sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4kfb | 1QP | Gag-Pol polyprotein | 2.7.7.49 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4kfb | 1QP | Gag-Pol polyprotein | 2.7.7.49 | 1.000 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.508 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.506 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.501 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.496 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.494 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.489 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.485 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.484 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.482 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.481 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.480 | |
| 2dwp | ACP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.480 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.479 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.479 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.479 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.479 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.478 | |
| 3stx | BKA | Methylketone synthase I | / | 0.476 | |
| 4iah | 1DX | Alr2278 protein | / | 0.476 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.475 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.475 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.475 | |
| 3ez2 | ADP | Plasmid partition protein A | / | 0.474 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.474 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.473 | |
| 3gds | VAL_TYR_TYR_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.473 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.473 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.473 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.473 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.471 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.471 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.471 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.470 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.470 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 3zuy | TCH | Transporter | / | 0.470 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 4oae | CLM | Uncharacterized protein | / | 0.470 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.470 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.469 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.469 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.469 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.469 | |
| 4brx | KGW | Focal adhesion kinase 1 | 2.7.10.2 | 0.469 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.469 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.468 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.468 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.468 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.468 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.468 | |
| 4l4x | NDP | AmphI | / | 0.468 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.468 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.467 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.467 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.467 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.467 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.466 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.466 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.466 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.466 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.466 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 5cvc | PLP | Serine racemase | / | 0.466 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.465 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.465 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.465 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.465 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.465 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.465 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.464 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 1ppj | ANY | Cytochrome b | / | 0.463 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.463 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.463 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.463 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.463 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.463 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.463 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 5eg3 | ACP | Fibroblast growth factor receptor 2 | / | 0.463 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.462 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.462 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.462 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.462 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.461 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.461 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.461 | |
| 4pd6 | URI | Nucleoside permease | / | 0.461 | |
| 2nyu | SAM | rRNA methyltransferase 2, mitochondrial | / | 0.460 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.460 | |
| 1gqt | ACP | Ribokinase | / | 0.459 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.459 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.459 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.459 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.459 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.458 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.458 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.458 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.458 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.458 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.458 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.458 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.457 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.457 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.456 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.456 | |
| 3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.456 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.456 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.456 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.456 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.455 | |
| 1q4t | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.455 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.455 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.455 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.455 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.455 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.455 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 4wlo | NAI | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.455 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.455 | |
| 5cds | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.455 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.454 | |
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.454 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.454 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.454 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.454 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.454 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 4b42 | 942 | Glucose-1-phosphate thymidylyltransferase | / | 0.454 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.454 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.454 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.454 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.453 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.453 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.453 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.453 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.453 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.453 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.453 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.453 | |
| 4utd | ACP | Aurora kinase A | 2.7.11.1 | 0.453 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.453 | |
| 1eio | GCH | Gastrotropin | / | 0.452 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.452 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.452 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.452 | |
| 2zgy | GDP | Plasmid segregation protein ParM | / | 0.452 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.452 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.452 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.452 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.451 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.451 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.451 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.451 | |
| 2kce | D16 | Thymidylate synthase | / | 0.451 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.451 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.451 | |
| 3hv5 | R24 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.451 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.451 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.451 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.451 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.451 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.451 | |
| 4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.451 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.450 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.450 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.450 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.450 | |
| 2dbr | NAP | Glyoxylate reductase | 1.1.1.26 | 0.450 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.450 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.450 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.450 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3gye | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.450 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.450 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.450 | |
| 4xx0 | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.450 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1rkd | ADP | Ribokinase | / | 0.449 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.449 | |
| 3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.449 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.449 | |
| 3mwu | BK3 | Calmodulin-domain protein kinase 1, putative | / | 0.449 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.449 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.449 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.449 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.449 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.449 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.448 | |
| 1r6w | 164 | o-succinylbenzoate synthase | / | 0.448 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.448 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.448 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.448 | |
| 3p0j | TYE | Putative tyrosyl-tRNA synthetase | / | 0.448 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.448 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.448 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.448 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.447 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.447 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.447 | |
| 3eya | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.447 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.447 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.447 | |
| 3zm4 | 22T | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.447 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.447 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.446 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.446 | |
| 1z2i | NAD | Putative malate dehydrogenase | / | 0.446 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.446 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.446 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.446 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.446 | |
| 2jkk | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.446 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.446 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.446 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
| 3mfu | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
| 3v8t | 477 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4fsu | HK5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.446 | |
| 1ec3 | MS3 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.445 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.445 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.445 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2pan | FAD | Glyoxylate carboligase | 4.1.1.47 | 0.445 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3f47 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.445 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.445 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.445 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 4fkp | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.445 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.445 | |
| 4mf1 | 29Y | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.445 | |
| 4mle | VO1 | Glucokinase | 2.7.1.2 | 0.445 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.445 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.445 | |
| 4rw4 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 1chw | HXC | Chalcone synthase 2 | 2.3.1.74 | 0.444 | |
| 1het | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.444 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.444 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.444 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2f02 | ATP | Tagatose-6-phosphate kinase | / | 0.444 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.444 | |
| 2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.444 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.444 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.444 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.444 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.444 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 3t9i | 3T9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 3vey | 0H5 | Glucokinase | 2.7.1.2 | 0.444 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.444 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.444 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.444 | |
| 4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.444 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.444 | |
| 5a3b | APR | SIR2 family protein | / | 0.444 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.443 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.443 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 1v59 | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.443 | |
| 1zq9 | SAM | Probable dimethyladenosine transferase | / | 0.443 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.443 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.443 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2ci0 | 1CM | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.443 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.443 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.443 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.443 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.443 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.443 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.443 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.443 | |
| 4dij | BLF | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.443 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.443 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.443 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.443 | |
| 4j55 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.443 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4umx | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.443 | |
| 4zca | ADP | Kinesin-like protein KIF11 | / | 0.443 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 5cdg | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1kvt | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1nxk | STU | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.442 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.442 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 2i4u | DJR | Protease | / | 0.442 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2y4g | TIR | TamL | / | 0.442 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.442 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.442 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3vfa | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 3wec | AUI | Cytochrome P450 | / | 0.442 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.442 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.442 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4iae | 1DX | Alr2278 protein | / | 0.442 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.442 | |
| 4k81 | GTP | GTPase HRas | / | 0.442 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.442 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.442 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.441 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.441 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.441 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.441 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.441 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.441 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.441 | |
| 2np9 | YE1 | (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase | / | 0.441 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3b9l | AZZ | Serum albumin | / | 0.441 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.441 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.441 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.441 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.441 | |
| 3u9e | COA | Lmo1369 protein | / | 0.441 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.441 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.441 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.441 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1gjr | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.440 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.440 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 2fxe | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.440 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.440 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.440 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.440 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.440 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.440 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.440 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.440 |