sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4khn | XG4 | DNA-directed DNA polymerase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4khn | XG4 | DNA-directed DNA polymerase | / | 1.000 | |
| 1clq | GDP | DNA-directed DNA polymerase | / | 0.520 | |
| 4i9q | XG4 | DNA-directed DNA polymerase | / | 0.507 | |
| 1waj | 5GP | DNA-directed DNA polymerase | / | 0.485 | |
| 3cfo | GMP | DNA-directed DNA polymerase | / | 0.474 | |
| 4h6p | FMN | Chromate reductase | / | 0.454 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.451 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.448 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.447 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.443 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.442 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.442 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.442 |