sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 1.000 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.609 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.502 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.499 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.494 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.486 | |
| 1osv | CHC | Bile acid receptor | / | 0.484 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.482 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.482 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.481 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.480 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.476 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.476 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.475 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.474 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.470 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.470 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.469 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.468 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.468 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.467 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.467 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.467 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 4c2x | NHW | Glycylpeptide N-tetradecanoyltransferase 2 | / | 0.466 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.465 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.465 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.464 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.464 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.464 | |
| 2acw | UPG | Glycosyltransferase | / | 0.463 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.463 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.463 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.463 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.463 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.462 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.461 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.460 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.459 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.459 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.459 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.458 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.458 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.457 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1zdw | FLV | Prenyltransferase | / | 0.457 | |
| 3cx5 | SMA | Cytochrome b | / | 0.457 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.456 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.456 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.456 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.455 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.455 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.455 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.455 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1uio | HPR | Adenosine deaminase | 3.5.4.4 | 0.454 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.454 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.454 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4yp7 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.454 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.453 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.453 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.453 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.453 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.452 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.452 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.452 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.452 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.452 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.451 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.451 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.451 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.450 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.450 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.450 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.450 | |
| 3b2e | ADP | ATPase GET3 | / | 0.450 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.450 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.450 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.450 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.449 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.449 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.449 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.449 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.449 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.449 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.449 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.449 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.448 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.448 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2xvv | 9DN | Serum albumin | / | 0.448 | |
| 3zcw | 4A2 | Kinesin-like protein KIF11 | / | 0.448 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.448 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.448 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.448 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.448 | |
| 5a27 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.448 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.447 | |
| 1err | RAL | Estrogen receptor | / | 0.447 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.447 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.447 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.447 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.447 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.447 | |
| 3cwk | REA | Cellular retinoic acid-binding protein 2 | / | 0.447 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.447 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.447 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4b10 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4iah | 1DX | Alr2278 protein | / | 0.447 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.447 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.447 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.447 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.447 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.446 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.446 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.446 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.446 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.446 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.446 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.446 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3up0 | D7S | aceDAF-12 | / | 0.445 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.445 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.445 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.445 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1z1f | STL | Resveratrol synthase | / | 0.444 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.444 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.444 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.444 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.444 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 3sw8 | 5LI | Peptide deformylase | / | 0.444 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.444 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.443 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.443 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.443 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.443 | |
| 3fgo | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.443 | |
| 4mlh | VO2 | Glucokinase | 2.7.1.2 | 0.443 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.443 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1sn5 | T3 | Transthyretin | / | 0.442 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.442 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.442 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4l8u | 9AZ | Serum albumin | / | 0.442 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.442 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.442 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.442 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.441 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.441 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.441 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4iae | 1DX | Alr2278 protein | / | 0.441 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1ezv | SMA | Cytochrome b | / | 0.440 | |
| 1kb9 | SMA | Cytochrome b | / | 0.440 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.440 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3n6u | TSU | HTH-type transcriptional regulator TsaR | / | 0.440 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.440 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.440 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 |