sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4hej | 14D | Thymidylate kinase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4hej | 14D | Thymidylate kinase | / | 1.000 | |
| 4gsy | 0Y5 | Thymidylate kinase | / | 0.656 | |
| 4hld | 16T | Thymidylate kinase | / | 0.554 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.478 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.452 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.452 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.451 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.449 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 2ejz | SAH | Diphthine synthase | / | 0.447 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.444 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 5ero | 210 | Fusicoccadiene synthase | 2.5.1.29 | 0.441 |