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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.60

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.601.000
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.774
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.656
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.600.649
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.642
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.636
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.618
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.616
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.599
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.586
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.444