sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4i9i	1DY	Tankyrase-1	2.4.2.30

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4i9i	1DY	Tankyrase-1	2.4.2.30	1.000
4bj9	UHB	Tankyrase-2	2.4.2.30	0.552
4li6	1XO	Tankyrase-1	2.4.2.30	0.542
4bfp	SWY	Tankyrase-2	2.4.2.30	0.531
4hyf	1AK	Tankyrase-2	2.4.2.30	0.526
4k4e	K4E	Tankyrase-1	2.4.2.30	0.521
4msk	2C8	Tankyrase-1	2.4.2.30	0.515
4mt9	2D6	Tankyrase-1	2.4.2.30	0.513
4li8	1XQ	Tankyrase-1	2.4.2.30	0.504
4pnm	NU1	Tankyrase-2	2.4.2.30	0.493
4li7	1XP	Tankyrase-1	2.4.2.30	0.484
4tkg	09L	Tankyrase-2	2.4.2.30	0.478
3u9y	09L	Tankyrase-2	2.4.2.30	0.473
4krs	1SX	Tankyrase-1	2.4.2.30	0.469
4tjy	3GN	Tankyrase-2	2.4.2.30	0.462
4msg	2C6	Tankyrase-1	2.4.2.30	0.452
4n4v	2GY	Tankyrase-1	2.4.2.30	0.452
4n4t	2GV	Tankyrase-1	2.4.2.30	0.448
4pnr	G18	Tankyrase-2	2.4.2.30	0.440