sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4hyf	1AK	Tankyrase-2	2.4.2.30

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4hyf	1AK	Tankyrase-2	2.4.2.30	1.000
4li6	1XO	Tankyrase-1	2.4.2.30	0.560
4mt9	2D6	Tankyrase-1	2.4.2.30	0.546
4li8	1XQ	Tankyrase-1	2.4.2.30	0.541
4li7	1XP	Tankyrase-1	2.4.2.30	0.536
4bj9	UHB	Tankyrase-2	2.4.2.30	0.532
4k4e	K4E	Tankyrase-1	2.4.2.30	0.532
4msk	2C8	Tankyrase-1	2.4.2.30	0.524
4pnm	NU1	Tankyrase-2	2.4.2.30	0.521
4bfp	SWY	Tankyrase-2	2.4.2.30	0.517
4i9i	1DY	Tankyrase-1	2.4.2.30	0.510
4n4v	2GY	Tankyrase-1	2.4.2.30	0.503
4tkg	09L	Tankyrase-2	2.4.2.30	0.497
4msg	2C6	Tankyrase-1	2.4.2.30	0.487
3u9y	09L	Tankyrase-2	2.4.2.30	0.476
4n4t	2GV	Tankyrase-1	2.4.2.30	0.472
4tjy	3GN	Tankyrase-2	2.4.2.30	0.469
4krs	1SX	Tankyrase-1	2.4.2.30	0.454
4k4f	K4F	Tankyrase-1	2.4.2.30	0.444