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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4kd11QKCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4kd11QKCyclin-dependent kinase 22.7.11.221.000
3r83Z14Cyclin-dependent kinase 22.7.11.220.539
3r71X86Cyclin-dependent kinase 22.7.11.220.529
3r8pZ46Cyclin-dependent kinase 22.7.11.220.521
3iggEFQCyclin-dependent kinase 22.7.11.220.518
3r7yZ04Cyclin-dependent kinase 22.7.11.220.515
2r3q5SCCyclin-dependent kinase 22.7.11.220.499
2exmZIPCyclin-dependent kinase 22.7.11.220.484
3r8vZ62Cyclin-dependent kinase 22.7.11.220.482
2c69CT8Cyclin-dependent kinase 22.7.11.220.475
4fklCK2Cyclin-dependent kinase 22.7.11.220.467
1oitHDTCyclin-dependent kinase 22.7.11.220.464
3rahO1ZCyclin-dependent kinase 22.7.11.220.463
3qzgX67Cyclin-dependent kinase 22.7.11.220.461
2c6o4SPCyclin-dependent kinase 22.7.11.220.460
3qwjX6ACyclin-dependent kinase 22.7.11.220.460
3rpo24ZCyclin-dependent kinase 22.7.11.220.456
1w8cN69Cyclin-dependent kinase 22.7.11.220.453
3r8lZ30Cyclin-dependent kinase 22.7.11.220.451
1ke5LS1Cyclin-dependent kinase 22.7.11.220.450
3qqlX03Cyclin-dependent kinase 22.7.11.220.447
4fki09KCyclin-dependent kinase 22.7.11.220.442
3r1yX76Cyclin-dependent kinase 22.7.11.220.441