sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.849 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.847 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.840 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.839 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.838 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.833 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.830 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.823 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.821 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.817 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.807 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.806 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.805 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.804 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.803 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.802 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.802 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.801 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.792 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.792 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.789 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.785 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.785 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.782 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.780 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.779 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.778 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.778 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.776 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.768 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.768 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.768 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.764 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.763 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.763 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.760 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.757 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.754 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.753 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.752 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.749 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.748 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.738 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.736 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.729 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.710 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.699 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.683 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.627 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.620 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.608 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.593 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.586 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.584 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.583 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.581 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.577 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.572 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.561 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.559 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.555 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.541 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.533 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.529 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.520 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.518 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.518 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.509 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.497 | |
| 4iae | 1DX | Alr2278 protein | / | 0.490 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.480 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.475 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.473 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.472 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.472 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.471 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.469 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.469 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.469 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.469 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.468 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.468 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.467 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.466 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.465 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.465 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.462 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.462 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.461 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.460 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.460 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.460 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.458 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.458 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.457 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.457 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.457 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4jic | FMN | GTN Reductase | / | 0.457 | |
| 4js1 | CTN | Beta-galactoside alpha-2,6-sialyltransferase 1 | 2.4.99.1 | 0.457 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.455 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.455 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.455 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.454 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.454 | |
| 4y1b | NAP | AntE | / | 0.454 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.453 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.453 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.453 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.453 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.452 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.452 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.452 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.452 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.451 | |
| 1q51 | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.451 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.451 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.451 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.450 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.450 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.450 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.449 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.449 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.449 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.449 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.449 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.449 | |
| 4e2d | FMN | Dehydrogenase | / | 0.449 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.449 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.449 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.448 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.448 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 4n1g | CEI | Obelin | / | 0.448 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.448 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.447 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.447 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.447 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.447 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.447 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.447 | |
| 4iah | 1DX | Alr2278 protein | / | 0.447 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.447 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.446 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.446 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.446 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.446 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.446 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.444 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.444 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.444 | |
| 3v2u | ATP | Protein GAL3 | / | 0.444 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.444 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.443 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.443 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.442 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.442 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.442 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.442 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 1jf2 | CZH | Obelin | / | 0.441 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.441 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 1e2n | RCA | Thymidine kinase | / | 0.440 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.440 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.440 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.440 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.440 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.440 |