sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 1.000 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.503 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.495 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.489 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.487 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.480 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.479 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.479 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.473 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.467 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.465 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.459 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.458 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.458 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.455 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.452 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.445 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.445 | |
| 4mit | GTP | Rho-related protein racC | / | 0.444 | |
| 4dvg | GSP | Rho family GTPase | / | 0.441 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.440 |