sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4imp | NDP | Polyketide synthase extender modules 3-4 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 1.000 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.467 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.463 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.460 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.454 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.447 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4qec | NAP | ElxO | / | 0.446 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.445 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3sju | NDP | Keto reductase | / | 0.440 |