Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 1.000 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.586 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.574 | |
| 4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.545 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.541 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.529 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.527 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.524 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.520 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.518 | |
| 3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.517 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.513 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.512 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.510 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.508 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.508 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.507 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.507 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.502 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.502 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.501 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.497 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.496 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.495 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.495 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.494 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.494 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.493 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.492 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.492 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.490 | |
| 1pme | SB2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.489 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.489 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.489 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.486 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.485 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.485 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.484 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.484 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.484 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.483 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.482 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.482 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.482 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.481 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.481 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 1p4f | DRG | Death-associated protein kinase 1 | 2.7.11.1 | 0.480 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.480 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.479 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.479 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.479 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.479 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.478 | |
| 4g16 | 0VM | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.478 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.478 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.478 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.477 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.476 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.476 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.475 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.475 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.475 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.475 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.474 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.474 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.474 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.473 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.473 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.473 | |
| 4hgt | 15G | Casein kinase I isoform delta | 2.7.11.1 | 0.473 | |
| 5dmz | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.473 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.472 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.471 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.471 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.471 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.471 | |
| 4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.471 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.471 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.470 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.470 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.470 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.470 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.470 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.469 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.469 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.469 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.469 | |
| 2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.468 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.468 | |
| 4ux9 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.468 | |
| 5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.468 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 4bi1 | ZO6 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.467 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.467 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.466 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.466 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.466 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.466 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.466 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.465 | |
| 3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.465 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.464 | |
| 4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.463 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.463 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.463 | |
| 4fx3 | 60K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.462 | |
| 2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.462 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.461 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.460 | |
| 4c4h | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.460 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.459 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.459 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4fv0 | EK3 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.459 | |
| 4kbc | 1QJ | Casein kinase I isoform delta | 2.7.11.1 | 0.459 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.459 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.459 | |
| 1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.458 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.458 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.458 | |
| 3q92 | XNB | Ketohexokinase | / | 0.458 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.458 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.458 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.457 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.457 | |
| 3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.457 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.457 | |
| 3umw | 596 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.457 | |
| 1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.456 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.456 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.456 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.456 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4ih8 | B43 | Calmodulin-domain protein kinase 1 | / | 0.456 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.456 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.456 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 3umx | Q18 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 3vqu | O22 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.455 | |
| 3wi6 | YRZ | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.455 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.455 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.455 | |
| 4xhg | ADP | Uncharacterized protein | / | 0.455 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.454 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.454 | |
| 3kn5 | ANP | Ribosomal protein S6 kinase alpha-5 | 2.7.11.1 | 0.454 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 4an9 | 2P7 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.454 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.454 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.454 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3qa2 | XNA | Ketohexokinase | / | 0.453 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 4c4f | 7CE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.453 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.452 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.452 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.451 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
| 2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.451 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 4bdg | P3J | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.451 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.450 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.450 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.450 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.450 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.449 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.449 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.449 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.448 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.448 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3fmj | FMJ | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3lij | ANP | Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands | / | 0.448 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.448 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.447 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.447 | |
| 2chl | DKI | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.447 | |
| 2vww | 7X2 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.447 | |
| 3fi3 | JK2 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.447 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.447 | |
| 4a1z | ADP | Kinesin-like protein KIF11 | / | 0.447 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.447 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.447 | |
| 4cfn | JYM | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4ftj | H8K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.447 | |
| 1ke7 | LS3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1tvo | FRZ | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.446 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.446 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.446 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.445 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.445 | |
| 3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.445 | |
| 3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3nlb | 5BE | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 4zca | ADP | Kinesin-like protein KIF11 | / | 0.445 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2c47 | 5ID | Casein kinase I isoform gamma-2 | / | 0.444 | |
| 2euf | LQQ | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.444 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 2pz5 | ACP | Fibroblast growth factor receptor 2 | / | 0.444 | |
| 2wqe | ADP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.444 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 3ork | AGS | Serine/threonine protein kinase | / | 0.444 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.444 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.444 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.443 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 3ddq | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.442 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.442 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.442 | |
| 1zao | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.442 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.442 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3gu6 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3qai | XNN | Ketohexokinase | / | 0.442 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 4btk | DTQ | Tau-tubulin kinase 1 | 2.7.11.1 | 0.442 | |
| 4i41 | MIX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.442 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.442 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.441 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.441 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.441 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.441 | |
| 4foc | 0UU | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4ft3 | H1K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4ft9 | H4K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4g6o | E28 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.441 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 5ap5 | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.441 | |
| 5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 1c70 | L75 | Protease | / | 0.440 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.440 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.440 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 2vgo | AD5 | Aurora kinase B-A | 2.7.11.1 | 0.440 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.440 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.440 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.440 | |
| 4eon | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.440 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4ogr | ADN | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.440 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.440 |