sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4hxr | 1A4 | Bromodomain-containing protein 4 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4hxr | 1A4 | Bromodomain-containing protein 4 | / | 1.000 | |
| 4c67 | L5S | Bromodomain-containing protein 4 | / | 0.583 | |
| 4hxn | 1A7 | Bromodomain-containing protein 4 | / | 0.576 | |
| 4hxs | 1A3 | Bromodomain-containing protein 4 | / | 0.537 | |
| 4hbw | 14Z | Bromodomain-containing protein 4 | / | 0.532 | |
| 4akn | S5B | Bromodomain-containing protein 2 | / | 0.526 | |
| 4hxm | 1A8 | Bromodomain-containing protein 4 | / | 0.522 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.512 | |
| 4alg | 1GH | Bromodomain-containing protein 2 | / | 0.511 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.511 | |
| 4nqm | Y1Z | Bromodomain-containing protein 4 | / | 0.504 | |
| 4j0r | 1H2 | Bromodomain-containing protein 4 | / | 0.501 | |
| 4lr6 | 1XA | Bromodomain-containing protein 4 | / | 0.498 | |
| 4bjx | 73B | Bromodomain-containing protein 4 | / | 0.495 | |
| 4cfk | LY2 | Bromodomain-containing protein 4 | / | 0.493 | |
| 4men | 25K | Bromodomain-containing protein 4 | / | 0.490 | |
| 4a9l | P9L | Bromodomain-containing protein 4 | / | 0.488 | |
| 4j0s | 1H3 | Bromodomain-containing protein 4 | / | 0.487 | |
| 4mr4 | 1K0 | Bromodomain-containing protein 4 | / | 0.485 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.485 | |
| 3aqa | BYH | Bromodomain-containing protein 2 | / | 0.484 | |
| 4ogi | R78 | Bromodomain-containing protein 4 | / | 0.481 | |
| 4a9n | A9N | Bromodomain-containing protein 2 | / | 0.479 | |
| 4c66 | H4C | Bromodomain-containing protein 4 | / | 0.479 | |
| 5bt5 | 2LO | Bromodomain-containing protein 2 | / | 0.479 | |
| 4mep | 24Y | Bromodomain-containing protein 4 | / | 0.478 | |
| 4nr8 | 2LL | Bromodomain-containing protein 4 | / | 0.477 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 4gpj | 0Q1 | Bromodomain-containing protein 4 | / | 0.472 | |
| 4bw2 | UTH | Bromodomain-containing protein 4 | / | 0.469 | |
| 4bw3 | 9BM | Bromodomain-containing protein 4 | / | 0.469 | |
| 4hby | 13F | Bromodomain-containing protein 4 | / | 0.469 | |
| 4a9o | A9O | Bromodomain-containing protein 2 | / | 0.461 | |
| 2yel | WSH | Bromodomain-containing protein 4 | / | 0.460 | |
| 4qzs | JQ1 | Bromodomain-containing protein 4 | / | 0.459 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.458 | |
| 3zyu | 1GH | Bromodomain-containing protein 4 | / | 0.456 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.449 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.449 | |
| 4bw1 | S5B | Bromodomain-containing protein 4 | / | 0.448 | |
| 4j1p | 1K0 | Bromodomain-containing protein 2 | / | 0.448 | |
| 4meq | 25O | Bromodomain-containing protein 4 | / | 0.447 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4flp | JQ1 | Bromodomain testis-specific protein | / | 0.444 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2yem | WSH | Bromodomain-containing protein 4 | / | 0.442 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 |