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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ii5ADPCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4ii5ADPCyclin-dependent kinase 22.7.11.221.000
4eooATPCyclin-dependent kinase 22.7.11.220.547
4i3zADPCyclin-dependent kinase 22.7.11.220.541
1qmzATPCyclin-dependent kinase 22.7.11.220.522
3my5RFZCyclin-dependent kinase 22.7.11.220.462
4qnyANPMitogen activated protein kinase, putative/0.456
2uzbC75Cyclin-dependent kinase 22.7.11.220.451
4bcmT7ZCyclin-dependent kinase 22.7.11.220.449
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.443
2cjmATPCyclin-dependent kinase 22.7.11.220.443