sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4gvq | N4M | Methenyltetrahydromethanopterin cyclohydrolase | 3.5.4.27 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4gvq | N4M | Methenyltetrahydromethanopterin cyclohydrolase | 3.5.4.27 | 1.000 | |
| 4gvs | F4M | Methenyltetrahydromethanopterin cyclohydrolase | 3.5.4.27 | 0.589 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.485 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.446 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.445 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.441 |