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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4iirANPSerine/threonine-protein kinase PRP4 homolog2.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4iirANPSerine/threonine-protein kinase PRP4 homolog2.7.11.11.000
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.558
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.548
4k33ACPFibroblast growth factor receptor 32.7.10.10.547
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.533
3dogNNNCyclin-dependent kinase 22.7.11.220.533
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.523
1u54ACPActivated CDC42 kinase 1/0.519
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.513
4gmy0X5Tyrosine-protein kinase JAK2/0.513
4o1pANPRibonuclease L/0.512
4j97ACPFibroblast growth factor receptor 2/0.509
2py3ACPFibroblast growth factor receptor 2/0.507
2cchATPCyclin-dependent kinase 22.7.11.220.505
5e92ANPTGF-beta receptor type-22.7.11.300.504
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.501
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.501
2x1nX1NCyclin-dependent kinase 22.7.11.220.499
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.499
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.498
1e9hINRCyclin-dependent kinase 22.7.11.220.497
4riyADPEpidermal growth factor receptor2.7.10.10.497
2pwlACPFibroblast growth factor receptor 2/0.496
4eol1ROCyclin-dependent kinase 22.7.11.220.496
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.495
3mtfA3FActivin receptor type-12.7.11.300.495
4bcnT9NCyclin-dependent kinase 22.7.11.220.494
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.494
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.494
1pkdUCNCyclin-dependent kinase 22.7.11.220.493
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.493
2izsBRQCasein kinase I isoform gamma-32.7.11.10.492
2pmlANPUncharacterized protein/0.492
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.491
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.491
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.490
1oguST8Cyclin-dependent kinase 22.7.11.220.489
2pz5ACPFibroblast growth factor receptor 2/0.489
2wihP48Cyclin-dependent kinase 22.7.11.220.489
3my5RFZCyclin-dependent kinase 22.7.11.220.489
4eoi1ROCyclin-dependent kinase 22.7.11.220.489
4eomATPCyclin-dependent kinase 22.7.11.220.489
4qmlANPSerine/threonine-protein kinase 242.7.11.10.489
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.488
3clyACPFibroblast growth factor receptor 2/0.487
3oriAGSSerine/threonine protein kinase/0.487
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.487
2iw84SPCyclin-dependent kinase 22.7.11.220.486
3axwTIDCasein kinase II subunit alpha2.7.11.10.486
2etm7PYFocal adhesion kinase 12.7.10.20.485
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.485
2uzdC85Cyclin-dependent kinase 22.7.11.220.485
2w1fL0FAurora kinase A2.7.11.10.485
4bbe3O4Tyrosine-protein kinase JAK2/0.485
1csnATPCasein kinase I homolog 12.7.11.10.484
1oiyN41Cyclin-dependent kinase 22.7.11.220.484
1qmzATPCyclin-dependent kinase 22.7.11.220.484
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.484
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.484
2uzbC75Cyclin-dependent kinase 22.7.11.220.484
1h1s4SPCyclin-dependent kinase 22.7.11.220.483
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.483
3ruqADPChaperonin/0.483
5eg3ACPFibroblast growth factor receptor 2/0.483
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.482
3wowANPCasein kinase II subunit alpha2.7.11.10.482
4eooATPCyclin-dependent kinase 22.7.11.220.482
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.481
2c4g514Cyclin-dependent kinase 22.7.11.220.481
2cjmATPCyclin-dependent kinase 22.7.11.220.481
3ttjJBIMitogen-activated protein kinase 102.7.11.240.481
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.481
2qo9ANPEphrin type-A receptor 32.7.10.10.480
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.480
4ez50RSCyclin-dependent kinase 62.7.11.220.480
2pzpACPFibroblast growth factor receptor 2/0.479
2w1gL0GAurora kinase A2.7.11.10.479
3ormAGSSerine/threonine protein kinase/0.479
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.478
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.478
4bgg844Activin receptor type-12.7.11.300.478
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.478
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.478
3hkoANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands/0.477
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.477
4i3zADPCyclin-dependent kinase 22.7.11.220.477
1h1r6CPCyclin-dependent kinase 22.7.11.220.476
1ir3ANPInsulin receptor2.7.10.10.476
3lq5SLQCyclin-dependent kinase 92.7.11.220.476
3oom507Activin receptor type-12.7.11.300.476
4ii5ADPCyclin-dependent kinase 22.7.11.220.476
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.476
1fvv107Cyclin-dependent kinase 22.7.11.220.475
1vyw292Cyclin-dependent kinase 22.7.11.220.475
2iw94SPCyclin-dependent kinase 22.7.11.220.475
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.475
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.475
5e8xSTUTGF-beta receptor type-12.7.11.300.475
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.474
3gu7ADPDeath-associated protein kinase 12.7.11.10.474
4bcmT7ZCyclin-dependent kinase 22.7.11.220.474
4btjADPTau-tubulin kinase 12.7.11.10.474
4btjATPTau-tubulin kinase 12.7.11.10.474
4j95ACPFibroblast growth factor receptor 2/0.474
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.474
3ddqRRCCyclin-dependent kinase 22.7.11.220.473
4eos1ROCyclin-dependent kinase 22.7.11.220.473
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.472
2pvyACPFibroblast growth factor receptor 2/0.472
3qqkX02Cyclin-dependent kinase 22.7.11.220.472
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.472
4ic7ANPMitogen-activated protein kinase 72.7.11.240.472
2y6o1N1Ephrin type-A receptor 42.7.10.10.471
3r73X87Cyclin-dependent kinase 22.7.11.220.471
4eor4SPCyclin-dependent kinase 22.7.11.220.471
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.471
4wkqIREEpidermal growth factor receptor2.7.10.10.471
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.471
2izuP01Casein kinase I isoform gamma-32.7.11.10.470
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.470
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
3r1yX76Cyclin-dependent kinase 22.7.11.220.470
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.470
2itnANPEpidermal growth factor receptor2.7.10.10.469
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.469
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.469
4bcoT6QCyclin-dependent kinase 22.7.11.220.469
4jia1K3Tyrosine-protein kinase JAK2/0.469
5cvfATPCasein kinase II subunit alpha2.7.11.10.469
2qoqANPEphrin type-A receptor 32.7.10.10.468
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
3vjnANPEpidermal growth factor receptor2.7.10.10.468
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.468
4c57FEFCyclin-G-associated kinase2.7.11.10.468
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.468
5awmANPStress-activated protein kinase JNK2.7.11.240.468
1pyePM1Cyclin-dependent kinase 22.7.11.220.467
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
2f2cAP9Cyclin-dependent kinase 62.7.11.220.467
3ddpRC8Cyclin-dependent kinase 22.7.11.220.467
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.467
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.467
4dgo0JWCasein kinase II subunit alpha2.7.11.10.467
4hgt15GCasein kinase I isoform delta2.7.11.10.467
5drdATPAurora kinase A2.7.11.10.467
1g6cTZPThiamine-phosphate synthase/0.466
2henADPEphrin type-B receptor 22.7.10.10.466
2rghFADAlpha-Glycerophosphate Oxidase/0.466
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.466
4dgnLU2Casein kinase II subunit alpha2.7.11.10.466
4fx360KCyclin-dependent kinase 22.7.11.220.466
4gk3L87Ephrin type-A receptor 32.7.10.10.466
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.466
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
2vu3LZECyclin-dependent kinase 22.7.11.220.465
3cgbCOACoenzyme A disulfide reductase/0.465
3ezrEZRCyclin-dependent kinase 22.7.11.220.465
4deaNHIAurora kinase A2.7.11.10.465
4hvi19STyrosine-protein kinase JAK32.7.10.20.465
2c9cATPPsp operon transcriptional activator/0.464
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
2zjwREFCasein kinase II subunit alpha2.7.11.10.464
3at4CCKCasein kinase II subunit alpha2.7.11.10.464
3bhtMFRCyclin-dependent kinase 22.7.11.220.464
3ggfGVDSerine/threonine-protein kinase 26/0.464
3q9xEMOCasein kinase II subunit alpha2.7.11.10.464
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.464
5e8wSTUTGF-beta receptor type-12.7.11.300.464
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.463
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.463
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.463
2xp2VGHALK tyrosine kinase receptor2.7.10.10.463
3cgdCOACoenzyme A disulfide reductase/0.463
3lpbNVBTyrosine-protein kinase JAK2/0.463
3miaANPCyclin-dependent kinase 92.7.11.220.463
3r7iX9ICyclin-dependent kinase 22.7.11.220.463
4bcpT3CCyclin-dependent kinase 22.7.11.220.463
4jrnANPRhoptry kinase family protein/0.463
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.463
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.462
2np8CC3Aurora kinase A2.7.11.10.462
3rak03ZCyclin-dependent kinase 22.7.11.220.462
3s1cZIRCytokinin dehydrogenase 11.5.99.120.462
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4qmySTUSerine/threonine-protein kinase 242.7.11.10.462
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.461
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.461
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.461
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.461
2xs0ANPMitogen-activated protein kinase 82.7.11.240.461
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3blqATPCyclin-dependent kinase 92.7.11.220.461
3iok1P6Tyrosine-protein kinase JAK2/0.461
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.461
4b99R4LMitogen-activated protein kinase 72.7.11.240.461
4gu94GUFocal adhesion kinase 12.7.10.20.461
4jboWPHAurora kinase A2.7.11.10.461
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.461
4zseANPEpidermal growth factor receptor2.7.10.10.461
5auwQUEDeath-associated protein kinase 12.7.11.10.461
1cqp803Integrin alpha-L/0.460
1jstATPCyclin-dependent kinase 22.7.11.220.460
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.460
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.460
2qo7ANPEphrin type-A receptor 32.7.10.10.460
3hmm855TGF-beta receptor type-12.7.11.300.460
3rm618ZCyclin-dependent kinase 22.7.11.220.460
3tnwF18Cyclin-dependent kinase 22.7.11.220.460
4bchT7ZCyclin-dependent kinase 92.7.11.220.460
4hvh19RTyrosine-protein kinase JAK32.7.10.20.460
4k8aK8AFocal adhesion kinase 12.7.10.20.460
5cshATPCasein kinase II subunit alpha2.7.11.10.460
5dn3ATPAurora kinase A2.7.11.10.460
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.459
1v0oINRCell division control protein 2 homolog2.7.11.220.459
2bkzSBCCyclin-dependent kinase 22.7.11.220.459
2ituITQEpidermal growth factor receptor2.7.10.10.459
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.459
2v7a627Tyrosine-protein kinase ABL12.7.10.20.459
2vwiANPSerine/threonine-protein kinase OSR12.7.11.10.459
2wotZZGTGF-beta receptor type-12.7.11.300.459
3rpo24ZCyclin-dependent kinase 22.7.11.220.459
4eop1ROCyclin-dependent kinase 22.7.11.220.459
4xlvACPInsulin receptor2.7.10.10.459
4yswFADXanthine dehydrogenase/oxidase/0.459
5dpvSKEAurora kinase A2.7.11.10.459
1lp4ANPCasein kinase II subunit alpha2.7.11.10.458
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.458
1oi9N20Cyclin-dependent kinase 22.7.11.220.458
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.458
2b1pAIZMitogen-activated protein kinase 102.7.11.240.458
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.458
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.458
3dds26BGlycogen phosphorylase, liver form2.4.1.10.458
3r7vZ02Cyclin-dependent kinase 22.7.11.220.458
4jqeANPCasein kinase II subunit alpha2.7.11.10.458
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.458
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.457
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.457
2c96ATPPsp operon transcriptional activator/0.457
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.457
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.457
3pj8404Cyclin-dependent kinase 22.7.11.220.457
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.457
5cnnANPEpidermal growth factor receptor2.7.10.10.457
5dnrATPAurora kinase A2.7.11.10.457
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
2w05FRTCyclin-dependent kinase 22.7.11.220.456
3gu6ADPDeath-associated protein kinase 12.7.11.10.456
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.456
5e8ySTUTGF-beta receptor type-22.7.11.300.456
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
1i44ACPInsulin receptor2.7.10.10.455
2eufLQQCyclin-dependent kinase 62.7.11.220.455
2itzIREEpidermal growth factor receptor2.7.10.10.455
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.455
3vryB43Tyrosine-protein kinase HCK2.7.10.20.455
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.455
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.455
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.455
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.455
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.455
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.455
5aaaVGHALK tyrosine kinase receptor2.7.10.10.455
1dawANPCasein kinase II subunit alpha2.7.11.10.454
1oiuN76Cyclin-dependent kinase 22.7.11.220.454
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.454
2btsU32Cyclin-dependent kinase 22.7.11.220.454
2csnCKICasein kinase I homolog 12.7.11.10.454
2j0m4STFocal adhesion kinase 12.7.10.20.454
2vttLZDCyclin-dependent kinase 22.7.11.220.454
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.454
3c4zADPRhodopsin kinase/0.454
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.454
4eon1ROCyclin-dependent kinase 22.7.11.220.454
4zohFADPutative oxidoreductase FAD-binding subunit/0.454
1eh4IC1Casein kinase I homolog 12.7.11.10.453
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.453
2c5nCK8Cyclin-dependent kinase 22.7.11.220.453
2c6tDT5Cyclin-dependent kinase 22.7.11.220.453
2i40BLZCyclin-dependent kinase 22.7.11.220.453
2uzeC95Cyclin-dependent kinase 22.7.11.220.453
2xa4AZ5Tyrosine-protein kinase JAK2/0.453
3emg685Tyrosine-protein kinase SYK2.7.10.20.453
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.453
4bcqTJFCyclin-dependent kinase 22.7.11.220.453
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.453
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.453
1om1IQACasein kinase II subunit alpha2.7.11.10.452
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.452
2vkvTDCTetracycline repressor protein class D/0.452
2w17I19Cyclin-dependent kinase 22.7.11.220.452
2zbaZBATrichothecene 3-O-acetyltransferase/0.452
2zdt46CMitogen-activated protein kinase 102.7.11.240.452
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3orlAGSSerine/threonine protein kinase/0.452
3qzhX69Cyclin-dependent kinase 22.7.11.220.452
3rpv26ZCyclin-dependent kinase 22.7.11.220.452
3uwqU5POrotidine 5'-phosphate decarboxylase/0.452
3w16P9JAurora kinase A2.7.11.10.452
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.452
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.451
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.451
2itqITQEpidermal growth factor receptor2.7.10.10.451
2izrBRKCasein kinase I isoform gamma-32.7.11.10.451
2pvnP63Casein kinase II subunit alpha2.7.11.10.451
2w1dL0DAurora kinase A2.7.11.10.451
2xuuADPDeath-associated protein kinase 12.7.11.10.451
2zdu446Mitogen-activated protein kinase 102.7.11.240.451
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.451
3eljGS7Mitogen-activated protein kinase 82.7.11.240.451
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
3l8p0CEAngiopoietin-1 receptor2.7.10.10.451
3lltANPProtein serine/threonine kinase-1/0.451
3nszANPCasein kinase II subunit alpha2.7.11.10.451
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.451
3r7yZ04Cyclin-dependent kinase 22.7.11.220.451
3t8oATPRhodopsin kinase/0.451
4f7l0SOCyclin-dependent kinase 82.7.11.220.451
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.451
4grb0XGCasein kinase II subunit alpha2.7.11.10.451
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.451
4ix5ANPUncharacterized protein/0.451
4jr7GNPCasein kinase II subunit alpha2.7.11.10.451
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.450
2itpAEEEpidermal growth factor receptor2.7.10.10.450
2itvANPEpidermal growth factor receptor2.7.10.10.450
2o0uC0MMitogen-activated protein kinase 102.7.11.240.450
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.450
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4i8vBHFCytochrome P450 1A11.14.14.10.450
4ix4ADPUncharacterized protein/0.450
4ix6ADPUncharacterized protein/0.450
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.450
4ogrADNCyclin-dependent kinase 92.7.11.220.450
5aacVGHALK tyrosine kinase receptor2.7.10.10.450
1gih1PUCyclin-dependent kinase 22.7.11.220.449
1nzdUPGDNA beta-glucosyltransferase/0.449
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.449
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.449
2ckeIQUDeath-associated protein kinase 2/0.449
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.449
2p33J07Mitogen-activated protein kinase 102.7.11.240.449
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.449
3c13EMOCasein kinase II subunit alpha2.7.11.10.449
3c50ADPRhodopsin kinase/0.449
3kvxFMYMitogen-activated protein kinase 102.7.11.240.449
3ql8X01Cyclin-dependent kinase 22.7.11.220.449
3v3vMYUMitogen-activated protein kinase 82.7.11.240.449
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.449
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.449
4e4m0NHTyrosine-protein kinase JAK2/0.449
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.449
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.449
4hgs15GCasein kinase I isoform gamma-32.7.11.10.449
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.449
1cm8ANPMitogen-activated protein kinase 12/0.448
1ol7ADPAurora kinase A2.7.11.10.448
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.448
2c5yMTWCyclin-dependent kinase 22.7.11.220.448
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.448
2vv9IM9Cyclin-dependent kinase 22.7.11.220.448
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.448
3ibqATPPyridoxal kinase/0.448
3nbwTR4Ketohexokinase/0.448
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.448
4cfnJYMCyclin-dependent kinase 22.7.11.220.448
4dieC5PCytidylate kinase/0.448
4eok4SPCyclin-dependent kinase 22.7.11.220.448
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.448
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.448
4j1tNADNAD/NADP transhydrogenase alpha subunit 1/0.448
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.448
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.447
1h1pCMGCyclin-dependent kinase 22.7.11.220.447
1p2a5BNCyclin-dependent kinase 22.7.11.220.447
1q3qANPThermosome subunit alpha/0.447
1tvoFRZMitogen-activated protein kinase 12.7.11.240.447
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.447
2bx8AZQSerum albumin/0.447
2cciATPCyclin-dependent kinase 22.7.11.220.447
2uzlC94Cyclin-dependent kinase 22.7.11.220.447
2vtqLZACyclin-dependent kinase 22.7.11.220.447
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.447
3r7eX88Cyclin-dependent kinase 22.7.11.220.447
3r9hZ67Cyclin-dependent kinase 22.7.11.220.447
3vs3VSETyrosine-protein kinase HCK2.7.10.20.447
3w2sW2REpidermal growth factor receptor2.7.10.10.447
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.447
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4dymIYZActivin receptor type-12.7.11.300.447
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
4o4eATPKinase/0.447
1dayGNPCasein kinase II subunit alpha2.7.11.10.446
1jpaANPEphrin type-B receptor 22.7.10.10.446
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.446
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.446
2vwx7X4Ephrin type-B receptor 42.7.10.10.446
2xru400Aurora kinase A2.7.11.10.446
2yn8STUEphrin type-B receptor 42.7.10.10.446
2z7lS91Mitogen-activated protein kinase 12.7.11.240.446
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.446
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.446
4bbfO19Tyrosine-protein kinase JAK2/0.446
4fvqATPTyrosine-protein kinase JAK2/0.446
4o4fATPKinase/0.446
5cb4ACPTubulin tyrosine ligase/0.446
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.445
1og6NAPOxidoreductase YdhF10.445
1pjkANPCasein kinase II subunit alpha2.7.11.10.445
1rw8580TGF-beta receptor type-12.7.11.300.445
2vgoAD5Aurora kinase B-A2.7.11.10.445
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.445
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.445
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.445
4btmF8ETau-tubulin kinase 12.7.11.10.445
4c58824Cyclin-G-associated kinase2.7.11.10.445
4fmqANPMitogen-activated protein kinase 12.7.11.240.445
4lyn1YGCyclin-dependent kinase 22.7.11.220.445
4r1lADPPhenylacetate-coenzyme A ligase/0.445
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.444
1vjy460TGF-beta receptor type-12.7.11.300.444
1xjdSTUProtein kinase C theta type2.7.11.130.444
2bhhRYUCyclin-dependent kinase 22.7.11.220.444
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.444
2hk51BMTyrosine-protein kinase HCK2.7.10.20.444
2hog710Serine/threonine-protein kinase Chk12.7.11.10.444
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.444
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.444
2wpa889Cyclin-dependent kinase 22.7.11.220.444
3a7jADPSerine/threonine-protein kinase 242.7.11.10.444
3be9P04Casein kinase II subunit alpha2.7.11.10.444
3bheBZNGag-Pol polyprotein3.4.23.160.444
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.444
3qc9ADPRhodopsin kinase/0.444
3r8pZ46Cyclin-dependent kinase 22.7.11.220.444
3r9dX6BCyclin-dependent kinase 22.7.11.220.444
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.444
3w32W32Epidermal growth factor receptor2.7.10.10.444
4anmWULCasein kinase II subunit alpha2.7.11.10.444
4cd0AWJALK tyrosine kinase receptor2.7.10.10.444
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.444
4erwSTUCyclin-dependent kinase 22.7.11.220.444
4fkw62KCyclin-dependent kinase 22.7.11.220.444
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.444
4g170VNCasein kinase I isoform gamma-32.7.11.10.444
4i22IREEpidermal growth factor receptor2.7.10.10.444
4nj32KDCyclin-dependent kinase 22.7.11.220.444
4nks2M2Fibroblast growth factor receptor 1/0.444
4ocvANPAminoglycoside phosphotransferase/0.444
4u03GTPCyclic GMP-AMP synthase/0.444
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
5av2KMPDeath-associated protein kinase 12.7.11.10.444
1g5sI17Cyclin-dependent kinase 22.7.11.220.443
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.443
1m2qMNXCasein kinase II subunit alpha2.7.11.10.443
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.443
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.443
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2j7t274Serine/threonine-protein kinase 102.7.11.10.443
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.443
2xvdAS6Ephrin type-B receptor 42.7.10.10.443
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.443
3oibFDAPutative acyl-CoA dehydrogenase/0.443
3poz03PEpidermal growth factor receptor2.7.10.10.443
3qx2X63Cyclin-dependent kinase 22.7.11.220.443
3w33W19Epidermal growth factor receptor2.7.10.10.443
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.443
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.443
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.442
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.442
2pvlP55Casein kinase II subunit alpha2.7.11.10.442
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.442
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.442
3i60E86Mitogen-activated protein kinase 12.7.11.240.442
3nbvANPKetohexokinase/0.442
3pe2E1BCasein kinase II subunit alpha2.7.11.10.442
3rm719ZCyclin-dependent kinase 22.7.11.220.442
3s0o50ZCyclin-dependent kinase 22.7.11.220.442
3sqq99ZCyclin-dependent kinase 22.7.11.220.442
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4enhFVXCholesterol 24-hydroxylase/0.442
4fkv61KCyclin-dependent kinase 22.7.11.220.442
4foc0UUALK tyrosine kinase receptor2.7.10.10.442
4fod0UVALK tyrosine kinase receptor2.7.10.10.442
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4m4922YL-lactate dehydrogenase A chain1.1.1.270.442
4o0uADNAurora kinase A2.7.11.10.442
4q5hANPProtein kinase OspG2.70.442
5auvAGIDeath-associated protein kinase 12.7.11.10.442
5ce3ADPProtein kinase YopO/0.442
1aj8COACitrate synthase/0.441
1bygSTUTyrosine-protein kinase CSK/0.441
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.441
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.441
1yvj4STTyrosine-protein kinase JAK32.7.10.20.441
2bfyH1NAurora kinase B-A2.7.11.10.441
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.441
2ittAEEEpidermal growth factor receptor2.7.10.10.441
2pd7FADVivid PAS protein VVD/0.441
2xh9J01Uncharacterized protein/0.441
2yxuATPPyridoxal kinase2.7.1.350.441
3iggEFQCyclin-dependent kinase 22.7.11.220.441
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.441
3ortAGSSerine/threonine protein kinase/0.441
3qdd94MHeat shock protein HSP 90-alpha/0.441
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.441
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.441
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
5c8yACPTubulin tyrosine ligase/0.441
5fwnNAPPutative dehydrogenase/0.441
2j0lANPFocal adhesion kinase 12.7.10.20.440
2w06FRVCyclin-dependent kinase 22.7.11.220.440
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.440
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.440
3js2VM1Fibroblast growth factor receptor 1/0.440
3nux3NVCyclin-dependent kinase 62.7.11.220.440
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.440
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.440
3qqfX07Cyclin-dependent kinase 22.7.11.220.440
3ttiKBIMitogen-activated protein kinase 102.7.11.240.440
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.440
4ccbOFGALK tyrosine kinase receptor2.7.10.10.440
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.440
4gncASORegucalcin3.1.1.170.440
4k2rANPTyrosine-protein kinase ZAP-702.7.10.20.440
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.440
4l9i8PRRhodopsin kinase/0.440
5dt3ATPAurora kinase A2.7.11.10.440