sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ja8 | 1K9 | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ja8 | 1K9 | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 1.000 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.507 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.484 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.483 | |
| 2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.480 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.478 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.477 | |
| 4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.477 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.476 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.476 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.476 | |
| 4fkg | 4CK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.474 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.474 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.474 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 1uom | PTI | Estrogen receptor | / | 0.470 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 4gub | 0Y4 | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 3a6r | FMN | FMN-binding protein | / | 0.468 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.468 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.468 | |
| 1nde | MON | Estrogen receptor beta | / | 0.467 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 3a6q | FMN | FMN-binding protein | / | 0.467 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.467 | |
| 3umw | 596 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.467 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 3anx | MTA | Polyamine aminopropyltransferase | / | 0.466 | |
| 4akn | S5B | Bromodomain-containing protein 2 | / | 0.466 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 1fvt | 106 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.465 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.465 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.465 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.464 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.464 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 4okt | 198 | Androgen receptor | / | 0.464 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.463 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.462 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.462 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.462 | |
| 4lb2 | DM5 | Serum albumin | / | 0.462 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 2o2y | TCL | Enoyl-ACP reductase | / | 0.461 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.461 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3bpt | QUE | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | 3.1.2.4 | 0.459 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.459 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.458 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2izt | 23D | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.458 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.458 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.457 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.457 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.456 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.456 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.456 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.456 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.455 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.455 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.454 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.454 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.454 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.454 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.454 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.453 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.453 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.453 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3r9o | Z71 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1y56 | FMN | Uncharacterized protein | / | 0.452 | |
| 1y56 | FMN | 382aa long hypothetical sarcosine oxidase | / | 0.452 | |
| 2gdo | 12C | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3vy5 | FMN | FMN-binding protein | / | 0.452 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.451 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.451 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.451 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.451 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.451 | |
| 3pxy | JWS | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.451 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.451 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.451 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.450 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.450 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.450 | |
| 2xnb | Y8L | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3nxe | 2NC | Protease | / | 0.450 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.450 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4hgt | 15G | Casein kinase I isoform delta | 2.7.11.1 | 0.450 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 2r3t | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.449 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.449 | |
| 3el9 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.449 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.449 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.449 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.449 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.449 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.448 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.448 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.448 | |
| 3r7i | X9I | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.448 | |
| 4bjx | 73B | Bromodomain-containing protein 4 | / | 0.448 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.448 | |
| 4ple | CPS | Nuclear receptor subfamily 5 group A member 2 | / | 0.448 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.448 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.447 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.447 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 5es7 | FON | Linear gramicidin synthase subunit A | / | 0.447 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.446 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.446 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2zoq | 5ID | Mitogen-activated protein kinase 3 | 2.7.11.24 | 0.446 | |
| 3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.446 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.446 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.446 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.446 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.445 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.445 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.445 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.445 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.445 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2o2s | TCL | Enoyl-acyl carrier reductase | / | 0.444 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3cyx | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3r3c | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.444 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.444 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4apu | A2K | Progesterone receptor | / | 0.444 | |
| 4c2u | ANP | DNA helicase | / | 0.444 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.444 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.444 | |
| 4g1w | G1W | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.444 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.444 | |
| 4j5j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.444 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.444 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.444 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.443 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.443 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.443 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.443 | |
| 1rbq | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.443 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.443 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.443 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2fxd | DR7 | Pol polyprotein | / | 0.443 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.443 | |
| 2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3kdu | NKS | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.443 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.443 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.443 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.443 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.443 | |
| 5dt4 | ATP | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.442 | |
| 2pog | WST | Estrogen receptor | / | 0.442 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.442 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.442 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.442 | |
| 3oq6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.442 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.442 | |
| 3zls | 92P | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.442 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.442 | |
| 4iu7 | 1GM | Estrogen receptor | / | 0.442 | |
| 4j0r | 1H2 | Bromodomain-containing protein 4 | / | 0.442 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.442 | |
| 1b38 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.441 | |
| 2p3a | 3TL | Pol protein | / | 0.441 | |
| 2r5q | 1UN | Gag-Pol polyprotein | / | 0.441 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.441 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.441 | |
| 3kfs | 3TL | Gag-Pol polyprotein | / | 0.441 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.441 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.441 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.441 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 4fkt | 48K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.441 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.441 | |
| 1w1r | ZEA | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.440 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 2ibz | SMA | Cytochrome b | / | 0.440 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.440 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2pnu | ENM | Androgen receptor | / | 0.440 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.440 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3cgd | NAD | Coenzyme A disulfide reductase | / | 0.440 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.440 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.440 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4nvk | 2NY | Peroxidase | / | 0.440 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.440 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.440 |