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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4h4c10D4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4h4c10D4-hydroxy-3-methylbut-2-enyl diphosphate reductase/1.000
3kemIPE4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.724
3ke8EIP4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.669
4h4e10G4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.633
4eb30O34-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.623
3utd0CJ4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.619
4h4d10E4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.605
3zgl10E4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.583
3zgn10G4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.541
2g1n1IGRenin3.4.23.150.507
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.505
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.502
1drhNAPDihydrofolate reductase1.5.1.30.501
3ed1GA3Gibberellin receptor GID1/0.498
4m6jNDPDihydrofolate reductase1.5.1.30.498
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.497
2bxmIMNSerum albumin/0.495
1kvkATPMevalonate kinase2.7.1.360.494
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.493
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.493
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.492
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.491
2zbaZBATrichothecene 3-O-acetyltransferase/0.490
4a8v2ANMajor pollen allergen Bet v 1-J/0.490
2qbmCAMCamphor 5-monooxygenase1.14.15.10.489
3fp0FP015-O-acetyltransferase/0.489
4gk3L87Ephrin type-A receptor 32.7.10.10.489
1nooCAHCamphor 5-monooxygenase1.14.15.10.487
3rbqGLY_ALA_GLY_DAOProtein unc-119 homolog A/0.487
3zewSTUEphrin type-B receptor 42.7.10.10.486
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.486
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.485
2a94AP0L-lactate dehydrogenase1.1.1.270.485
2j2pSC2Ficolin-2/0.485
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.485
2rkvZBATrichothecene 3-O-acetyltransferase/0.484
4okx198Androgen receptor/0.484
2os1BB2Peptide deformylase/0.483
4r1lADPPhenylacetate-coenzyme A ligase/0.483
1rx1NAPDihydrofolate reductase1.5.1.30.482
2c29NAPDihydroflavonol 4-reductase/0.482
2wgeTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.482
4b1rITCTetracycline repressor protein class D/0.482
2bxqIMNSerum albumin/0.481
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.481
4jqlVJ6Heat shock protein HSP 90-alpha/0.481
1gpeFADGlucose oxidase1.1.3.40.480
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.480
2givACOHistone acetyltransferase KAT8/0.480
1cs4FOKAdenylate cyclase type 2/0.479
1cs4FOKAdenylate cyclase type 5/0.479
1f20NAPNitric oxide synthase, brain1.14.13.390.479
1p0hACOMycothiol acetyltransferase2.3.1.1890.479
1vbiNADMalate/L-lactate dehydrogenase family protein/0.479
2p8hMY9Beta-secretase 13.4.23.460.479
3oqfS51Renin3.4.23.150.479
1zrzBI1Protein kinase C iota type2.7.11.130.478
2a1oCAMCamphor 5-monooxygenase1.14.15.10.478
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.478
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.478
2he5NDPAldo-keto reductase family 1 member C211.1.10.477
2iyfERYOleandomycin glycosyltransferase2.4.10.477
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.477
3phiNDPShikimate dehydrogenase (NADP(+))/0.477
3wbfNAPMeso-diaminopimelate D-dehydrogenase/0.477
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.477
4l4dCAMCamphor 5-monooxygenase1.14.15.10.477
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.477
1ezvUQ6Cytochrome b/0.476
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.476
3fhxPLPPyridoxal kinase2.7.1.350.476
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.476
3a7rLAQLipoate-protein ligase A6.3.1.200.475
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.475
1h74ADPHomoserine kinase2.7.1.390.474
1tqf32PBeta-secretase 13.4.23.460.474
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.474
3lqfNADGalactitol dehydrogenase/0.474
1ay0TPPTransketolase 12.2.1.10.473
1mvsDTMDihydrofolate reductase1.5.1.30.473
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
1rpnNDPGDP-mannose 4,6-dehydratase/0.473
2yx6ADPUncharacterized protein/0.473
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.473
4a862ANMajor pollen allergen Bet v 1-A/0.473
2a9y26AAdenosine kinase2.7.1.200.472
2gvdFKPAdenylate cyclase type 2/0.472
2gvdFKPAdenylate cyclase type 5/0.472
2znpK55Peroxisome proliferator-activated receptor delta/0.472
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.472
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.472
1eyqNARChalcone--flavonone isomerase 15.5.1.60.471
1u71MXADihydrofolate reductase1.5.1.30.471
1wzeNADMalate dehydrogenase/0.471
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.471
2hr8SAHDiphthine synthase/0.471
2pg0FADAcyl-CoA dehydrogenase/0.471
2z4sADPChromosomal replication initiator protein DnaA/0.471
3cppCAMCamphor 5-monooxygenase1.14.15.10.471
3d2mCOAAmino-acid acetyltransferase/0.471
3ekrPY9Heat shock protein HSP 90-alpha/0.471
4emtC2EStimulator of interferon genes protein/0.471
4k28NADShikimate dehydrogenase family protein/0.471
1cjtFOKAdenylate cyclase type 2/0.470
1cjtFOKAdenylate cyclase type 5/0.470
1culFOKAdenylate cyclase type 2/0.470
1culFOKAdenylate cyclase type 5/0.470
1opbRETRetinol-binding protein 2/0.470
1tl7FOKAdenylate cyclase type 2/0.470
1tl7FOKAdenylate cyclase type 5/0.470
2b53D23Cyclin-dependent kinase 22.7.11.220.470
2gjlFMNNitronate monooxygenase1.13.12.160.470
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.470
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.470
4i1iNADMalate dehydrogenase/0.470
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.470
5kf1ACOPredicted acetyltransferase/0.470
1ia1NDPDihydrofolate reductase1.5.1.30.469
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.469
2qn3F55Glycogen phosphorylase, muscle form2.4.1.10.469
2x7hPFNProstaglandin reductase 310.469
2zshGA3Gibberellin receptor GID1A30.469
3a0tADPSensor histidine kinase/0.469
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3hk1B64Fatty acid-binding protein, adipocyte/0.469
3qlrNDPDihydrofolate reductase1.5.1.30.469
4i8vBHFCytochrome P450 1A11.14.14.10.469
4x3lMTARNA 2'-O ribose methyltransferase/0.469
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.469
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.468
1xe55FEPlasmepsin-23.4.23.390.468
2vprTDCTetracycline repressor protein class H/0.468
3ajrNADNDP-sugar epimerase/0.468
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.468
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
3otwCOAPhosphopantetheine adenylyltransferase/0.468
3qftFADNADPH--cytochrome P450 reductase/0.468
4c04SFGProtein arginine N-methyltransferase 6/0.468
4y1bNAPAntE/0.468
1b2lNDCAlcohol dehydrogenase1.1.1.10.467
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.467
1g28FMNPHY3/0.467
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.467
1pd9CO4Dihydrofolate reductase1.5.1.30.467
1rx8NAPDihydrofolate reductase1.5.1.30.467
1wxjIPLTryptophan synthase alpha chain/0.467
3orfNADDihydropteridine reductase1.5.1.340.467
3qvpFADGlucose oxidase1.1.3.40.467
4oztP1AEcdysone receptor, putative/0.467
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.467
1mvtDTMDihydrofolate reductase1.5.1.30.466
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.466
2cv1ATPGlutamate--tRNA ligase6.1.1.170.466
2gtnLIEMitogen-activated protein kinase 14/0.466
2uxuNARHTH-type transcriptional regulator TtgR/0.466
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.466
2yjzNAPMetalloreductase STEAP41.16.10.466
3i25MV7Beta-secretase 13.4.23.460.466
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.466
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.466
4l4eCAMCamphor 5-monooxygenase1.14.15.10.466
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.465
1o76CAMCamphor 5-monooxygenase1.14.15.10.465
1t2bCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.465
2ea2F77Methionine aminopeptidase 2/0.465
2rqfJH3Hemolymph juvenile hormone binding protein/0.465
2vkmBSDBeta-secretase 13.4.23.460.465
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
3fwiCAMCamphor 5-monooxygenase1.14.15.10.465
3gwdFADCyclohexanone monooxygenase/0.465
3h06VBPGlutamate receptor 2/0.465
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.465
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.465
4df2FMNNADPH dehydrogenase/0.465
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.465
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.465
1d2sDHTSex hormone-binding globulin/0.464
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.464
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.464
3eblGA4Gibberellin receptor GID1/0.464
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.464
3rqqBA3ADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.464
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.464
4dbzNDPPutative ketoacyl reductase1.3.10.464
4kqgDMDNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.464
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.463
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.463
1owlFADDeoxyribodipyrimidine photo-lyase4.1.99.30.463
2e95B75Geranylgeranyl pyrophosphate synthase/0.463
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.463
3ekuCY9Actin-5C/0.463
4cjfRVNIntegrase/0.463
4dptAGSMevalonate diphosphate decarboxylase/0.463
4l4xNDPAmphI/0.463
4twnB96Ephrin type-A receptor 32.7.10.10.463
1dr3HBIDihydrofolate reductase1.5.1.30.462
2e0nSAHPrecorrin-2 C20-methyltransferase/0.462
2e8qSAHDiphthine synthase/0.462
2gyuHI6Acetylcholinesterase3.1.1.70.462
2v16C47Renin3.4.23.150.462
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3lsiFADPyranose 2-oxidase/0.462
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.462
4b0cC9H3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase4.2.1.590.462
4rww2BALmo2692 protein/0.462
4tuvCPZCytochrome P450 1191.140.462
5a3bAPRSIR2 family protein/0.462
5cyoGDPSeptin-9/0.462
1t2cNAIL-lactate dehydrogenase1.1.1.270.461
1tysTMPThymidylate synthase/0.461
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.461
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.461
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.461
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
3toxNAPPutative oxidoreductase/0.461
4co4ATPNitrogen regulatory protein P-II 1/0.461
4ead0NPThymidine phosphorylase2.4.2.40.461
4em4FADCoenzyme A disulfide reductase/0.461
4z875GPInosine-5'-monophosphate dehydrogenase/0.461
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.461
1dr2TAPDihydrofolate reductase1.5.1.30.460
1dz8CAMCamphor 5-monooxygenase1.14.15.10.460
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.460
1snyNAPLD36273p/0.460
2c20NADUDP-glucose 4-epimerase/0.460
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.460
2j7pGNPSignal recognition particle protein/0.460
2j7pGNPSignal recognition particle receptor FtsY/0.460
2npnSAMPutative cobalamin synthesis related protein/0.460
3b9lAZZSerum albumin/0.460
3c35KAIGlutamate receptor ionotropic, kainate 1/0.460
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.460
3nmpPYVAbscisic acid receptor PYL2/0.460
4c717RD3-oxoacyl-ACP synthase/0.460
4l4fCAMCamphor 5-monooxygenase1.14.15.10.460
4pleCPSNuclear receptor subfamily 5 group A member 2/0.460
4qysPLRTryptophan synthase beta chain 24.2.1.200.460
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.460
5cb3APRO-acetyl-ADP-ribose deacetylase/0.460
1flmFMNFMN-binding protein/0.459
1h63FMNPentaerythritol tetranitrate reductase/0.459
1h65GDPTranslocase of chloroplast 343.6.50.459
1h73ANPHomoserine kinase2.7.1.390.459
1i59ANPChemotaxis protein CheA2.7.13.30.459
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
2d5nNDPRiboflavin biosynthesis protein RibD1.1.1.1930.459
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.459
2g8yNADHydroxycarboxylate dehydrogenase B/0.459
2q9cGNPSignal recognition particle receptor FtsY/0.459
2w9hTOPDihydrofolate reductase1.5.1.30.459
2y6o1N1Ephrin type-A receptor 42.7.10.10.459
3b2sB2STrichothecene 3-O-acetyltransferase/0.459
3e92G6AMitogen-activated protein kinase 14/0.459
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.459
3phjDHKShikimate dehydrogenase (NADP(+))/0.459
3u8k09PAcetylcholine-binding protein/0.459
3zkyWT4Isopenicillin N synthase1.21.3.10.459
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.459
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.459
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.459
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.458
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.458
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.458
2v3wTPPBenzoylformate decarboxylase4.1.1.70.458
2w6zL21Biotin carboxylase6.3.4.140.458
3amfFMNFMN-binding protein/0.458
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.458
3h3sH15Collagen type IV alpha-3-binding protein/0.458
3owj1ELCasein kinase II subunit alpha2.7.11.10.458
3ppoDCKGlycine betaine/carnitine/choline-binding protein OpuCC/0.458
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
4c9pCAMCytochrome P450/0.458
4epq0RRPoly(ADP-ribose) glycohydrolase/0.458
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.458
4jc51K5Stimulator of interferon genes protein/0.458
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.458
1gvv0GMEndothiapepsin3.4.23.220.457
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.457
2c27ACOMycothiol acetyltransferase2.3.1.1890.457
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.457
2ed5SAHDiphthine synthase/0.457
2eldSAHDiphthine synthase/0.457
2huxSAHDiphthine synthase/0.457
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.457
2wxvWXVCyclin-dependent kinase 22.7.11.220.457
2xvv9DNSerum albumin/0.457
2ym1FADPhenylacetone monooxygenase1.14.13.920.457
3a9wNADNDP-sugar epimerase/0.457
3exnACOProbable acetyltransferase/0.457
3ixp834Ecdysone receptor/0.457
3kc02T5Fructose-1,6-bisphosphatase 13.1.3.110.457
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.457
3rfxNADUronate dehydrogenase/0.457
3t3q9PLCytochrome P450 2A61.14.130.457
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.457
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.457
4c72TLG3-oxoacyl-ACP synthase/0.457
4l4aCAMCamphor 5-monooxygenase1.14.15.10.457
4nm9FADBifunctional protein PutA/0.457
4u7wNDPMxaA/0.457
1dhrNADDihydropteridine reductase1.5.1.340.456
1p84UQ6Cytochrome b/0.456
1toiHCIAspartate aminotransferase2.6.1.10.456
1u0hFOKAdenylate cyclase type 2/0.456
1u0hFOKAdenylate cyclase type 5/0.456
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.456
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.456
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.456
2nnqT4BFatty acid-binding protein, adipocyte/0.456
2ogyC2F5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase2.1.1.2580.456
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.456
3h3r14HCollagen type IV alpha-3-binding protein/0.456
3imgBZ3Pantothenate synthetase6.3.2.10.456
3mdmFJZCholesterol 24-hydroxylase/0.456
3nj0PYVAbscisic acid receptor PYL2/0.456
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.456
4an4DUDPutative glycosyl transferase/0.456
4j7xNAPSepiapterin reductase1.1.1.1530.456
4rx6ATPNitrogen regulatory PII-like protein/0.456
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.456
1cjuFOKAdenylate cyclase type 2/0.455
1cjuFOKAdenylate cyclase type 5/0.455
1dr5NAPDihydrofolate reductase1.5.1.30.455
1ek2CDUBifunctional epoxide hydrolase 2/0.455
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.455
1np7FADCryptochrome DASH/0.455
1ppjANYCytochrome b/0.455
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.455
1ykdCMPAdenylate cyclase/0.455
1yrcCAMCamphor 5-monooxygenase1.14.15.10.455
2fj1CTCTetracycline repressor protein class D/0.455
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.455
2rc4ACOHistone acetyltransferase KAT6A/0.455
2zsiGA4Gibberellin receptor GID1A30.455
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.455
3drcMTXDihydrofolate reductase1.5.1.30.455
3f03FMNPentaerythritol tetranitrate reductase/0.455
3fr28CAFatty acid-binding protein, adipocyte/0.455
3n4kSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.455
3qvrFADGlucose oxidase1.1.3.40.455
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.455
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.455
4hxyNDPPlm1/0.455
4ii4BYC1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.455
4irnFADAnaB/0.455
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.455
4wqmFADToluene-4-monooxygenase electron transfer component1.18.1.30.455
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.455
5iu4ZMAAdenosine receptor A2a/0.455
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.454
1o2g696Prothrombin3.4.21.50.454
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.454
2nu9COASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.454
2qo9ANPEphrin type-A receptor 32.7.10.10.454
2rlcCHDCholoylglycine hydrolase3.5.1.240.454
2yy8SAMtRNA (cytidine(56)-2'-O)-methyltransferase/0.454
3h2sNDPPutative NADH-flavin reductase/0.454
3h4vDVPPteridine reductase 11.5.1.330.454
3ih0ANPUncharacterized sugar kinase PH14592.7.10.454
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.454
4dpy2P0Mevalonate diphosphate decarboxylase/0.454
4g95OAGDihydrofolate reductase1.5.1.30.454
4gn8ASORegucalcin3.1.1.170.454
4jhz1KVBeta-glucuronidase3.2.1.310.454
4kh0ATPAspartate carbamoyltransferase regulatory chain {ECO:0000256|HAMAP-Rule:MF_00002}/0.454
4kin1M8Mitogen-activated protein kinase 14/0.454
4ku2MYA3-oxoacyl-[ACP] synthase III/0.454
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.454
4r81FMNPredicted NADH dehydrogenase/0.454
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.454
4uocNCNCinA-like protein/0.454
4xq9NADHomospermidine synthase2.5.1.440.454
4xz3COAAcyl-CoA synthetase (NDP forming)/0.454
4z9rFMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.454
1aiqCB3Thymidylate synthase/0.453
1icqFMN12-oxophytodienoate reductase 11.3.1.420.453
1m78NDPDihydrofolate reductase1.5.1.30.453
1mg5NAIAlcohol dehydrogenase1.1.1.10.453
1mjaCOAHistone acetyltransferase ESA1/0.453
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.453
1o6zNADMalate dehydrogenase/0.453
1phePIYCamphor 5-monooxygenase1.14.15.10.453
1rx8FOLDihydrofolate reductase1.5.1.30.453
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.453
2bt4CA23-dehydroquinate dehydratase4.2.1.100.453
2ek2SAHDiphthine synthase/0.453
2emrSAHDiphthine synthase/0.453
2nniMTKCytochrome P450 2C8/0.453
2pb4SAHDiphthine synthase/0.453
2q46NAPUncharacterized protein At5g02240/0.453
2v13C40Renin3.4.23.150.453
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.453
3aosJH2Hemolymph juvenile hormone binding protein/0.453
3isjA8DPantothenate synthetase6.3.2.10.453
3maaFKPAdenylate cyclase type 2/0.453
3maaFKPAdenylate cyclase type 5/0.453
3rqhB6PADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.453
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.453
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.453
4olfHFGProline--tRNA ligase6.1.1.150.453
4u0mATPCyclic GMP-AMP synthase/0.453
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.453
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.453
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.452
1itzTPPTransketolase, chloroplastic2.2.1.10.452
1mj9COAHistone acetyltransferase ESA1/0.452
1mjbACOHistone acetyltransferase ESA1/0.452
1n83CLRNuclear receptor ROR-alpha/0.452
1towCRZFatty acid-binding protein, adipocyte/0.452
1w51L01Beta-secretase 13.4.23.460.452
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.452
2dxvSAHDiphthine synthase/0.452
2eleSAHDiphthine synthase/0.452
2gjnFMNNitronate monooxygenase1.13.12.160.452
2h94FADLysine-specific histone demethylase 1A10.452
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.452
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.452
2y3pSM8DNA gyrase subunit A/0.452
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.452
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.452
3f4bTCLEnoyl-acyl carrier protein reductase/0.452
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.452
4dpuAGSMevalonate diphosphate decarboxylase/0.452
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.452
4yfy1YJVioF/0.452
1dyiFOLDihydrofolate reductase1.5.1.30.451
1h50FMNPentaerythritol tetranitrate reductase/0.451
1hb1OCVIsopenicillin N synthase1.21.3.10.451
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1pjcNADAlanine dehydrogenase/0.451
1pqc444Oxysterols receptor LXR-beta/0.451
1qorNDPQuinone oxidoreductase 1/0.451
1rw8580TGF-beta receptor type-12.7.11.300.451
1yw8A75Methionine aminopeptidase 2/0.451
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.451
2bkzSBCCyclin-dependent kinase 22.7.11.220.451
2fznFADBifunctional protein PutA1.5.5.20.451
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.451
2qboCAMCamphor 5-monooxygenase1.14.15.10.451
2qfoA51Heat shock protein HSP 90-alpha/0.451
2rcyNAPPyrroline-5-carboxylate reductase/0.451
2x90EALAngiotensin-converting enzyme3.4.15.10.451
2znq401Peroxisome proliferator-activated receptor delta/0.451
3h3t16HCollagen type IV alpha-3-binding protein/0.451
3iifAPRCore histone macro-H2A.1/0.451
3junAJDPhenazine biosynthesis protein A/B/0.451
3l63CAMCamphor 5-monooxygenase1.14.15.10.451
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.451
3oibFDAPutative acyl-CoA dehydrogenase/0.451
3pl8FADPyranose 2-oxidase/0.451
3raiX85Cyclin-dependent kinase 22.7.11.220.451
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.451
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4c02TAKActivin receptor type-12.7.11.300.451
4enhFVXCholesterol 24-hydroxylase/0.451
4jzr4JREgl nine homolog 1/0.451
4mv4ACPBiotin carboxylase6.3.4.140.451
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.451
4qknJMSAlpha-ketoglutarate-dependent dioxygenase FTO/0.451
3sn6P0GBeta-2 adrenergic receptor/0.451
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.450
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1n3sGTPGTP cyclohydrolase 13.5.4.160.450
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.450
1txtCAAHMG-CoA synthase/0.450
1v35NAIEnoyl-ACP reductase/0.450
1z1fSTLResveratrol synthase/0.450
1zemNADXylitol dehydrogenase/0.450
2cftPLPPyridoxal phosphate phosphatase/0.450
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
2vukP83Cellular tumor antigen p53/0.450
2vzzSCAPutative succinyl-CoA transferase Rv0802c2.8.30.450
2xviFADPutative flavin-containing monooxygenase/0.450
2ylzFADPhenylacetone monooxygenase1.14.13.920.450
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.450
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.450
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3e8xNAPBH1520 protein/0.450
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.450
3mvm39PMitogen-activated protein kinase 14/0.450
3nr4PYVAbscisic acid receptor PYL2/0.450
3ns2PYVAbscisic acid receptor PYL2/0.450
3upf0BUPolyprotein/0.450
3w8eNAD3-hydroxybutyrate dehydrogenase/0.450
3wrhCAMCamphor 5-monooxygenase1.14.15.10.450
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.450
4nbwNADShort-chain dehydrogenase/reductase SDR/0.450
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.450
5idwNAPShort-chain dehydrogenase/reductase SDR/0.450
4xnw2IDP2Y purinoceptor 1/0.450
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.449
1kfbIGPTryptophan synthase alpha chain/0.449
2ag1TPPBenzaldehyde lyase/0.449
2ed3SAHDiphthine synthase/0.449
2fhnBNIAvidin-related protein 4/5/0.449
2ii4COALipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial2.3.1.1680.449
2ij7TPFMycocyclosin synthase1.14.21.90.449
2p83MR0Beta-secretase 13.4.23.460.449
2v5aLZLBiotin carboxylase6.3.4.140.449
2wu4HBPAcetylcholinesterase3.1.1.70.449
2zvcSAHPrecorrin-3 C17-methyltransferase/0.449
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.449
3pqfNADL-lactate dehydrogenase1.1.1.270.449
3q1fYPPBeta-lactamase/0.449
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.449
3rdqDTBStreptavidin/0.449
3s55NADPutative short-chain dehydrogenase/reductase/0.449
3w8fNAD3-hydroxybutyrate dehydrogenase/0.449
4dneDTBStreptavidin/0.449
4eqrCOACoenzyme A disulfide reductase/0.449
4x5hFOLDihydrofolate reductase1.5.1.30.449
4z87GDPInosine-5'-monophosphate dehydrogenase/0.449
1bmdNADMalate dehydrogenase/0.448
1ipeNDPTropinone reductase 21.1.1.2360.448
1l5k1RBNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.448
1p5rCOAFormyl-CoA:oxalate CoA-transferase/0.448
1t88CAMCamphor 5-monooxygenase1.14.15.10.448
1wziNDPMalate dehydrogenase/0.448
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.448
1z7yAA5Cysteine synthase 12.5.1.470.448
2a1mCAMCamphor 5-monooxygenase1.14.15.10.448
2dsgSAHDiphthine synthase/0.448
2e4nSAHDiphthine synthase/0.448
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.448
2fieA74Fructose-1,6-bisphosphatase 13.1.3.110.448
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.448
2vhvNAIAlanine dehydrogenase1.4.1.10.448
3d4pNADL-lactate dehydrogenase 11.1.1.270.448
3ibqATPPyridoxal kinase/0.448
3ivcFG4Pantothenate synthetase6.3.2.10.448
4bfvZVVPantothenate kinase2.7.1.330.448
4du82P0Mevalonate diphosphate decarboxylase/0.448
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.448
4qnaX11Serine/threonine-protein kinase 242.7.11.10.448
4xboSAHtRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ2.1.1.2000.448
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.448
1f8fNADBenzyl alcohol dehydrogenase/0.447
1gaqFADFerredoxin/0.447
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.447
1l4hNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.447
1phhFADp-hydroxybenzoate hydroxylase/0.447
1q19SSCCarbapenam-3-carboxylate synthase6.3.3.60.447
1w6hTITPlasmepsin-23.4.23.390.447
1wngSAHDiphthine synthase/0.447
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.447
2ab8MTPAdenosine kinase2.7.1.200.447
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.447
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2dhfDZFDihydrofolate reductase1.5.1.30.447
2dv7SAHDiphthine synthase/0.447
2el0SAHDiphthine synthase/0.447
2gblATPCircadian clock protein kinase KaiC2.7.11.10.447
2ibzUQ6Cytochrome b/0.447
2pckSAHDiphthine synthase/0.447
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.447
2qpyDHTAndrogen receptor/0.447
2rehFADNitroalkane oxidase1.7.3.10.447
2vbdV10Isopenicillin N synthase1.21.3.10.447
2vieVG0Beta-secretase 13.4.23.460.447
2xuhTZ4Acetylcholinesterase3.1.1.70.447
2zevIPEGeranylgeranyl pyrophosphate synthase/0.447
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.447
3c14FOKAdenylate cyclase type 2/0.447
3c14FOKAdenylate cyclase type 5/0.447
3cib314Beta-secretase 13.4.23.460.447
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.447
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.447
3rdiCMPcAMP-activated global transcriptional regulator CRP/0.447
3s1dZIRCytokinin dehydrogenase 11.5.99.120.447
3tbaADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.447
3tjzGNPADP-ribosylation factor 1/0.447
3zsxN44Integrase/0.447
4afgQMRAchbp/0.447
4bfwZVWPantothenate kinase2.7.1.330.447
4deg0JJHepatocyte growth factor receptor2.7.10.10.447
4e8yIHAD-beta-D-heptose 7-phosphate kinase/0.447
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.447
4gurFADLysine-specific histone demethylase 1B10.447
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.447
4l8u9AZSerum albumin/0.447
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.447
4pb25UDNucleoside permease/0.447
4prvADPDNA gyrase subunit B/0.447
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.447
1a8rGTPGTP cyclohydrolase 13.5.4.160.446
1bil0IURenin3.4.23.150.446
1c5nESIProthrombin3.4.21.50.446
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.446
1pdhFASp-hydroxybenzoate hydroxylase/0.446
1pxxDIFProstaglandin G/H synthase 21.14.99.10.446
1txiTX5Vitamin D3 receptor/0.446
1ualSAHtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.446
1y9dTPPPyruvate oxidase1.2.3.30.446
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.446
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.446
2emuSAHDiphthine synthase/0.446
2gcqDOIAdenylosuccinate synthetase/0.446
2ghlLIBMitogen-activated protein kinase 14/0.446
2itpAEEEpidermal growth factor receptor2.7.10.10.446
2uywBTNAvd protein/0.446
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.446
3a4vNADNDP-sugar epimerase/0.446
3c15FOKAdenylate cyclase type 2/0.446
3c15FOKAdenylate cyclase type 5/0.446
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3fwjCAMCamphor 5-monooxygenase1.14.15.10.446
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.446
3lqsPSZD-alanine aminotransferase2.6.1.210.446
3pldF90Endothiapepsin3.4.23.220.446
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.446
3t6iNC9Endothiapepsin3.4.23.220.446
3vjoANPEpidermal growth factor receptor2.7.10.10.446
3vucHHERenin3.4.23.150.446
4bfzZVZPantothenate kinase2.7.1.330.446
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.446
4gg70J8Hepatocyte growth factor receptor2.7.10.10.446
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.446
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.446
4j7uNAPSepiapterin reductase1.1.1.1530.446
4jlk1NODeoxycytidine kinase2.7.1.740.446
4k6fNAPPutative Acetoacetyl-CoA reductase/0.446
4kgkGTPUncharacterized protein/0.446
4lol1YEStimulator of interferon genes protein/0.446
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.446
4okb198Androgen receptor/0.446
4uyg73BBromodomain-containing protein 2/0.446
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.446
1bk0ACVIsopenicillin N synthase1.21.3.10.445
1dr3TAPDihydrofolate reductase1.5.1.30.445
1e800GQEndothiapepsin3.4.23.220.445
1f20FADNitric oxide synthase, brain1.14.13.390.445
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.445
1jolFFODihydrofolate reductase1.5.1.30.445
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.445
1rzuADPGlycogen synthase 12.4.1.210.445
1stpBTNStreptavidin/0.445
1v453DGPurine nucleoside phosphorylase2.4.2.10.445
1x1cSAHC-20 methyltransferase/0.445
2ehlSAHDiphthine synthase/0.445
2ek7SAHDiphthine synthase/0.445
2fypRDEEndoplasmin/0.445
2g78REACellular retinoic acid-binding protein 2/0.445
2gv8NDPThiol-specific monooxygenase1.14.130.445
2hjrAPRMalate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase/0.445
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.445
2vwqNAPGlucose 1-dehydrogenase/0.445
2wsbNADGalactitol dehydrogenase/0.445
2y0mACOHistone acetyltransferase KAT8/0.445
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.445
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.445
3fzwEQUSteroid Delta-isomerase5.3.3.10.445
3gkjHC3Niemann-Pick C1 protein/0.445
3gwdNAPCyclohexanone monooxygenase/0.445
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.445
3imgBZ2Pantothenate synthetase6.3.2.10.445
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.445
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.445
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.445
3pj8404Cyclin-dependent kinase 22.7.11.220.445
3rpqCMPcAMP-activated global transcriptional regulator CRP/0.445
3ssmSAHMycinamicin VI 2''-O-methyltransferase/0.445
3w5hFADNADH-cytochrome b5 reductase 31.6.2.20.445
3zuyTCHTransporter/0.445
4ajj88RL-lactate dehydrogenase A chain1.1.1.270.445
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.445
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.445
4djaFAD(6-4) photolyase/0.445
4ehuANP2-hydroxyisocaproyl-CoA dehydratase activator/0.445
4eox0S5Peptide deformylase/0.445
4g2fC07Ephrin type-A receptor 32.7.10.10.445
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.445
4kp8E1GCarbonic anhydrase 124.2.1.10.445
4kwhNAPReductase homolog/0.445
4m4922YL-lactate dehydrogenase A chain1.1.1.270.445
4q71FADBifunctional protein PutA/0.445
4r8hSP1cAMP-activated global transcriptional regulator CRP/0.445
4yagNAIC alpha-dehydrogenase/0.445
1ai9NDPDihydrofolate reductase1.5.1.30.444
1blzACVIsopenicillin N synthase1.21.3.10.444
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.444
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
1l5l7RPNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.444
1me6IVSPlasmepsin-23.4.23.390.444
1rfuADPPyridoxal kinase2.7.1.350.444
1rq1FADEndoplasmic oxidoreductin-11.8.40.444
1tojHCIAspartate aminotransferase2.6.1.10.444
1ur5NADMalate dehydrogenase/0.444
1yqzCOACoenzyme A disulfide reductase/0.444
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.444
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.444
2mwgFMNBlue-light photoreceptor/0.444
2npxNADNADH peroxidase1.11.1.10.444
2ph6712Beta-secretase 13.4.23.460.444
2yvgNADFerredoxin reductase/0.444
2zuiCAMCamphor 5-monooxygenase1.14.15.10.444
3b2eADPATPase GET3/0.444
3br3ETHTH-type transcriptional regulator QacR/0.444
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.444
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.444
3gonANPPhosphomevalonate kinase/0.444
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3mdvCL6Cholesterol 24-hydroxylase/0.444
3mjeNDPAmphB/0.444
3n0hTOPDihydrofolate reductase1.5.1.30.444
3nxxNDPDihydrofolate reductase1.5.1.30.444
3s79ASDAromatase1.14.14.140.444
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.444
4fod0UVALK tyrosine kinase receptor2.7.10.10.444
4i9h1E4L-lactate dehydrogenase A chain1.1.1.270.444
4okw198Androgen receptor/0.444
4rosAPRMalate dehydrogenase/0.444
4y0kNAPAntE/0.444
5cp4CAMCamphor 5-monooxygenase1.14.15.10.444
1f5nGNPGuanylate-binding protein 1/0.443
1g4tFTPThiamine-phosphate synthase/0.443
1levCLIFructose-1,6-bisphosphatase 13.1.3.110.443
1lf2R37Plasmepsin-23.4.23.390.443
1ml6GBXGlutathione S-transferase A22.5.1.180.443
1ra3MTXDihydrofolate reductase1.5.1.30.443
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.443
1u1f183Uridine phosphorylase2.4.2.30.443
1uumAFIDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.443
1xddAAYIntegrin alpha-L/0.443
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.443
2dxwSAHDiphthine synthase/0.443
2e15SAHDiphthine synthase/0.443
2e8hSAHDiphthine synthase/0.443
2eglSAHDiphthine synthase/0.443
2ek4SAHDiphthine synthase/0.443
2ekaSAHDiphthine synthase/0.443
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.443
2iviACWIsopenicillin N synthase1.21.3.10.443
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.443
2owvSAHDiphthine synthase/0.443
2pcaSAHDiphthine synthase/0.443
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.443
2vrbNAPTriphenylmethane reductase/0.443
2w3bNDPDihydrofolate reductase1.5.1.30.443
3bv2P38Mitogen-activated protein kinase 14/0.443
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3fpzAHZThiamine thiazole synthase/0.443
3ijdC2FMethylenetetrahydrofolate reductase/0.443
3k8t2A5Ribonucleoside-diphosphate reductase large chain 11.17.4.10.443
3mjrAC2Deoxycytidine kinase2.7.1.740.443
3oht1N1Mitogen-activated protein kinase/0.443
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3r0tFU9Casein kinase II subunit alpha2.7.11.10.443
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.443
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.443
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.443
4c2uANPDNA helicase/0.443
4chqCWUIntegrase/0.443
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.443
4gh5NADShort-chain dehydrogenase/reductase SDR/0.443
4kb81QOCasein kinase I isoform delta2.7.11.10.443
4lb2DM5Serum albumin/0.443
4riyADPEpidermal growth factor receptor2.7.10.10.443
4tvbNADHomospermidine synthase2.5.1.440.443
4wxg2BOSerine hydroxymethyltransferase/0.443
4y3zF41Endothiapepsin3.4.23.220.443
5bt9NAP3-oxoacyl-(Acyl-carrier-protein) reductase/0.443
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
5jlaNADPutative short-chain dehydrogenase/reductase/0.443
1bwsNDPGDP-L-fucose synthase/0.442
1cbqRE9Cellular retinoic acid-binding protein 2/0.442
1cjvFOKAdenylate cyclase type 2/0.442
1cjvFOKAdenylate cyclase type 5/0.442
1gebCAMCamphor 5-monooxygenase1.14.15.10.442
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.442
1hfqMOTDihydrofolate reductase1.5.1.30.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1iwiCAMCamphor 5-monooxygenase1.14.15.10.442
1l4gNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.442
1nhhANPDNA mismatch repair protein MutL/0.442
1uxjNADMalate dehydrogenase/0.442
1x7hNDPPutative ketoacyl reductase1.3.10.442
2avxHTFRegulatory protein SdiA/0.442
2az93TLGag-Pol polyprotein3.4.23.160.442
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.442
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.442
2oapANPType II secretion system protein (GspE-2)/0.442
2owkSAHDiphthine synthase/0.442
2p2mPRXAcetyl-coenzyme A synthetase/0.442
2pb6SAHDiphthine synthase/0.442
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
2xvw9NRSerum albumin/0.442
2xyuQ9GEphrin type-A receptor 42.7.10.10.442
3a6rFMNFMN-binding protein/0.442
3adaNADSubunit alpha of sarocosine oxidase/0.442
3awhFMNFMN-binding protein/0.442
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.442
3cgbCOACoenzyme A disulfide reductase/0.442
3eksCY9Actin-5C/0.442
3fr4F8AFatty acid-binding protein, adipocyte/0.442
3fr5I4AFatty acid-binding protein, adipocyte/0.442
3ik6HCZGlutamate receptor 2/0.442
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.442
3kytHC2Nuclear receptor ROR-gamma/0.442
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.442
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.442
3pvt3HC1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.442
3r4pFU7Heat shock protein HSP 90-alpha/0.442
3s2v3HUGlutamate receptor ionotropic, kainate 1/0.442
3wagTYDGlycosyltransferase/0.442
3zhyFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.442
3zksWZVBeta-secretase 23.4.23.450.442
4ap1NAPSteroid monooxygenase/0.442
4b3aTACTetracycline repressor protein class D/0.442
4b4vL34Bifunctional protein FolD/0.442
4dfrMTXDihydrofolate reductase1.5.1.30.442
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4g3rCAMCamphor 5-monooxygenase1.14.15.10.442
4jk3NADUncharacterized protein/0.442
4lpb1YPDNA topoisomerase 4 subunit B/0.442
4qaiFMNNADPH dehydrogenase/0.442
4ys22BAUncharacterized protein/0.442
5fwnNAPPutative dehydrogenase/0.442
1cnfFADNitrate reductase [NADH]1.7.1.10.441
1ep1FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.441
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.441
1nzdUPGDNA beta-glucosyltransferase/0.441
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1rdwLARActin, alpha skeletal muscle/0.441
1v2hGUNPurine nucleoside phosphorylase2.4.2.10.441
1vceSAHDiphthine synthase/0.441
1z0dGDPRas-related protein Rab-5C/0.441
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.441
2cndFADNitrate reductase [NADH]1.7.1.10.441
2e07SAHDiphthine synthase/0.441
2eh2SAHDiphthine synthase/0.441
2ejvNADL-threonine 3-dehydrogenase/0.441
2ihvTPPN(2)-(2-carboxyethyl)arginine synthase/0.441
2jlbUDMUncharacterized protein/0.441
2ohjFMNType A flavoprotein FprA10.441
2p20PRXAcetyl-coenzyme A synthetase/0.441
2p2lGDPRas-related C3 botulinum toxin substrate 1/0.441
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.441
2vwx7X4Ephrin type-B receptor 42.7.10.10.441
2x06NADL-sulfolactate dehydrogenase/0.441
2zb3NDPProstaglandin reductase 21.3.1.480.441
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.441
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3ai3NDPNADPH-sorbose reductase/0.441
3bnkFMNFlavoredoxin/0.441
3c1y2BADNA integrity scanning protein DisA/0.441
3c4aFADProtodeoxyviolaceinate monooxygenase10.441
3ensENSCoagulation factor X3.4.21.60.441
3i0pNADMalate dehydrogenase, putative/0.441
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.441
3lsmSFDPyranose 2-oxidase/0.441
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.441
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.441
3mpt1GKMitogen-activated protein kinase 14/0.441
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.441
3r9uFADThioredoxin reductase/0.441
3rlp3RPHeat shock protein HSP 90-alpha/0.441
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.441
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.441
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.441
3vy5FMNFMN-binding protein/0.441
3wv9FEGHmd co-occurring protein HcgE/0.441
3zsvZSVIntegrase/0.441
4a86H35Major pollen allergen Bet v 1-A/0.441
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.441
4c6uTLG3-oxoacyl-ACP synthase/0.441
4cebZSVIntegrase/0.441
4egnTWOCytochrome P450/0.441
4fuj1U9Urokinase-type plasminogen activator3.4.21.730.441
4iyg1HUStrictosidine synthase4.3.3.20.441
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.441
4xgxADPFAD:protein FMN transferase/0.441
5a3cNADSIR2 family protein/0.441
5bu2ADPUncharacterized protein/0.441
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.441
5dmhADP3-oxo-tetronate kinase/0.441
1b8oIMHPurine nucleoside phosphorylase2.4.2.10.440
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.440
1cjkFOKAdenylate cyclase type 2/0.440
1cjkFOKAdenylate cyclase type 5/0.440
1dirNADDihydropteridine reductase1.5.1.340.440
1h62ANBPentaerythritol tetranitrate reductase/0.440
1lqdCMICoagulation factor X3.4.21.60.440
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.440
1obnASVIsopenicillin N synthase1.21.3.10.440
1q43CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.440
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1ra2FOLDihydrofolate reductase1.5.1.30.440
1ra8FOLDihydrofolate reductase1.5.1.30.440
1rb2FOLDihydrofolate reductase1.5.1.30.440
1s3uTQDDihydrofolate reductase1.5.1.30.440
1u2yGOXPancreatic alpha-amylase/0.440
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.440
1y4sADPChaperone protein HtpG/0.440
1zapA70Candidapepsin-23.4.23.240.440
1zys199Serine/threonine-protein kinase Chk12.7.11.10.440
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2br5SAHCephalosporin hydroxylase CmcI/0.440
2c4iBTNAvidin/0.440
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.440
2e17SAHDiphthine synthase/0.440
2ek3SAHDiphthine synthase/0.440
2fvc888Polyprotein/0.440
2g1o2IGRenin3.4.23.150.440
2g1r3IGRenin3.4.23.150.440
2hutSAHDiphthine synthase/0.440
2r8vACOAmino-acid acetyltransferase/0.440
2vkeTACTetracycline repressor protein class D/0.440
2ym2FADPhenylacetone monooxygenase1.14.13.920.440
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.440
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.440
3cgeCOACoenzyme A disulfide reductase/0.440
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.440
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.440
3gkiCLRNiemann-Pick C1 protein/0.440
3gviADPMalate dehydrogenase/0.440
3iphG11Mitogen-activated protein kinase 14/0.440
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.440
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.440
3pvcFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.440
3r83Z14Cyclin-dependent kinase 22.7.11.220.440
3s3vTOPDihydrofolate reductase1.5.1.30.440
3u9eCOALmo1369 protein/0.440
3up0D7SaceDAF-12/0.440
4cf1IY7Integrase/0.440
4cjeQ31Integrase/0.440
4cloNAPPteridine reductase/0.440
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.440
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.440
4jlm1NNDeoxycytidine kinase2.7.1.740.440
4k5p1OSM1 family aminopeptidase3.4.110.440
4lcjNADC-terminal-binding protein 2/0.440
4m83ERYOleandomycin glycosyltransferase2.4.10.440
4relKMPGlycosyltransferase/0.440
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.440
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.440
5kghACOPredicted acetyltransferase/0.440
6cp4CAMCamphor 5-monooxygenase1.14.15.10.440