dependent kinase 22.7.11.220.445
3at3ATKCasein kinase II subunit alpha2.7.11.10.445
3cgfJNFMitogen-activated protein kinase 102.7.11.240.445
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.445
3l8p0CEAngiopoietin-1 receptor2.7.10.10.445
3qtqX35Cyclin-dependent kinase 22.7.11.220.445
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.444
2j0m4STFocal adhesion kinase 12.7.10.20.444
2r3jSCJCyclin-dependent kinase 22.7.11.220.444
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.444
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.444
3qqkX02Cyclin-dependent kinase 22.7.11.220.444
3roy22ZCyclin-dependent kinase 22.7.11.220.444
3u4uLNHCasein kinase II subunit alpha2.7.11.10.444
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.444
4ii5ADPCyclin-dependent kinase 22.7.11.220.444
4xlvACPInsulin receptor2.7.10.10.444
1hiiC20Gag-Pol polyprotein/0.443
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.443
2x4f16XMyosin light chain kinase family member 42.7.11.10.443
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.443
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.443
4jajXU1Aurora kinase A2.7.11.10.443
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.443
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
1u4dDBQActivated CDC42 kinase 1/0.442
2r3iSCFCyclin-dependent kinase 22.7.11.220.442
2r3lSCWCyclin-dependent kinase 22.7.11.220.442
3bi6396Wee1-like protein kinase2.7.10.20.442
3livE16Protease/0.442
3rjc06ZCyclin-dependent kinase 22.7.11.220.442
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.442
4jbpYPHAurora kinase A2.7.11.10.442
4utdACPAurora kinase A2.7.11.10.442
1eh4IC1Casein kinase I homolog 12.7.11.10.441
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.441
1x8b824Wee1-like protein kinase2.7.10.20.441
2chlDKICasein kinase I isoform gamma-32.7.11.10.441
2dwbANPAurora kinase A2.7.11.10.441
2izrBRKCasein kinase I isoform gamma-32.7.11.10.441
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.441
3gu6ADPDeath-associated protein kinase 12.7.11.10.441
3qxoX65Cyclin-dependent kinase 22.7.11.220.441
4i22IREEpidermal growth factor receptor2.7.10.10.441
1pxpCK8Cyclin-dependent kinase 22.7.11.220.440
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.440
2j0j4STFocal adhesion kinase 12.7.10.20.440
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.440
2z97CAMCamphor 5-monooxygenase1.14.15.10.440
3du8553Glycogen synthase kinase-3 beta2.7.11.260.440
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.440
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.440
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.440
3zmmF9JTyrosine-protein kinase JAK2/0.440
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.440
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4j95ACPFibroblast growth factor receptor 2/0.440