sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ju1 | 1NZ | Genome polyprotein | 2.7.7.48 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ju1 | 1NZ | Genome polyprotein | 2.7.7.48 | 1.000 | |
| 4ju2 | 1O0 | Genome polyprotein | 2.7.7.48 | 0.676 | |
| 4jvq | 1ML | Genome polyprotein | 2.7.7.48 | 0.628 | |
| 4jty | 1NV | Genome polyprotein | 2.7.7.48 | 0.627 | |
| 4jtw | 1NU | Genome polyprotein | 2.7.7.48 | 0.625 | |
| 3cj3 | SX4 | Genome polyprotein | 2.7.7.48 | 0.588 | |
| 2gir | NN3 | Genome polyprotein | 2.7.7.48 | 0.558 | |
| 2o5d | VR1 | Genome polyprotein | 2.7.7.48 | 0.554 | |
| 2d3u | CCT | Polyprotein | / | 0.533 | |
| 1nhv | 154 | Genome polyprotein | 2.7.7.48 | 0.532 | |
| 1fel | FEN | Retinol-binding protein 4 | / | 0.489 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.487 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.484 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.478 | |
| 1q4g | BFL | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.474 | |
| 4pd6 | URI | Nucleoside permease | / | 0.474 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.473 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.473 | |
| 3wxy | COA | Uncharacterized protein | / | 0.473 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.472 | |
| 1sqv | UHD | Cytochrome b | / | 0.471 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1ppj | ANY | Cytochrome b | / | 0.470 | |
| 3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.469 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.468 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.468 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.467 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.467 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.465 | |
| 1eqh | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.464 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.464 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.462 | |
| 2zmd | 537 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.461 | |
| 3h1j | SMA | Cytochrome b | / | 0.461 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.461 | |
| 2ayl | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.460 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.460 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.460 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.460 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.460 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.460 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.459 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.459 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.459 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.459 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.459 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.458 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.458 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.457 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.457 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.457 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.457 | |
| 5ej8 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.457 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.456 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.456 | |
| 3n8w | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.456 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.456 | |
| 1aqb | RTL | Retinol-binding protein 4 | / | 0.455 | |
| 1kt4 | RTL | Retinol-binding protein 4 | / | 0.455 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.455 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.455 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 2oye | IM8 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.455 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 4l9q | 9TP | Serum albumin | / | 0.455 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.455 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.454 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.454 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.454 | |
| 3pcf | FHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.454 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.454 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.454 | |
| 4o4f | ATP | Kinase | / | 0.454 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.454 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.453 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.453 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.453 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.453 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.453 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.453 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.453 | |
| 3k6l | 2BB | Peptide deformylase | 3.5.1.88 | 0.453 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.453 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.453 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.452 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.452 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.452 | |
| 3eks | CY9 | Actin-5C | / | 0.452 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.452 | |
| 3llk | FAD | Sulfhydryl oxidase 1 | 1.8.3.2 | 0.452 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.452 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.452 | |
| 5ej7 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.452 | |
| 1aj8 | COA | Citrate synthase | / | 0.451 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1tys | DHF | Thymidylate synthase | / | 0.451 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.451 | |
| 2xir | 00J | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.451 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 3e8x | NAP | BH1520 protein | / | 0.451 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.451 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.451 | |
| 3wy0 | COA | Uncharacterized protein | / | 0.451 | |
| 4dpm | COA | Malonyl-CoA reductase | 1.2.1.75 | 0.451 | |
| 4l9z | COA | L-malyl-CoA/beta-methylmalyl-CoA lyase | 4.1.3.24 | 0.451 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.451 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1fbm | RTL | Cartilage oligomeric matrix protein | / | 0.450 | |
| 1ht8 | 34C | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.450 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.450 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.450 | |
| 1wc6 | TAT | Adenylate cyclase | / | 0.450 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 2a1u | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.450 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.450 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.450 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.450 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.450 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.450 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.449 | |
| 1osv | CHC | Bile acid receptor | / | 0.449 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 2imk | GTX | AGAP009194-PA | / | 0.449 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.449 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3nfa | CBJ | Gag-Pol polyprotein | / | 0.449 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.449 | |
| 4c4g | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.449 | |
| 4eo8 | 0S3 | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.449 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.449 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.449 | |
| 1d7a | AIR | N5-carboxyaminoimidazole ribonucleotide mutase | / | 0.448 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.448 | |
| 1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.448 | |
| 2cci | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.448 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.448 | |
| 3g0e | B49 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.448 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.448 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.448 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1err | RAL | Estrogen receptor | / | 0.447 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.447 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.447 | |
| 3i1f | GCP | Translation initiation factor 2 subunit gamma | / | 0.447 | |
| 3mec | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.447 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4b1v | ATP | Actin, alpha skeletal muscle | / | 0.447 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.447 | |
| 5ej6 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.447 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.446 | |
| 1pmv | 537 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.446 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.446 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.446 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.446 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.446 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.446 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.446 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2r04 | W71 | Genome polyprotein | / | 0.445 | |
| 3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.445 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.445 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.445 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.445 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.445 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1eio | GCH | Gastrotropin | / | 0.444 | |
| 1hrv | SDZ | Genome polyprotein | / | 0.444 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.444 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.444 | |
| 3ldf | SAH | Uncharacterized protein | / | 0.444 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.444 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.444 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.444 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 4ph9 | IBP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.444 | |
| 5a3b | APR | SIR2 family protein | / | 0.444 | |
| 5doz | NDP | JamJ | / | 0.444 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.443 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.443 | |
| 2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.443 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.443 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.443 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.443 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 4f1y | CNI | Glutamate receptor 3 | / | 0.443 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.443 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.443 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.443 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.442 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.442 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.442 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.442 | |
| 2gd2 | CAA | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.442 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.442 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.442 | |
| 2yiu | SMA | Cytochrome b | / | 0.442 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.442 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.442 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3vnt | 0JA | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.442 | |
| 3wd7 | COA | Acridone synthase | / | 0.442 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 5a3c | NAD | SIR2 family protein | / | 0.442 | |
| 5bsr | COA | 4-coumarate--CoA ligase 2 | 6.2.1.12 | 0.442 | |
| 5ikr | ID8 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.442 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.442 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.441 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.441 | |
| 1eqg | IBP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.441 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.441 | |
| 1u0h | ONM | Adenylate cyclase type 2 | / | 0.441 | |
| 1u0h | ONM | Adenylate cyclase type 5 | / | 0.441 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.441 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.441 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.441 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.441 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.441 | |
| 3vhk | BPK | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.441 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.441 | |
| 4j36 | 1HR | Kynurenine 3-monooxygenase | / | 0.441 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.441 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.441 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.441 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.441 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.441 | |
| 5byl | GCP | Bifunctional AAC/APH | 2.3.1 | 0.441 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.441 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.440 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.440 | |
| 1rbq | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.440 | |
| 1v8k | ANP | Kinesin-like protein KIF2C | / | 0.440 | |
| 1ybg | TAV | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 2c47 | 5ID | Casein kinase I isoform gamma-2 | / | 0.440 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.440 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.440 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 3v04 | V04 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 3zos | 0LI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.440 | |
| 4eqc | XR1 | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.440 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.440 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.440 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.440 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.440 | |
| 5kcz | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 5l7d | CLR | Smoothened homolog | / | 0.440 |