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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4j3mAJ8Tankyrase-22.4.2.30

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4j3mAJ8Tankyrase-22.4.2.301.000
3u9y09LTankyrase-22.4.2.300.591
4tkg09LTankyrase-22.4.2.300.584
4krs1SXTankyrase-12.4.2.300.577
4pnrG18Tankyrase-22.4.2.300.569
4bj9UHBTankyrase-22.4.2.300.561
4pnmNU1Tankyrase-22.4.2.300.540
4mt92D6Tankyrase-12.4.2.300.512
4li71XPTankyrase-12.4.2.300.511
4tjy3GNTankyrase-22.4.2.300.511
4n4v2GYTankyrase-12.4.2.300.508
4k4eK4ETankyrase-12.4.2.300.507
4bjbP34Tankyrase-22.4.2.300.499
4li81XQTankyrase-12.4.2.300.499
4bjcRPBTankyrase-22.4.2.300.498
4msg2C6Tankyrase-12.4.2.300.498
4i9i1DYTankyrase-12.4.2.300.480
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.471
2zitNADExotoxin A2.4.2.360.470
4hyf1AKTankyrase-22.4.2.300.470
3b8hNADExotoxin A2.4.2.360.461
4n4t2GVTankyrase-12.4.2.300.457
4k4fK4FTankyrase-12.4.2.300.454
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.300.449
4bfpSWYTankyrase-22.4.2.300.446
1xk9P34Exotoxin A2.4.2.360.442