sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 | 1.000 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.629 | |
| 4hwk | SFY | Sepiapterin reductase | 1.1.1.153 | 0.618 | |
| 1nas | ASE | Sepiapterin reductase | 1.1.1.153 | 0.563 | |
| 1sep | BIO | Sepiapterin reductase | 1.1.1.153 | 0.517 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.485 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.483 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.481 | |
| 4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.478 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.474 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.474 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.473 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.472 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.472 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.472 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.471 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.471 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.471 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.470 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.470 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.469 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.469 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.469 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.467 | |
| 2pnu | ENM | Androgen receptor | / | 0.467 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.467 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.466 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.466 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.465 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.465 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.464 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.464 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.462 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.462 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.461 | |
| 3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.460 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.460 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.459 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.459 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.459 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.459 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.458 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2xvv | 9DN | Serum albumin | / | 0.458 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.458 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.458 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.458 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.457 | |
| 1r2j | FAD | FkbI | / | 0.457 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.457 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3v49 | PK0 | Androgen receptor | / | 0.457 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.457 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.457 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.456 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.456 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.456 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.456 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.455 | |
| 4ha6 | PXM | Pyridoxine 4-oxidase | / | 0.455 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.454 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.454 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.454 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.454 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.453 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.453 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.453 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.453 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.453 | |
| 1fml | RTL | Retinol dehydratase | / | 0.452 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.452 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.452 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.452 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.452 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.452 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.452 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.452 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.452 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.452 | |
| 1axw | MTX | Thymidylate synthase | / | 0.451 | |
| 2acw | UPG | Glycosyltransferase | / | 0.451 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.451 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 3e01 | PZ2 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.451 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.451 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.451 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.451 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.450 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.450 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4bwa | N0B | Pyrrolysine--tRNA ligase | / | 0.450 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.450 | |
| 4iae | 1DX | Alr2278 protein | / | 0.450 | |
| 4nqm | Y1Z | Bromodomain-containing protein 4 | / | 0.450 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.450 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.450 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.449 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.449 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.449 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.449 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.448 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.448 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.448 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.448 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.448 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.448 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.448 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.448 | |
| 1eio | GCH | Gastrotropin | / | 0.447 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.447 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.447 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.447 | |
| 3dol | GWI | Pol protein | / | 0.447 | |
| 3fbs | FAD | Oxidoreductase | / | 0.447 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.447 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.447 | |
| 4lvg | 20O | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.447 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.447 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.446 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.446 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.446 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.446 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.446 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.446 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.446 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.445 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.445 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.445 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.445 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.445 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3tgy | ASC | Lactoperoxidase | 1.11.1.7 | 0.445 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.445 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.445 | |
| 4apu | A2K | Progesterone receptor | / | 0.445 | |
| 4asy | N5Y | Glucose-1-phosphate thymidylyltransferase | / | 0.445 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.445 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.445 | |
| 1fxo | TMP | Glucose-1-phosphate thymidylyltransferase | / | 0.444 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.444 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.444 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.444 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.444 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.444 | |
| 2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.444 | |
| 3dya | PZL | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.444 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.444 | |
| 4a0s | CO8 | Octenoyl-CoA reductase/carboxylase | / | 0.444 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.444 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.444 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.443 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.443 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.443 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.443 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.443 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.442 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.442 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1xxj | UNC | Uricase | 1.7.3.3 | 0.442 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.442 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.442 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2xvw | 9NR | Serum albumin | / | 0.442 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.442 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.442 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.442 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.442 | |
| 4ere | 0R2 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.442 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4odo | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.442 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.441 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.441 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.441 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.441 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.441 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1h1p | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.440 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.440 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.440 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.440 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.440 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.440 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.440 | |
| 4l8u | 9AZ | Serum albumin | / | 0.440 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.440 | |
| 4o95 | 245 | Cytokinin dehydrogenase 4 | / | 0.440 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.440 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.440 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4xwt | U5P | Ribonuclease J | / | 0.440 | |
| 5a3b | APR | SIR2 family protein | / | 0.440 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.440 |