Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4j7xSASSepiapterin reductase1.1.1.153

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4j7xSASSepiapterin reductase1.1.1.1531.000
4j7uYTZSepiapterin reductase1.1.1.1530.644
4hwkSFYSepiapterin reductase1.1.1.1530.540
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.513
3g8eIS1Nicotinamide phosphoribosyltransferase2.4.2.120.511
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.501
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.501
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.498
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.497
2ociTYCValacyclovir hydrolase3.10.496
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.496
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.494
1x8lOXRRetinol dehydratase/0.492
3koo24DBifunctional epoxide hydrolase 23.3.2.100.492
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.492
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.491
2hl0A3SThreonine--tRNA ligase6.1.1.30.491
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.491
2ovmAS0Progesterone receptor/0.490
1fmjRTLRetinol dehydratase/0.489
1vj3TABDihydrofolate reductase1.5.1.30.488
2gpuOHTEstrogen-related receptor gamma/0.487
4ia1BIVVitamin D3 receptor A/0.487
4ia7BIVVitamin D3 receptor A/0.487
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.486
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.485
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.485
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.485
3bejMUFBile acid receptor/0.484
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.484
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.484
1klkPMDDihydrofolate reductase1.5.1.30.483
3cseN22Uncharacterized protein/0.483
3jwm5WBDihydrofolate reductase/0.483
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.483
2fzhDH1Dihydrofolate reductase1.5.1.30.482
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.482
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.482
4ia3BIVVitamin D3 receptor A/0.482
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.481
1nhz486Glucocorticoid receptor/0.481
2fziDH3Dihydrofolate reductase1.5.1.30.481
2ovhAS0Progesterone receptor/0.481
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.481
1qknRALEstrogen receptor beta/0.480
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.480
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.480
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.479
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.479
3vt7VDXVitamin D3 receptor/0.479
3vtcTK3Vitamin D3 receptor/0.479
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.479
1dajMOTDihydrofolate reductase1.5.1.30.478
1ppjANYCytochrome b/0.478
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.476
2po7CHDFerrochelatase, mitochondrial4.99.1.10.476
1errRALEstrogen receptor/0.475
2fszOHTEstrogen receptor beta/0.475
3ipq965Oxysterols receptor LXR-alpha/0.475
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.475
2fpcSCGStrictosidine synthase4.3.3.20.474
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.474
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
5hs1VORLanosterol 14-alpha demethylase/0.474
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
3s79ASDAromatase1.14.14.140.473
1hfqMOTDihydrofolate reductase1.5.1.30.472
2bj4OHTEstrogen receptor/0.472
3qlxQLRUncharacterized protein/0.472
3h3r14HCollagen type IV alpha-3-binding protein/0.471
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.1460.471
1o5rFR9Adenosine deaminase3.5.4.40.470
2qblCAMCamphor 5-monooxygenase1.14.15.10.470
3fwjCAMCamphor 5-monooxygenase1.14.15.10.470
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.470
3qly55VUncharacterized protein/0.470
4iaq2GM5-hydroxytryptamine receptor 1B/0.470
4ixgIXGDihydrofolate reductase1.5.1.30.470
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
2zb45OPProstaglandin reductase 21.3.1.480.469
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.469
3jwcEKBDihydrofolate reductase/0.469
4qofFMNRibosyldihydronicotinamide dehydrogenase [quinone]/0.469
1wsvTHHAminomethyltransferase, mitochondrial/0.468
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.468
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.467
2rhrEMOPutative ketoacyl reductase1.3.10.467
2z97CAMCamphor 5-monooxygenase1.14.15.10.467
4apuA2KProgesterone receptor/0.467
4kfp1R7Nicotinamide phosphoribosyltransferase2.4.2.120.467
4olfHFGProline--tRNA ligase6.1.1.150.467
1iwiCAMCamphor 5-monooxygenase1.14.15.10.466
1r2jFADFkbI/0.466
1uyePU9Heat shock protein HSP 90-alpha/0.466
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.466
3kpzZNEVitamin D3 receptor/0.466
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.466
4h9506UDihydrofolate reductase1.5.1.30.466
4o281QSNicotinamide phosphoribosyltransferase2.4.2.120.466
6cp4CAMCamphor 5-monooxygenase1.14.15.10.466
1cd2FOLDihydrofolate reductase1.5.1.30.465
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
3vrwYS5Vitamin D3 receptor/0.465
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
2bxqIMNSerum albumin/0.464
2feuCAMCamphor 5-monooxygenase1.14.15.10.464
2g97DGBNicotinamide phosphoribosyltransferase2.4.2.120.464
2m56CAMCamphor 5-monooxygenase1.14.15.10.464
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
2qbnCAMCamphor 5-monooxygenase1.14.15.10.464
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.464
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.464
4nx6FOLDihydrofolate reductase1.5.1.30.464
1dz6CAMCamphor 5-monooxygenase1.14.15.10.463
1uy8PU5Heat shock protein HSP 90-alpha/0.463
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
3jpuTY4Transcriptional activator protein LasR/0.463
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
4fki09KCyclin-dependent kinase 22.7.11.220.463
4gk2L66Ephrin type-A receptor 32.7.10.10.463
4ktkKTKCytochrome P450/0.463
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
2a1nCAMCamphor 5-monooxygenase1.14.15.10.462
3eek53SUncharacterized protein/0.462
3v1s0LHStrictosidine synthase4.3.3.20.462
4a83DXCMajor pollen allergen Bet v 1-A/0.462
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.462
1f28UMPThymidylate synthase2.1.1.450.461
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
4enhFVXCholesterol 24-hydroxylase/0.461
4fj0HHF17beta-hydroxysteroid dehydrogenase/0.461
4g1d0VKVitamin D3 receptor A/0.461
4m6p20RNicotinamide phosphoribosyltransferase2.4.2.120.461
4ruoBIVVitamin D3 receptor A/0.461
1dtpAPUDiphtheria toxin/0.460
2fwyH64Heat shock protein HSP 90-alpha/0.460
2p7zOHTEstrogen-related receptor gamma/0.460
3csdEMOPutative ketoacyl reductase1.3.10.460
3inwJZBHeat shock protein HSP 90-alpha/0.460
3oom507Activin receptor type-12.7.11.300.460
3w78CBDFMN-dependent NADH-azoreductase/0.460
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.460
4ktf1TMCytochrome P450/0.460
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.459
2uxhQUEHTH-type transcriptional regulator TtgR/0.459
3ixp834Ecdysone receptor/0.459
3jw5TOPDihydrofolate reductase/0.459
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.459
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4l4aCAMCamphor 5-monooxygenase1.14.15.10.459
3emlZMAAdenosine receptor A2a/0.459
1cjkFOKAdenylate cyclase type 2/0.458
1cjkFOKAdenylate cyclase type 5/0.458
1t85CAMCamphor 5-monooxygenase1.14.15.10.458
2hasC3OVitamin D3 receptor/0.458
3a1l2CCCytochrome P450/0.458
3fwfCAMCamphor 5-monooxygenase1.14.15.10.458
3glmCOOGlutaconyl-CoA decarboxylase alpha subunit/0.458
3pqbVGPPutative oxidoreductase/0.458
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.458
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.458
4i8vBHFCytochrome P450 1A11.14.14.10.458
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.458
1nasASESepiapterin reductase1.1.1.1530.457
1t88CAMCamphor 5-monooxygenase1.14.15.10.457
1x2hLPALipoate-protein ligase A6.3.1.200.457
2w8y486Progesterone receptor/0.457
2z3uCRRCytochrome P450/0.457
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.457
4cdmFO1Deoxyribodipyrimidine photolyase/0.457
4ia2BIVVitamin D3 receptor A/0.457
4j6dTESCytochrome P450 monooxygenase/0.457
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.457
1fmlRTLRetinol dehydratase/0.456
1uy9PU6Heat shock protein HSP 90-alpha/0.456
1uydPU8Heat shock protein HSP 90-alpha/0.456
2x7hPFNProstaglandin reductase 310.456
2xvw9NRSerum albumin/0.456
2yatEEUEstrogen receptor/0.456
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3h18PMSEsterase/lipase/0.456
3q9bB3NAcetylpolyamine amidohydrolase/0.456
3sa27DRDihydrofolate reductase/0.456
4iteTEYVitamin D3 receptor/0.456
4l4bCAMCamphor 5-monooxygenase1.14.15.10.456
1dkfBMSRetinoic acid receptor alpha/0.455
1eioGCHGastrotropin/0.455
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1rx1NAPDihydrofolate reductase1.5.1.30.455
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.455
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.455
3eem53VUncharacterized protein/0.455
3hz5Z64Heat shock protein HSP 90-alpha/0.455
3kjm245Cytokinin dehydrogenase 11.5.99.120.455
3lakKR1Gag-Pol polyprotein2.7.7.490.455
3qlzQLZUncharacterized protein/0.455
4ele31IDihydrofolate reductase/0.455
4h4m494Gag-Pol polyprotein2.7.7.490.455
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.455
4jlj1NMDeoxycytidine kinase2.7.1.740.455
4o701QKBromodomain-containing protein 4/0.455
4rujVDXVitamin D3 receptor A/0.455
4uyg73BBromodomain-containing protein 2/0.455
4x5iFOLDihydrofolate reductase1.5.1.30.455
1k749CRRetinoic acid receptor RXR-alpha/0.454
1m7aMQUDihydrofolate reductase1.5.1.30.454
1uy7PU4Heat shock protein HSP 90-alpha/0.454
3gfbNADL-threonine 3-dehydrogenase/0.454
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
3l63CAMCamphor 5-monooxygenase1.14.15.10.454
3wrlCAMCamphor 5-monooxygenase1.14.15.10.454
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4b2wBZ0Glucose-1-phosphate thymidylyltransferase/0.454
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.454
5cvhADPCasein kinase II subunit alpha2.7.11.10.454
1axwMTXThymidylate synthase/0.453
1diuBDMDihydrofolate reductase1.5.1.30.453
1dz8CAMCamphor 5-monooxygenase1.14.15.10.453
1gebCAMCamphor 5-monooxygenase1.14.15.10.453
1l2jETCEstrogen receptor beta/0.453
1m13HYFNuclear receptor subfamily 1 group I member 2/0.453
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.453
1uomPTIEstrogen receptor/0.453
2zlaVDBVitamin D3 receptor/0.453
3h3t16HCollagen type IV alpha-3-binding protein/0.453
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.453
3vt65YIVitamin D3 receptor/0.453
3vtbTKAVitamin D3 receptor/0.453
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.453
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
4nc3ERM5-hydroxytryptamine receptor 2B/0.453
4ug91EWNitric oxide synthase oxygenase1.14.13.1650.453
4uugPXGBranched-chain amino acid aminotransferase, putative/0.453
1m78CLZDihydrofolate reductase1.5.1.30.452
1og5SWFCytochrome P450 2C9/0.452
1uymPU3Heat shock protein HSP 90-beta/0.452
1wxyFRKAdenosine deaminase3.5.4.40.452
1xxjUNCUricase1.7.3.30.452
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.452
2acwUPGGlycosyltransferase/0.452
2f8pCEIObelin/0.452
2gvjDGBNicotinamide phosphoribosyltransferase2.4.2.120.452
2ij7TPFMycocyclosin synthase1.14.21.90.452
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.452
2pnuENMAndrogen receptor/0.452
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.452
3elm24FCollagenase 33.4.240.452
3fwiCAMCamphor 5-monooxygenase1.14.15.10.452
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
3gwfFADCyclohexanone monooxygenase/0.452
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4ckcSAHmRNA-capping enzyme catalytic subunit2.1.1.560.452
4efuEFUHeat shock protein HSP 90-alpha/0.452
4fhi0S4Vitamin D3 receptor A/0.452
4g3rCAMCamphor 5-monooxygenase1.14.15.10.452
4oxiGAPEnterobactin synthetase component F-related protein/0.452
4rupH97Vitamin D3 receptor A/0.452
1ie9VDXVitamin D3 receptor/0.451
1iwjCAMCamphor 5-monooxygenase1.14.15.10.451
2g1n1IGRenin3.4.23.150.451
2qjySMACytochrome b/0.451
2uxuNARHTH-type transcriptional regulator TtgR/0.451
3c3eGDP2-phospho-L-lactate transferase/0.451
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.451
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.451
3v49PK0Androgen receptor/0.451
3vt9YI4Vitamin D3 receptor/0.451
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.451
4h9753SDihydrofolate reductase1.5.1.30.451
4l0qNADAlcohol dehydrogenase class-3/0.451
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.451
1cjcFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.450
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
1uyuCAMCamphor 5-monooxygenase1.14.15.10.450
1yrdCAMCamphor 5-monooxygenase1.14.15.10.450
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
3h3qH13Collagen type IV alpha-3-binding protein/0.450
3mdmFJZCholesterol 24-hydroxylase/0.450
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.450
4b1rITCTetracycline repressor protein class D/0.450
4ek1CAMCamphor 5-monooxygenase1.14.15.10.450
4kkyCAMCamphor 5-monooxygenase1.14.15.10.450
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4o71CPBBromodomain-containing protein 4/0.450
4q0a4OAVitamin D3 receptor A/0.450
1tl7FOKAdenylate cyclase type 2/0.449
1tl7FOKAdenylate cyclase type 5/0.449
1uyfPU1Heat shock protein HSP 90-alpha/0.449
2aclREARetinoic acid receptor RXR-alpha/0.449
2q9fC3SCholesterol 24-hydroxylase/0.449
2ykjYKJHeat shock protein HSP 90-alpha/0.449
2zbaZBATrichothecene 3-O-acetyltransferase/0.449
2zzaFOLDihydrofolate reductase/0.449
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
3och2MXDihydrofolate reductase1.5.1.30.449
3w0c6DSVitamin D3 receptor/0.449
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.449
4hy6FJ1Heat shock protein HSP 90-alpha/0.449
4l4dCAMCamphor 5-monooxygenase1.14.15.10.449
4nb6444Nuclear receptor ROR-gamma/0.449
4wa9AXITyrosine-protein kinase ABL12.7.10.20.449
5ab7MLCNonspecific lipid-transfer protein, putative/0.449
5k2aZMAAdenosine receptor A2a/0.449
3pwhZMAAdenosine receptor A2a/0.449
1blzACVIsopenicillin N synthase1.21.3.10.448
1bwlFMNNADPH dehydrogenase 11.6.99.10.448
1f4gTP4Thymidylate synthase/0.448
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.448
1o6qR17Squalene--hopene cyclase4.2.1.1290.448
1o76CAMCamphor 5-monooxygenase1.14.15.10.448
1s3yTQTDihydrofolate reductase1.5.1.30.448
1t87CAMCamphor 5-monooxygenase1.14.15.10.448
2hcdBIVVitamin D3 receptor A/0.448
2jf9OHTEstrogen receptor/0.448
2o4rVD5Vitamin D3 receptor/0.448
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.448
2yee2ECHeat shock protein HSP 90-alpha/0.448
3bfa9ODOdorant binding protein ASP1/0.448
3elySAHMethyltransferase/0.448
3nr4PYVAbscisic acid receptor PYL2/0.448
3td8D2RDihydrofolate reductase1.5.1.30.448
3uvvREARetinoic acid receptor RXR-alpha/0.448
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
1nooCAHCamphor 5-monooxygenase1.14.15.10.447
1pq6965Oxysterols receptor LXR-beta/0.447
1s3vTQDDihydrofolate reductase1.5.1.30.447
1uhlMEIRetinoic acid receptor RXR-beta/0.447
1xddAAYIntegrin alpha-L/0.447
2bxmIMNSerum albumin/0.447
2g0gSP0Peroxisome proliferator-activated receptor gamma/0.447
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
2wo7ASVIsopenicillin N synthase1.21.3.10.447
3bfb9ODPheromone-binding protein ASP1/0.447
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3dauMTXDihydrofolate reductase1.5.1.30.447
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3ictADPCoenzyme A disulfide reductase/0.447
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.447
3qiyQI1Botulinum neurotoxin type A3.4.24.690.447
3srqQ19Dihydrofolate reductase1.5.1.30.447
3wiyLC6Induced myeloid leukemia cell differentiation protein Mcl-1/0.447
4a6rTA8Probable aminotransferase/0.447
1ezfIN0Squalene synthase2.5.1.210.446
1iyzNDPProbable quinone oxidoreductase/0.446
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.446
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1m79MQ1Dihydrofolate reductase1.5.1.30.446
1t86CAMCamphor 5-monooxygenase1.14.15.10.446
1zgaHMKIsoflavone 4'-O-methyltransferase/0.446
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2harOCCVitamin D3 receptor/0.446
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.446
2qboCAMCamphor 5-monooxygenase1.14.15.10.446
2zevB71Geranylgeranyl pyrophosphate synthase/0.446
2zjwREFCasein kinase II subunit alpha2.7.11.10.446
3aqaBYHBromodomain-containing protein 2/0.446
3ddw055Glycogen phosphorylase, liver form2.4.1.10.446
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.446
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.446
3fwgCAMCamphor 5-monooxygenase1.14.15.10.446
3gwfNAPCyclohexanone monooxygenase/0.446
3p3zP3ZPutative cytochrome P450/0.446
3roy22ZCyclin-dependent kinase 22.7.11.220.446
3vrvYSDVitamin D3 receptor/0.446
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4gevCB3Thymidylate synthase/0.446
1aoeGW3Dihydrofolate reductase1.5.1.30.445
1kkq471Peroxisome proliferator-activated receptor alpha/0.445
1uofPNNDeacetoxycephalosporin C synthase1.14.20.10.445
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
2cd2FOLDihydrofolate reductase1.5.1.30.445
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2rqfJH3Hemolymph juvenile hormone binding protein/0.445
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.445
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3l0lHC3Nuclear receptor ROR-gamma/0.445
3mdvCL6Cholesterol 24-hydroxylase/0.445
3p99LNPLanosterol 14-alpha-demethylase/0.445
3u8hBHPPhospholipase A2, membrane associated/0.445
3wrhCAMCamphor 5-monooxygenase1.14.15.10.445
4egnTWOCytochrome P450/0.445
4klrCHDFerrochelatase, mitochondrial4.99.1.10.445
4nh82LCHeat shock protein HSP 90-alpha/0.445
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.445
4ug71EVNitric oxide synthase oxygenase1.14.13.1650.445
4xe606UDihydrofolate reductase1.5.1.30.445
4zm6ACON-acetyl-beta-D glucosaminidase/0.445
1gwqZTWEstrogen receptor/0.444
1r35I58Nitric oxide synthase, inducible1.14.13.390.444
1uyhPU0Heat shock protein HSP 90-alpha/0.444
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2jfaRALEstrogen receptor/0.444
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.444
3c1oNAPEugenol synthase/0.444
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3m7rVDXVitamin D3 receptor/0.444
3vt8YI3Vitamin D3 receptor/0.444
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4cd2FOLDihydrofolate reductase1.5.1.30.444
4eh4IRGMitogen-activated protein kinase 14/0.444
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
4j6cSTRCytochrome P450 monooxygenase/0.444
4kjjFOLDihydrofolate reductase1.5.1.30.444
4l4fCAMCamphor 5-monooxygenase1.14.15.10.444
4lsjLSJGlucocorticoid receptor/0.444
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.444
5cp4CAMCamphor 5-monooxygenase1.14.15.10.444
5k2cZMAAdenosine receptor A2a/0.444
1dyrTOPDihydrofolate reductase1.5.1.30.443
1e26GPBDihydrofolate reductase1.5.1.30.443
1ia2TQ4Dihydrofolate reductase1.5.1.30.443
1rx6DDFDihydrofolate reductase1.5.1.30.443
1thnADPAnti-sigma F factor/0.443
2iyaZIOOleandomycin glycosyltransferase/0.443
2qbmCAMCamphor 5-monooxygenase1.14.15.10.443
2uxiG50HTH-type transcriptional regulator TtgR/0.443
2vbpVB1Isopenicillin N synthase1.21.3.10.443
2wi4ZZ4Heat shock protein HSP 90-alpha/0.443
2xvv9DNSerum albumin/0.443
3cd2MTXDihydrofolate reductase1.5.1.30.443
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.443
3d0bSNXHeat shock protein HSP 90-alpha/0.443
3datMTXDihydrofolate reductase/0.443
3dg8NDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3eej53RUncharacterized protein/0.443
3ix4TX1Transcriptional activator protein LasR/0.443
3o0iP54Heat shock protein HSP 90-alpha/0.443
3stv3HOMethylketone synthase I/0.443
3vqvANPPyrrolysine--tRNA ligase/0.443
3vtdTKDVitamin D3 receptor/0.443
3w0aDS5Vitamin D3 receptor/0.443
3w5tLHPVitamin D3 receptor/0.443
4aoxFADSteroid monooxygenase/0.443
4g2gTDHMycocyclosin synthase1.14.21.90.443
4g47TZFMycocyclosin synthase1.14.21.90.443
4iq71G9Mycocyclosin synthase1.14.21.90.443
4itfTFYVitamin D3 receptor/0.443
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.443
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4psbGA3Cytokinin-specific binding protein/0.443
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.443
5prcATZReaction center protein L chain/0.443
1a72PADAlcohol dehydrogenase E chain1.1.1.10.442
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1db1VDXVitamin D3 receptor/0.442
1kzjCB3Thymidylate synthase/0.442
1s0zEB1Vitamin D3 receptor/0.442
1umlFR4Adenosine deaminase3.5.4.40.442
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.442
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
2npxNADNADH peroxidase1.11.1.10.442
2wi72KLHeat shock protein HSP 90-alpha/0.442
3cppCAMCamphor 5-monooxygenase1.14.15.10.442
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
3d75NBBPheromone-binding protein ASP1/0.442
3fzwEQUSteroid Delta-isomerase5.3.3.10.442
3jzfJZKBiotin carboxylase6.3.4.140.442
3mg3ECHOrange carotenoid-binding protein/0.442
3nmpPYVAbscisic acid receptor PYL2/0.442
3u8dU8DPhospholipase A2, membrane associated/0.442
3v94WYQPhosphodiesterase/0.442
3vrtYS2Vitamin D3 receptor/0.442
4fj2QSO17beta-hydroxysteroid dehydrogenase/0.442
4g210VPVitamin D3 receptor A/0.442
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.442
4k9oTPPBenzoylformate decarboxylase4.1.1.70.442
4kfj1R0Dihydrofolate reductase1.5.1.30.442
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
4ktl1CQCytochrome P450/0.442
4yekTHMThymidine phosphorylase/0.442
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1phgMYTCamphor 5-monooxygenase1.14.15.10.441
1rdtL79Retinoic acid receptor RXR-alpha/0.441
1rkhVD2Vitamin D3 receptor/0.441
1sepBIOSepiapterin reductase1.1.1.1530.441
1upw444Oxysterols receptor LXR-beta/0.441
1x1aSAMC-20 methyltransferase/0.441
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2h55DZ8Heat shock protein HSP 90-alpha/0.441
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.441
2iw5FADLysine-specific histone demethylase 1A10.441
2zl9VDAVitamin D3 receptor/0.441
3fc6REARetinoic acid receptor RXR-alpha/0.441
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.441
3tm5SFGUncharacterized protein/0.441
3vruYS3Vitamin D3 receptor/0.441
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.441
3w5rLOAVitamin D3 receptor/0.441
4a81DXCMajor pollen allergen Bet v 1-A/0.441
4bfpSWYTankyrase-22.4.2.300.441
4boeCLRJapanin/0.441
4eh9IRGMitogen-activated protein kinase 14/0.441
4fogC2FThymidylate synthase ThyA/0.441
4g2fC07Ephrin type-A receptor 32.7.10.10.441
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.441
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.441
4ib4ERM5-hydroxytryptamine receptor 2B/0.441
4jvr1MTE3 ubiquitin-protein ligase Mdm26.3.20.441
4kak06UDihydrofolate reductase1.5.1.30.441
4y8wSTRSteroid 21-hydroxylase/0.441
5k2bZMAAdenosine receptor A2a/0.441
1aiqCB3Thymidylate synthase/0.440
1dnaCB3Thymidylate synthase/0.440
1ndzFR5Adenosine deaminase3.5.4.40.440
1yinCM3Estrogen receptor/0.440
2a1oCAMCamphor 5-monooxygenase1.14.15.10.440
2c4jGSOGlutathione S-transferase Mu 22.5.1.180.440
2hb7O1CVitamin D3 receptor/0.440
2qg2A91Heat shock protein HSP 90-alpha/0.440
2y37A54Nitric oxide synthase, inducible1.14.13.390.440
2zawCAMCamphor 5-monooxygenase1.14.15.10.440
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3pgiF41Endothiapepsin3.4.23.220.440
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.440
3r6xX84Cyclin-dependent kinase 22.7.11.220.440
3w5p4OAVitamin D3 receptor/0.440
4dbw511Aldo-keto reductase family 1 member C3/0.440
4i6gFADCryptochrome-2/0.440
4jhz1KVBeta-glucuronidase3.2.1.310.440
4m4922YL-lactate dehydrogenase A chain1.1.1.270.440
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.440