sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4i0a	CMP	cAMP-activated global transcriptional regulator CRP

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4i0a	CMP	cAMP-activated global transcriptional regulator CRP	/	1.000
3ryp	CMP	cAMP-activated global transcriptional regulator CRP	/	0.692
2gzw	CMP	cAMP-activated global transcriptional regulator CRP	/	0.635
1i5z	CMP	cAMP-activated global transcriptional regulator CRP	/	0.606
4hzf	CMP	cAMP-activated global transcriptional regulator CRP	/	0.603
4i09	CMP	cAMP-activated global transcriptional regulator CRP	/	0.600
3kcc	CMP	cAMP-activated global transcriptional regulator CRP	/	0.595
4i01	CMP	cAMP-activated global transcriptional regulator CRP	/	0.561
4i0b	CMP	cAMP-activated global transcriptional regulator CRP	/	0.543
1i6x	CMP	cAMP-activated global transcriptional regulator CRP	/	0.516
1cgp	CMP	cAMP-activated global transcriptional regulator CRP	/	0.509
4ft8	CMP	cAMP-activated global transcriptional regulator CRP	/	0.497
1zrc	CMP	cAMP-activated global transcriptional regulator CRP	/	0.485
1ruo	CMP	cAMP-activated global transcriptional regulator CRP	/	0.476
3rou	CMP	cAMP-activated global transcriptional regulator CRP	/	0.472
4r8h	SP1	cAMP-activated global transcriptional regulator CRP	/	0.461
1zrd	CMP	cAMP-activated global transcriptional regulator CRP	/	0.457
3rpq	CMP	cAMP-activated global transcriptional regulator CRP	/	0.456