sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.892 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.880 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.870 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.853 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.849 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.846 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.842 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.833 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.826 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.826 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.813 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.808 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.804 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.801 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.800 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.799 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.796 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.790 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.790 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.789 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.786 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.785 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.784 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.783 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.779 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.777 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.776 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.770 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.770 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.766 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.761 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.751 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.750 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.747 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.746 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.740 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.738 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.738 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.737 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.731 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.730 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.725 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.712 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.683 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.608 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.591 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.585 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.585 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.581 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.574 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.572 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.571 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.556 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.551 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.543 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.541 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.540 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.531 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.529 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.528 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.521 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.519 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.513 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.505 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.505 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.503 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.500 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.500 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.497 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.495 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.494 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.492 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.491 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.489 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.487 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.485 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.484 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.483 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.483 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.481 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.480 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.480 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.479 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.479 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.478 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.478 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.478 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.477 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.477 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.476 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.476 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.475 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.475 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.474 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.474 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.474 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.474 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.473 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.472 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.472 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.472 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.472 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.472 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.471 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.471 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 4iae | 1DX | Alr2278 protein | / | 0.471 | |
| 4iah | 1DX | Alr2278 protein | / | 0.471 | |
| 4rel | KMP | Glycosyltransferase | / | 0.471 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.470 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.470 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.470 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.470 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.470 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.469 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.469 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.469 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.468 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.468 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.467 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.466 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.466 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.466 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.465 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.465 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.465 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.465 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.464 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.464 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.464 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.463 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.463 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.463 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.463 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.463 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.463 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.463 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.462 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.462 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.462 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.462 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.462 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.462 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.462 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.462 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.462 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.461 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.461 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.460 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.460 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.460 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.460 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.460 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.459 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3e6e | DCS | Alanine racemase | / | 0.459 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.459 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.459 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.459 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.459 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.459 | |
| 4ykl | GMP | Aprataxin-like protein | 3 | 0.459 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.459 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.458 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.458 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.458 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.458 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.458 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.458 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.457 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.457 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.457 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.457 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.457 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.457 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.457 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.457 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.457 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.457 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.457 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.457 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.456 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.456 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.456 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.455 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.455 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.455 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.455 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.455 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.455 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.455 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.454 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.454 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.454 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.454 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.454 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.454 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.454 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.454 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.453 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.453 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.453 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.453 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.453 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4jic | FMN | GTN Reductase | / | 0.453 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.453 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.453 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.452 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.452 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.452 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.452 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.452 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.452 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.452 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.451 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.451 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.451 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.451 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.451 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.451 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.451 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.451 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.451 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.451 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.451 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.451 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.451 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.451 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.451 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.451 | |
| 4e2b | FMN | Dehydrogenase | / | 0.451 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.450 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.450 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.450 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.450 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.450 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.450 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.450 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.450 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.450 | |
| 3vp6 | HLD | Glutamate decarboxylase 1 | 4.1.1.15 | 0.450 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.450 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.450 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 1bxs | NAD | Retinal dehydrogenase 1 | 1.2.1.36 | 0.449 | |
| 1bzm | MZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.449 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.449 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.449 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.449 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.449 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.449 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.449 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.449 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.449 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.449 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.449 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3eks | CY9 | Actin-5C | / | 0.449 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.449 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.449 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.449 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.449 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.449 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.449 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.449 | |
| 4e2d | FMN | Dehydrogenase | / | 0.449 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.448 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.448 | |
| 1swt | BTN | Streptavidin | / | 0.448 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.448 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.448 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.448 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.448 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.448 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.448 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.448 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.448 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.448 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.448 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.447 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.447 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.447 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.447 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.447 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.447 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.447 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.447 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.447 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.447 | |
| 3v2u | ATP | Protein GAL3 | / | 0.447 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.447 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.447 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.447 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.447 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.446 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.446 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 2ofi | ADK | 3-methyladenine DNA glycosylase I | / | 0.446 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.446 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.446 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.446 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.446 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.446 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.446 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.446 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.446 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.446 | |
| 4n1g | CEI | Obelin | / | 0.446 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.446 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.445 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.445 | |
| 2ohv | NHL | Glutamate racemase | / | 0.445 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.445 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.445 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.445 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.445 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.445 | |
| 4nhm | UN9 | Prolyl 3,4-dihydroxylase TPA1 | 1.14.11 | 0.445 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.445 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.445 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.445 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.445 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.444 | |
| 1c7o | PPG | Hemolysin | / | 0.444 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 1mzc | BNE | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.444 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.444 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.444 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.444 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.444 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.444 | |
| 4e31 | JHZ | Methyltransferase | / | 0.444 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.444 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.444 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.443 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.443 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1pyd | TDP | Pyruvate decarboxylase isozyme 1 | / | 0.443 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.443 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1t8x | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.443 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 1zji | 2PG | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.443 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.443 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
| 3e23 | SAM | Uncharacterized protein | / | 0.443 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.443 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.443 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.443 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.443 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.443 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.443 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.443 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.443 | |
| 4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.443 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 1n4q | LYS_CYS_VAL_ILE_LEU | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.442 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.442 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.442 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.442 | |
| 1zdw | FLV | Prenyltransferase | / | 0.442 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.442 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.442 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.442 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.442 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.442 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.442 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.442 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.442 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.442 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.441 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.441 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.441 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.441 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.441 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.441 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.441 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.441 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.441 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.441 | |
| 3ppr | 4CS | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.441 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4u7w | NDP | MxaA | / | 0.441 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.441 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.440 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.440 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.440 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.440 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.440 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.440 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.440 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.440 | |
| 3hdq | GDU | UDP-galactopyranose mutase | / | 0.440 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.440 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.440 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.440 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.440 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.440 | |
| 4isu | IKM | Glutamate receptor 2 | / | 0.440 | |
| 4jyz | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.440 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.440 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.440 |