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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4hxs1A3Bromodomain-containing protein 4

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4hxs1A3Bromodomain-containing protein 4/1.000
4hxn1A7Bromodomain-containing protein 4/0.812
4hby13FBromodomain-containing protein 4/0.667
4hxr1A4Bromodomain-containing protein 4/0.656
4c67L5SBromodomain-containing protein 4/0.652
4lrg1XBBromodomain-containing protein 4/0.639
4lr61XABromodomain-containing protein 4/0.635
4bw39BMBromodomain-containing protein 4/0.633
4j0s1H3Bromodomain-containing protein 4/0.628
4men25KBromodomain-containing protein 4/0.618
4a9oA9OBromodomain-containing protein 2/0.616
4hxo1A6Bromodomain-containing protein 4/0.616
4nqmY1ZBromodomain-containing protein 4/0.615
2yelWSHBromodomain-containing protein 4/0.614
4bjx73BBromodomain-containing protein 4/0.613
4c66H4CBromodomain-containing protein 4/0.609
4a9lP9LBromodomain-containing protein 4/0.606
4o701QKBromodomain-containing protein 4/0.605
4ogiR78Bromodomain-containing protein 4/0.602
4mr41K0Bromodomain-containing protein 4/0.599
4qzsJQ1Bromodomain-containing protein 4/0.599
4j0r1H2Bromodomain-containing protein 4/0.598
4meq25OBromodomain-containing protein 4/0.595
3aqaBYHBromodomain-containing protein 2/0.592
4a9nA9NBromodomain-containing protein 2/0.592
4bw1S5BBromodomain-containing protein 4/0.591
4uyf73BBromodomain-containing protein 2/0.591
4bw2UTHBromodomain-containing protein 4/0.587
4flpJQ1Bromodomain testis-specific protein/0.586
4mep24YBromodomain-containing protein 4/0.586
4o74R78Bromodomain-containing protein 4/0.582
4uyg73BBromodomain-containing protein 2/0.582
2ydwWSHBromodomain-containing protein 2/0.581
4alhA9PBromodomain-containing protein 2/0.579
3zyu1GHBromodomain-containing protein 4/0.578
4aknS5BBromodomain-containing protein 2/0.578
4lyw21QBromodomain-containing protein 4/0.577
4hbw14ZBromodomain-containing protein 4/0.574
4j3i1K0Bromodomain-containing protein 4/0.564
4o71CPBBromodomain-containing protein 4/0.564
4a9mP9MBromodomain-containing protein 2/0.560
2yemWSHBromodomain-containing protein 4/0.554
4f3i0S6Bromodomain-containing protein 4/0.554
4mr61K0Bromodomain-containing protein 2/0.554
4bw49B6Bromodomain-containing protein 4/0.548
4cfl8DQBromodomain-containing protein 4/0.545
4o78SAVBromodomain-containing protein 4/0.545
4j1p1K0Bromodomain-containing protein 2/0.543
4alg1GHBromodomain-containing protein 2/0.540
4a9iP9IBromodomain-containing protein 2/0.539
4nr52LLCREB-binding protein/0.539
2yekEAMBromodomain-containing protein 2/0.526
4py6R78Bromodomain protein, putative/0.525
4cfkLY2Bromodomain-containing protein 4/0.524
4meo25VBromodomain-containing protein 4/0.522
4gpj0Q1Bromodomain-containing protein 4/0.519
5bt52LOBromodomain-containing protein 2/0.519
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.515
4nmbFADBifunctional protein PutA/0.507
4hxm1A8Bromodomain-containing protein 4/0.506
3d84NDPDihydrofolate reductase1.5.1.30.504
4mr51K0Bromodomain-containing protein 2/0.499
3qlrNDPDihydrofolate reductase1.5.1.30.498
3svgODRBromodomain-containing protein 4/0.497
1m78NDPDihydrofolate reductase1.5.1.30.496
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.494
1rx8FOLDihydrofolate reductase1.5.1.30.492
3cyz9ODPheromone-binding protein ASP1/0.491
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.490
3nxxNDPDihydrofolate reductase1.5.1.30.489
4fhi0S4Vitamin D3 receptor A/0.488
3vt7VDXVitamin D3 receptor/0.485
1dr3TAPDihydrofolate reductase1.5.1.30.483
3b9lAZZSerum albumin/0.483
3ia4MTXDihydrofolate reductase/0.483
3nglNAPBifunctional protein FolD/0.483
3nr4PYVAbscisic acid receptor PYL2/0.483
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.483
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.482
3lqfNADGalactitol dehydrogenase/0.482
2puiADPMethylthioribose kinase2.7.1.1000.481
4b4oNDPEpimerase family protein SDR39U1/0.481
3pqbVGPPutative oxidoreductase/0.480
3c3dFO12-phospho-L-lactate transferase/0.479
3cgeCOACoenzyme A disulfide reductase/0.479
1vj3TABDihydrofolate reductase1.5.1.30.478
4mv8ACPBiotin carboxylase6.3.4.140.478
1ai9NDPDihydrofolate reductase1.5.1.30.477
1dr3HBIDihydrofolate reductase1.5.1.30.477
4ap3FADSteroid monooxygenase/0.477
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.477
4nr82LLBromodomain-containing protein 4/0.477
2ovhAS0Progesterone receptor/0.476
3k47D09Dihydrofolate reductase1.5.1.30.476
3vt8YI3Vitamin D3 receptor/0.476
4c02TAKActivin receptor type-12.7.11.300.476
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.476
4nyv15ECREB-binding protein/0.475
4wa9AXITyrosine-protein kinase ABL12.7.10.20.475
1x8lOXRRetinol dehydratase/0.474
1ykdCMPAdenylate cyclase/0.474
2po7CHDFerrochelatase, mitochondrial4.99.1.10.474
3tk3CPZCytochrome P450 2B41.14.14.10.474
4ir5IR5Bromodomain adjacent to zinc finger domain protein 2B/0.474
1ia4TQ6Dihydrofolate reductase1.5.1.30.473
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
3cz09ODPheromone-binding protein ASP1/0.473
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.473
4erf0R3E3 ubiquitin-protein ligase Mdm26.3.20.473
5cshATPCasein kinase II subunit alpha2.7.11.10.473
2j9gANPBiotin carboxylase6.3.4.140.472
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.472
3mykANPMyosin-2 heavy chain/0.472
4j6dTESCytochrome P450 monooxygenase/0.472
1r2jFADFkbI/0.471
1uy6PU3Heat shock protein HSP 90-alpha/0.471
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.471
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.471
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.471
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.471
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
4elb34RDihydrofolate reductase/0.471
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
1cqp803Integrin alpha-L/0.470
1ia3TQ5Dihydrofolate reductase1.5.1.30.470
3cseN22Uncharacterized protein/0.470
3reyXACAdenosine receptor A2a/0.470
2nn7M29Carbonic anhydrase 14.2.1.10.469
3ctj320Hepatocyte growth factor receptor2.7.10.10.469
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.469
3qlzQLZUncharacterized protein/0.469
3srqQ19Dihydrofolate reductase1.5.1.30.469
2xvv9DNSerum albumin/0.468
3eek53SUncharacterized protein/0.468
3p3zP3ZPutative cytochrome P450/0.468
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
4ejh0QACytochrome P450 2A131.14.14.10.468
4g2rH1LProbable propionyl-CoA carboxylase beta chain 66.4.1.30.468
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.468
4jboWPHAurora kinase A2.7.11.10.468
4r1lADPPhenylacetate-coenzyme A ligase/0.468
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.467
4eos1ROCyclin-dependent kinase 22.7.11.220.467
4fgg0U5Dihydrofolate reductase1.5.1.30.467
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.467
4kwi1TJReductase homolog/0.467
4mwhATPCasein kinase II subunit alpha2.7.11.10.467
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
2qboCAMCamphor 5-monooxygenase1.14.15.10.466
3dleGFAGag-Pol polyprotein2.7.7.490.466
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.466
4dgo0JWCasein kinase II subunit alpha2.7.11.10.466
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.466
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.466
1kqwRTLCellular retinol-binding protein type II/0.465
1s3vTQDDihydrofolate reductase1.5.1.30.465
2ovmAS0Progesterone receptor/0.465
2w3vTOPDihydrofolate reductase/0.465
2ylxFADPhenylacetone monooxygenase1.14.13.920.465
3a783EVVitamin D3 receptor/0.465
3hz142CHeat shock protein HSP 90-alpha/0.465
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.465
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.465
1rx1NAPDihydrofolate reductase1.5.1.30.464
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
2bxmIMNSerum albumin/0.464
2h96893Mitogen-activated protein kinase 82.7.11.240.464
3s79ASDAromatase1.14.14.140.464
1tduDURThymidylate synthase/0.463
2bxqIMNSerum albumin/0.463
2jn3JN3Fatty acid-binding protein, liver/0.463
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.463
3axwTIDCasein kinase II subunit alpha2.7.11.10.463
3cgcCOACoenzyme A disulfide reductase/0.463
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.463
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.463
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.463
3v9y24LPeroxisome proliferator-activated receptor gamma/0.463
4g2gTDHMycocyclosin synthase1.14.21.90.463
4i8vBHFCytochrome P450 1A11.14.14.10.463
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1itzTPPTransketolase, chloroplastic2.2.1.10.462
1tvrTB9Gag-Pol polyprotein2.7.7.490.462
2qk8MTXDihydrofolate reductase/0.462
2z3uCRRCytochrome P450/0.462
3hz137DHeat shock protein HSP 90-alpha/0.462
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.462
4ryvZEAProtein LlR18A/0.462
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.461
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.461
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.461
2l98STLTroponin C, slow skeletal and cardiac muscles/0.461
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.461
2w9hTOPDihydrofolate reductase1.5.1.30.461
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.461
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.461
3oafOAGDihydrofolate reductase1.5.1.30.461
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.461
3vt9YI4Vitamin D3 receptor/0.461
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4i22IREEpidermal growth factor receptor2.7.10.10.461
4ia3BIVVitamin D3 receptor A/0.461
4iteTEYVitamin D3 receptor/0.461
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.460
2z2w770Wee1-like protein kinase2.7.10.20.460
3gwfNAPCyclohexanone monooxygenase/0.460
3inwJZBHeat shock protein HSP 90-alpha/0.460
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.460
3vrwYS5Vitamin D3 receptor/0.460
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4dpwAGSMevalonate diphosphate decarboxylase/0.460
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4g2fC07Ephrin type-A receptor 32.7.10.10.460
4ia1BIVVitamin D3 receptor A/0.460
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.460
1mp0NADAlcohol dehydrogenase class-31.1.1.10.459
1ndzFR5Adenosine deaminase3.5.4.40.459
1rkhVD2Vitamin D3 receptor/0.459
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
2hcdBIVVitamin D3 receptor A/0.459
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.459
3h4vNAPPteridine reductase 11.5.1.330.459
3ibqATPPyridoxal kinase/0.459
3ns2PYVAbscisic acid receptor PYL2/0.459
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.459
3vt5YI2Vitamin D3 receptor/0.459
4awo99BHeat shock protein HSP 90-alpha/0.459
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.459
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.459
4cdmFO1Deoxyribodipyrimidine photolyase/0.459
4fehFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.459
4hnc0UTMandelate racemase/0.459
4iarERM5-hydroxytryptamine receptor 1B/0.459
4nyw2O3CREB-binding protein/0.459
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.459
1klkPMDDihydrofolate reductase1.5.1.30.458
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2hamC33Vitamin D3 receptor/0.458
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.458
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.458
2xvw9NRSerum albumin/0.458
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.458
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.458
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.458
4fi1ATPCasein kinase II subunit alpha2.7.11.10.458
4g47TZFMycocyclosin synthase1.14.21.90.458
4ia2BIVVitamin D3 receptor A/0.458
1bwsNDPGDP-L-fucose synthase/0.457
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.457
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1ia1NDPDihydrofolate reductase1.5.1.30.457
2hasC3OVitamin D3 receptor/0.457
2vnaNAPProstaglandin reductase 21.3.1.480.457
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.457
2w6zL21Biotin carboxylase6.3.4.140.457
2xlsFADPutative flavin-containing monooxygenase/0.457
2zbaZBATrichothecene 3-O-acetyltransferase/0.457
3bfb9ODPheromone-binding protein ASP1/0.457
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.457
3h18PMSEsterase/lipase/0.457
4dgnLU2Casein kinase II subunit alpha2.7.11.10.457
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.457
4kak06UDihydrofolate reductase1.5.1.30.457
4kl9NDPDihydrofolate reductase1.5.1.30.457
4kwhNAPReductase homolog/0.457
4pkl1GHUncharacterized protein/0.457
1dhiMTXDihydrofolate reductase1.5.1.30.456
1diuBDMDihydrofolate reductase1.5.1.30.456
1pl8NADSorbitol dehydrogenase1.1.1.140.456
1rx8NAPDihydrofolate reductase1.5.1.30.456
1s19MC9Vitamin D3 receptor/0.456
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.456
2bunFADAppA protein/0.456
2o4rVD5Vitamin D3 receptor/0.456
2qblCAMCamphor 5-monooxygenase1.14.15.10.456
2tpsTPSThiamine-phosphate synthase/0.456
2wi72KLHeat shock protein HSP 90-alpha/0.456
2znpK55Peroxisome proliferator-activated receptor delta/0.456
3mdvCL6Cholesterol 24-hydroxylase/0.456
3p8iFMNPentaerythritol tetranitrate reductase/0.456
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.456
3w0aDS5Vitamin D3 receptor/0.456
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.456
4awp99AHeat shock protein HSP 90-alpha/0.456
4dijBLFE3 ubiquitin-protein ligase Mdm26.3.20.456
4g1y0VOVitamin D3 receptor A/0.456
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.456
4ips1G4Mycocyclosin synthase1.14.21.90.456
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.456
5hs1VORLanosterol 14-alpha demethylase/0.456
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.455
2dhfDZFDihydrofolate reductase1.5.1.30.455
2ic3HBYGag-Pol polyprotein2.7.7.490.455
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
2y6fM9FIsopenicillin N synthase1.21.3.10.455
2z97CAMCamphor 5-monooxygenase1.14.15.10.455
2znnS44Peroxisome proliferator-activated receptor alpha/0.455
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
3nga3NGCasein kinase II subunit alpha2.7.11.10.455
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.455
3opdHIEHeat shock protein 83/0.455
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.455
4a8v2ANMajor pollen allergen Bet v 1-J/0.455
4bfpSWYTankyrase-22.4.2.300.455
4bfsZVSPantothenate kinase2.7.1.330.455
4do30LAFatty-acid amide hydrolase 13.5.1.990.455
4e960NSBromodomain-containing protein 4/0.455
4eji0QACytochrome P450 2A131.14.14.10.455
4kfj1R0Dihydrofolate reductase1.5.1.30.455
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4lfiGNPCasein kinase II subunit alpha2.7.11.10.455
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.455
5jlaNADPutative short-chain dehydrogenase/reductase/0.455
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.454
1oiyN41Cyclin-dependent kinase 22.7.11.220.454
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.454
1zq9SAMProbable dimethyladenosine transferase/0.454
2acwUPGGlycosyltransferase/0.454
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.454
2izrBRKCasein kinase I isoform gamma-32.7.11.10.454
2qbmCAMCamphor 5-monooxygenase1.14.15.10.454
2rhrEMOPutative ketoacyl reductase1.3.10.454
2x20PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic/0.454
3njoP2MAbscisic acid receptor PYR1/0.454
3pxyJWSCyclin-dependent kinase 22.7.11.220.454
4h9506UDihydrofolate reductase1.5.1.30.454
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.454
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.454
1sezOMNProtoporphyrinogen oxidase, mitochondrial1.3.3.40.453
1ungALHCyclin-dependent-like kinase 52.7.11.10.453
1uy8PU5Heat shock protein HSP 90-alpha/0.453
2cig1DGDihydrofolate reductase1.5.1.30.453
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.453
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
2znq401Peroxisome proliferator-activated receptor delta/0.453
3t3q9PLCytochrome P450 2A61.14.130.453
3t3r9PLCytochrome P450 2A61.14.130.453
4bgg844Activin receptor type-12.7.11.300.453
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.20.453
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.453
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.453
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.453
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.453
5dfcEAMBromodomain-containing protein 2/0.453
1dkfBMSRetinoic acid receptor alpha/0.452
1fkwPURAdenosine deaminase3.5.4.40.452
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.452
1nq7ARLNuclear receptor ROR-beta/0.452
2c3qGTXGlutathione S-transferase theta-12.5.1.180.452
2vf0F89Thymidylate synthase/0.452
2zb45OPProstaglandin reductase 21.3.1.480.452
3eem53VUncharacterized protein/0.452
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.452
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.452
4a6rTA8Probable aminotransferase/0.452
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4egnTWOCytochrome P450/0.452
4eiyZMAAdenosine receptor A2a/0.452
4ejgNCTCytochrome P450 2A131.14.14.10.452
4ixgIXGDihydrofolate reductase1.5.1.30.452
4kd79DRDihydrofolate reductase1.5.1.30.452
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1a59COA2-methylcitrate synthase/0.451
1dawANPCasein kinase II subunit alpha2.7.11.10.451
1dhrNADDihydropteridine reductase1.5.1.340.451
1ppjANYCytochrome b/0.451
1uy9PU6Heat shock protein HSP 90-alpha/0.451
1uyhPU0Heat shock protein HSP 90-alpha/0.451
1uymPU3Heat shock protein HSP 90-beta/0.451
1xkkFMMEpidermal growth factor receptor2.7.10.10.451
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.451
2pywADPMethylthioribose kinase2.7.1.1000.451
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.451
3br3ETHTH-type transcriptional regulator QacR/0.451
3fql79ZGenome polyprotein2.7.7.480.451
3h0a9RARetinoic acid receptor RXR-alpha/0.451
3i0rRT3Gag-Pol polyprotein2.7.7.490.451
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.451
3koo24DBifunctional epoxide hydrolase 23.3.2.100.451
3q9bB3NAcetylpolyamine amidohydrolase/0.451
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.451
3s7a684Dihydrofolate reductase1.5.1.30.451
3uyt0CKCasein kinase I isoform delta2.7.11.10.451
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.451
3vrvYSDVitamin D3 receptor/0.451
4bqg50QHeat shock protein HSP 90-alpha/0.451
4ea13RXDehydrosqualene synthase/0.451
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4ia7BIVVitamin D3 receptor A/0.451
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.451
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.451
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.451
4q73FADBifunctional protein PutA/0.451
4twpAXITyrosine-protein kinase ABL12.7.10.20.451
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.451
5iua6DXAdenosine receptor A2a/0.451
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.450
1mvsDTMDihydrofolate reductase1.5.1.30.450
1q1rFADPutidaredoxin reductase1.18.1.50.450
1rdt570Peroxisome proliferator-activated receptor gamma/0.450
1xddAAYIntegrin alpha-L/0.450
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.450
2ejvNADL-threonine 3-dehydrogenase/0.450
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.450
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.450
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.450
2om9AJAPeroxisome proliferator-activated receptor gamma/0.450
2p4yC03Peroxisome proliferator-activated receptor gamma/0.450
2w6mOA1Biotin carboxylase6.3.4.140.450
2wgjVGHHepatocyte growth factor receptor2.7.10.10.450
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.450
3kytHC2Nuclear receptor ROR-gamma/0.450
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.450
3q9zTXQCasein kinase II subunit alpha2.7.11.10.450
3qly55VUncharacterized protein/0.450
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.450
3wowANPCasein kinase II subunit alpha2.7.11.10.450
4c59FEFCyclin-G-associated kinase2.7.11.10.450
4grb0XGCasein kinase II subunit alpha2.7.11.10.450
4k2xFADPolyketide oxygenase/hydroxylase/0.450
4rupH97Vitamin D3 receptor A/0.450
4wecNADShort chain dehydrogenase/0.450
1bygSTUTyrosine-protein kinase CSK/0.449
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
1m78CLZDihydrofolate reductase1.5.1.30.449
1qzzSAMAclacinomycin 10-hydroxylase RdmB4.1.10.449
1s3uTQDDihydrofolate reductase1.5.1.30.449
1sejF89Bifunctional dihydrofolate reductase-thymidylate synthase/0.449
1tdrMTXDihydrofolate reductase1.5.1.30.449
2c3u2TPPyruvate synthase/0.449
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.449
3a4vNADNDP-sugar epimerase/0.449
3dolGWIPol protein/0.449
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.449
3l8p0CEAngiopoietin-1 receptor2.7.10.10.449
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3mnrSD1Heat shock protein HSP 90-alpha/0.449
3njoPYVAbscisic acid receptor PYR1/0.449
3s1cZIRCytokinin dehydrogenase 11.5.99.120.449
3t8xT8XT-cell surface glycoprotein CD1b/0.449
3td8D2RDihydrofolate reductase1.5.1.30.449
4aoxFADSteroid monooxygenase/0.449
4bwaN0BPyrrolysine--tRNA ligase/0.449
4deg0JJHepatocyte growth factor receptor2.7.10.10.449
4ele31IDihydrofolate reductase/0.449
4foc0UUALK tyrosine kinase receptor2.7.10.10.449
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4gk2L66Ephrin type-A receptor 32.7.10.10.449
4l2yXXKPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.449
4l4dCAMCamphor 5-monooxygenase1.14.15.10.449
4m10ICDProstaglandin G/H synthase 21.14.99.10.449
4nra2LWBromodomain adjacent to zinc finger domain protein 2B/0.449
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.449
5k2dZMAAdenosine receptor A2a/0.449
3uzcT4EAdenosine receptor A2a/0.449
3emlZMAAdenosine receptor A2a/0.449
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1db1VDXVitamin D3 receptor/0.448
1eyqNARChalcone--flavonone isomerase 15.5.1.60.448
1ig1ANPDeath-associated protein kinase 12.7.11.10.448
1y0s331Peroxisome proliferator-activated receptor delta/0.448
1zrzBI1Protein kinase C iota type2.7.11.130.448
2c27ACOMycothiol acetyltransferase2.3.1.1890.448
2cd2FOLDihydrofolate reductase1.5.1.30.448
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.448
2ea2F77Methionine aminopeptidase 2/0.448
2fzhDH1Dihydrofolate reductase1.5.1.30.448
2givACOHistone acetyltransferase KAT8/0.448
2hb8MVDVitamin D3 receptor/0.448
2ociTYCValacyclovir hydrolase3.10.448
2vwu7X1Ephrin type-B receptor 42.7.10.10.448
2w3bNDPDihydrofolate reductase1.5.1.30.448
2xikJ60Serine/threonine-protein kinase 252.7.11.10.448
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.448
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3m7rVDXVitamin D3 receptor/0.448
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.448
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.448
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3slkNDPPolyketide synthase extender module 2/0.448
3ttjJBIMitogen-activated protein kinase 102.7.11.240.448
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.448
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.448
4fk8FADFerredoxin--NADP reductase/0.448
4xldBRLPeroxisome proliferator-activated receptor gamma/0.448
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.448
5e8xSTUTGF-beta receptor type-12.7.11.300.448
1blzACVIsopenicillin N synthase1.21.3.10.447
1h1s4SPCyclin-dependent kinase 22.7.11.220.447
1iyzNDPProbable quinone oxidoreductase/0.447
1r00SAHAclacinomycin 10-hydroxylase RdmB4.1.10.447
1s0zEB1Vitamin D3 receptor/0.447
1s3yTQTDihydrofolate reductase1.5.1.30.447
1yw2PGJMitogen-activated protein kinase 14/0.447
2cy2ACOProbable acetyltransferase/0.447
2gjlFMNNitronate monooxygenase1.13.12.160.447
2vcmM11Isopenicillin N synthase1.21.3.10.447
2w3aTOPDihydrofolate reductase1.5.1.30.447
2w6qOA5Biotin carboxylase6.3.4.140.447
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.447
2zjwREFCasein kinase II subunit alpha2.7.11.10.447
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3qlsNDPDihydrofolate reductase1.5.1.30.447
3qm4PN0Cytochrome P450 2D6/0.447
3s1dZIRCytokinin dehydrogenase 11.5.99.120.447
3tscNADUncharacterized protein/0.447
3wrjCAMCamphor 5-monooxygenase1.14.15.10.447
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.447
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.447
4efuEFUHeat shock protein HSP 90-alpha/0.447
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.447
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.447
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.447
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.447
4h9814QUncharacterized protein/0.447
4jqeANPCasein kinase II subunit alpha2.7.11.10.447
4mlhVO2Glucokinase2.7.1.20.447
4nh82LCHeat shock protein HSP 90-alpha/0.447
4pnmNU1Tankyrase-22.4.2.300.447
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.447
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.447
5dt3ATPAurora kinase A2.7.11.10.447
1bim0QBRenin3.4.23.150.446
1dz6CAMCamphor 5-monooxygenase1.14.15.10.446
1e9hINRCyclin-dependent kinase 22.7.11.220.446
1fmjRTLRetinol dehydratase/0.446
1ie8KH1Vitamin D3 receptor/0.446
1qxlFR8Adenosine deaminase3.5.4.40.446
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.446
2fziDH3Dihydrofolate reductase1.5.1.30.446
2p33J07Mitogen-activated protein kinase 102.7.11.240.446
2ze2T27Gag-Pol polyprotein2.7.7.490.446
3csdEMOPutative ketoacyl reductase1.3.10.446
3dg8NDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3dogNNNCyclin-dependent kinase 22.7.11.220.446
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3k99PFTHeat shock protein HSP 90-alpha/0.446
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.446
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3upf0BUPolyprotein/0.446
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.446
4c58824Cyclin-G-associated kinase2.7.11.10.446
4cd2FOLDihydrofolate reductase1.5.1.30.446
4elb34SDihydrofolate reductase/0.446
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4fogC2FThymidylate synthase ThyA/0.446
4fv7E94Mitogen-activated protein kinase 12.7.11.240.446
4kb81QNCasein kinase I isoform delta2.7.11.10.446
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.446
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.446
4wujFMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy/0.446
4y8wSTRSteroid 21-hydroxylase/0.446
4zohFADPutative oxidoreductase FAD-binding subunit/0.446
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.446
1cm8ANPMitogen-activated protein kinase 12/0.445
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
1k6tXN1Gag-Pol polyprotein3.4.23.160.445
1pd9CO4Dihydrofolate reductase1.5.1.30.445
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.445
1t87CAMCamphor 5-monooxygenase1.14.15.10.445
1uydPU8Heat shock protein HSP 90-alpha/0.445
1uyrD1LAcetyl-CoA carboxylase/0.445
1y4lSVRBasic phospholipase A2 homolog 2/0.445
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.445
1zeoC01Peroxisome proliferator-activated receptor gamma/0.445
2c96ATPPsp operon transcriptional activator/0.445
2ci01CMLanosterol 14-alpha demethylase1.14.13.700.445
2fzjDH3Dihydrofolate reductase1.5.1.30.445
2hw2RFPRifampin ADP-ribosyl transferase/0.445
2i0ePDSProtein kinase C beta type2.7.11.130.445
2oaxSNLMineralocorticoid receptor/0.445
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.445
2qe4JJ3Estrogen receptor/0.445
2qo9ANPEphrin type-A receptor 32.7.10.10.445
2vg7NNIGag-Pol polyprotein2.7.7.490.445
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.445
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.445
3a0iAJIGlucokinase2.7.1.20.445
3c3eGDP2-phospho-L-lactate transferase/0.445
3cgdCOACoenzyme A disulfide reductase/0.445
3ddw055Glycogen phosphorylase, liver form2.4.1.10.445
3iafTPPBenzaldehyde lyase/0.445
3o8pBMUMitogen-activated protein kinase 14/0.445
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.445
3tqaNDPDihydrofolate reductase/0.445
4a9e3PFBromodomain-containing protein 2/0.445
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.445
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.445
4cp4CAMCamphor 5-monooxygenase1.14.15.10.445
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.445
4i9i1DYTankyrase-12.4.2.300.445
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.445
4oauADP2-5A-dependent ribonuclease3.1.260.445
4ocvANPAminoglycoside phosphotransferase/0.445
4xgxADPFAD:protein FMN transferase/0.445
5iubCLRAdenosine receptor A2a/0.445
1dr4HBIDihydrofolate reductase1.5.1.30.444
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1rfuADPPyridoxal kinase2.7.1.350.444
1rfvADPPyridoxal kinase2.7.1.350.444
1tduCB3Thymidylate synthase/0.444
1uy7PU4Heat shock protein HSP 90-alpha/0.444
1w1rZEACytokinin dehydrogenase 11.5.99.120.444
1w4zNAPPutative ketoacyl reductase1.3.10.444
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
2a94AP0L-lactate dehydrogenase1.1.1.270.444
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
2dsgSAHDiphthine synthase/0.444
2gjnFMNNitronate monooxygenase1.13.12.160.444
2ohvNHLGlutamate racemase/0.444
2w3wVG9Dihydrofolate reductase/0.444
2yee2ECHeat shock protein HSP 90-alpha/0.444
2ym2FADPhenylacetone monooxygenase1.14.13.920.444
3bhy7CPDeath-associated protein kinase 3/0.444
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.444
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.444
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.444
3fznD7KBenzoylformate decarboxylase4.1.1.70.444
3i8aN22Dihydrofolate reductase1.5.1.30.444
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
3oquA8SAbscisic acid receptor PYL9/0.444
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.444
3qiyQI1Botulinum neurotoxin type A3.4.24.690.444
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
3tjsD0RCytochrome P450 3A4/0.444
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.444
4awq592Heat shock protein HSP 90-alpha/0.444
4bfvZVVPantothenate kinase2.7.1.330.444
4bj9UHBTankyrase-22.4.2.300.444
4eevL1XHepatocyte growth factor receptor2.7.10.10.444
4g3rCAMCamphor 5-monooxygenase1.14.15.10.444
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.444
4g95OAGDihydrofolate reductase1.5.1.30.444
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.444
4hy6FJ1Heat shock protein HSP 90-alpha/0.444
4jr7GNPCasein kinase II subunit alpha2.7.11.10.444
4riyADPEpidermal growth factor receptor2.7.10.10.444
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.444
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.444
5av4GENDeath-associated protein kinase 12.7.11.10.444
5e8wSTUTGF-beta receptor type-12.7.11.300.444
1bucFADAcyl-CoA dehydrogenase, short-chain specific1.3.8.10.443
1c7oPPGHemolysin/0.443
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.443
1h35R01Squalene--hopene cyclase4.2.1.1290.443
1ia2TQ4Dihydrofolate reductase1.5.1.30.443
1kkq471Peroxisome proliferator-activated receptor alpha/0.443
1m2rMNYCasein kinase II subunit alpha2.7.11.10.443
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.443
1rd4L08Integrin alpha-L/0.443
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.443
1t88CAMCamphor 5-monooxygenase1.14.15.10.443
1uykPUXHeat shock protein HSP 90-alpha/0.443
1yrdCAMCamphor 5-monooxygenase1.14.15.10.443
2bakAQZMitogen-activated protein kinase 14/0.443
2dvlFADAcyl-CoA dehydrogenase/0.443
2e0nSAHPrecorrin-2 C20-methyltransferase/0.443
2ev9NAPShikimate dehydrogenase (NADP(+))/0.443
2gqwFADFerredoxin reductase/0.443
2jkkBI9Focal adhesion kinase 12.7.10.20.443
2pvnP63Casein kinase II subunit alpha2.7.11.10.443
2uxuNARHTH-type transcriptional regulator TtgR/0.443
2zawCAMCamphor 5-monooxygenase1.14.15.10.443
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.443
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.443
3eej53RUncharacterized protein/0.443
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.443
3hkoANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands/0.443
3igoANPCalmodulin-domain protein kinase 1, putative/0.443
3nmhPYVAbscisic acid receptor PYL2/0.443
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
3pj8404Cyclin-dependent kinase 22.7.11.220.443
4a9yAQZMitogen-activated protein kinase 14/0.443
4bb432WEphrin type-B receptor 42.7.10.10.443
4c57FEFCyclin-G-associated kinase2.7.11.10.443
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.443
4ead0NPThymidine phosphorylase2.4.2.40.443
4eftEFTHeat shock protein HSP 90-alpha/0.443
4g1z0VPVitamin D3 receptor A/0.443
4jq8KJ8Epidermal growth factor receptor2.7.10.10.443
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.443
4l98LRGPeroxisome proliferator-activated receptor gamma/0.443
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.443
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.443
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.443
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
4tuvCPZCytochrome P450 1191.140.443
5k2bZMAAdenosine receptor A2a/0.443
5jtbZMAAdenosine receptor A2a/0.443
4ea30NNNociceptin receptor/0.443
3sn6P0GBeta-2 adrenergic receptor/0.443
1ay0TPPTransketolase 12.2.1.10.442
1cd2FOLDihydrofolate reductase1.5.1.30.442
1dajMOTDihydrofolate reductase1.5.1.30.442
1fbyREARetinoic acid receptor RXR-alpha/0.442
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1jolFFODihydrofolate reductase1.5.1.30.442
1o5rFR9Adenosine deaminase3.5.4.40.442
1o6qR17Squalene--hopene cyclase4.2.1.1290.442
1rx7FOLDihydrofolate reductase1.5.1.30.442
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.442
1tehNADAlcohol dehydrogenase class-31.1.1.10.442
1ysx4EBSerum albumin/0.442
2a1nCAMCamphor 5-monooxygenase1.14.15.10.442
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.442
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.442
2fwyH64Heat shock protein HSP 90-alpha/0.442
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.442
2x7hPFNProstaglandin reductase 310.442
3ahiHTLProbable phosphoketolase/0.442
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.442
3cppCAMCamphor 5-monooxygenase1.14.15.10.442
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3gobHXXDdmC/0.442
3gwfFADCyclohexanone monooxygenase/0.442
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.442
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.442
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.442
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.442
3nszANPCasein kinase II subunit alpha2.7.11.10.442
3oqfS51Renin3.4.23.150.442
3oqkS52Renin3.4.23.150.442
3pe2E1BCasein kinase II subunit alpha2.7.11.10.442
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.442
3qlrQLRDihydrofolate reductase1.5.1.30.442
3sp9IL2Peroxisome proliferator-activated receptor delta/0.442
3t8vBTJM1 family aminopeptidase3.4.110.442
3uowXMPGMP synthase [glutamine-hydrolyzing]/0.442
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.442
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.442
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.442
4ez8DHFThymidylate synthase2.1.1.450.442
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.442
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4m11MXMProstaglandin G/H synthase 21.14.99.10.442
4oavACP2-5A-dependent ribonuclease3.1.260.442
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.442
4q72FADBifunctional protein PutA/0.442
5cvhADPCasein kinase II subunit alpha2.7.11.10.442
6cp4CAMCamphor 5-monooxygenase1.14.15.10.442
1drbMTXDihydrofolate reductase1.5.1.30.441
1drhNAPDihydrofolate reductase1.5.1.30.441
1f5fDHTSex hormone-binding globulin/0.441
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.441
1py5PY1TGF-beta receptor type-12.7.11.300.441
1tkaN3TTransketolase 12.2.1.10.441
1vjy460TGF-beta receptor type-12.7.11.300.441
1y4sADPChaperone protein HtpG/0.441
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.441
2fypRDEEndoplasmin/0.441
2g1pSAHDNA adenine methylase2.1.1.720.441
2gr1FADFerredoxin reductase/0.441
2rkvZBATrichothecene 3-O-acetyltransferase/0.441
2uxoTACHTH-type transcriptional regulator TtgR/0.441
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.441
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.441
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.441
3ddpRC8Cyclin-dependent kinase 22.7.11.220.441
3dds26BGlycogen phosphorylase, liver form2.4.1.10.441
3g5hYTTMycocyclosin synthase1.14.21.90.441
3ibdCPZCytochrome P450 2B61.14.130.441
3iok1P6Tyrosine-protein kinase JAK2/0.441
3jziJZLBiotin carboxylase6.3.4.140.441
3nhyA7BRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
3nnuEDBMitogen-activated protein kinase 14/0.441
3pd3A3TThreonine--tRNA ligase6.1.1.30.441
3pm1ETHTH-type transcriptional regulator QacR/0.441
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.441
3rmf20ZCyclin-dependent kinase 22.7.11.220.441
3tnwF18Cyclin-dependent kinase 22.7.11.220.441
3w0jT08Vitamin D3 receptor/0.441
3wiyLC6Induced myeloid leukemia cell differentiation protein Mcl-1/0.441
3zuxTCHTransporter/0.441
4a2jAS0Progesterone receptor/0.441
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.441
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.441
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.441
4h6rFDAProline dehydrogenase/0.441
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.441
4jbtASDCytochrome P450 monooxygenase/0.441
4ly91YYGlucokinase regulatory protein/0.441
4qzuRTLRetinol-binding protein 2/0.441
4ure1PSCyclohexanol dehydrogenase/0.441
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
5awmANPStress-activated protein kinase JNK2.7.11.240.441
5drdATPAurora kinase A2.7.11.10.441
1bk0ACVIsopenicillin N synthase1.21.3.10.440
1f28F89Thymidylate synthase2.1.1.450.440
1fmlRTLRetinol dehydratase/0.440
1ly3COGDihydrofolate reductase1.5.1.30.440
1nzfUPGDNA beta-glucosyltransferase/0.440
1u54ACPActivated CDC42 kinase 1/0.440
1v79FR7Adenosine deaminase3.5.4.40.440
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.440
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.440
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.440
2cchATPCyclin-dependent kinase 22.7.11.220.440
2iko7IGRenin3.4.23.150.440
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
2ittAEEEpidermal growth factor receptor2.7.10.10.440
2vn0TDZCytochrome P450 2C8/0.440
2ynfWHUGag-Pol polyprotein2.7.7.490.440
2zaxCAMCamphor 5-monooxygenase1.14.15.10.440
2zlcVDXVitamin D3 receptor/0.440
3bc3OPTCathepsin L13.4.22.150.440
3be9P04Casein kinase II subunit alpha2.7.11.10.440
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.440
3ed1GA3Gibberellin receptor GID1/0.440
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3fgoCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.440
3gubGUBDeath-associated protein kinase 12.7.11.10.440
3hazFADBifunctional protein PutA/0.440
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.440
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.440
3lakKR1Gag-Pol polyprotein2.7.7.490.440
3lsiFADPyranose 2-oxidase/0.440
3lu8IQXSerum albumin/0.440
3ntaCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.440
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
3qj5022Alcohol dehydrogenase class-31.1.1.10.440
3umw596Serine/threonine-protein kinase pim-12.7.11.10.440
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.440
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.440
4f7l0SOCyclin-dependent kinase 82.7.11.220.440
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.440
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.440
4h9614QDihydrofolate reductase1.5.1.30.440
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.440
4iskUMPThymidylate synthase/0.440
4iwv1J9Glucokinase2.7.1.20.440
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.440
4jq4IMNAldo-keto reductase family 1 member C2/0.440
4ktkKTKCytochrome P450/0.440
4l49CAMCamphor 5-monooxygenase1.14.15.10.440
4xivACPChemotaxis protein CheA2.7.13.30.440
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440