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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4grb0XGCasein kinase II subunit alpha2.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4grb0XGCasein kinase II subunit alpha2.7.11.11.000
3q9xEMOCasein kinase II subunit alpha2.7.11.10.621
3u4uLNHCasein kinase II subunit alpha2.7.11.10.598
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.586
2pvlP55Casein kinase II subunit alpha2.7.11.10.568
3be9P04Casein kinase II subunit alpha2.7.11.10.568
5cvfATPCasein kinase II subunit alpha2.7.11.10.568
3at4CCKCasein kinase II subunit alpha2.7.11.10.561
2pvhP19Casein kinase II subunit alpha2.7.11.10.554
4anmWULCasein kinase II subunit alpha2.7.11.10.554
4dgmAGICasein kinase II subunit alpha2.7.11.10.553
2pvmP29Casein kinase II subunit alpha2.7.11.10.551
1m2pHNACasein kinase II subunit alpha2.7.11.10.550
4dgnLU2Casein kinase II subunit alpha2.7.11.10.549
3axwTIDCasein kinase II subunit alpha2.7.11.10.528
1om1IQACasein kinase II subunit alpha2.7.11.10.510
2yaaATPDeath-associated protein kinase 2/0.510
1pjkANPCasein kinase II subunit alpha2.7.11.10.503
5av2KMPDeath-associated protein kinase 12.7.11.10.503
4jia1K3Tyrosine-protein kinase JAK2/0.501
3mb714ICasein kinase II subunit alpha2.7.11.10.496
1dawANPCasein kinase II subunit alpha2.7.11.10.492
3lltANPProtein serine/threonine kinase-1/0.492
3pe2E1BCasein kinase II subunit alpha2.7.11.10.492
2zjwREFCasein kinase II subunit alpha2.7.11.10.489
5av3KMPDeath-associated protein kinase 12.7.11.10.489
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.478
3juhANPCasein kinase II subunit alpha2.7.11.10.477
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.473
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.469
2pvnP63Casein kinase II subunit alpha2.7.11.10.468
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.468
1jklANPDeath-associated protein kinase 12.7.11.10.467
4bcmT7ZCyclin-dependent kinase 22.7.11.220.466
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.466
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.464
3bqr4RBDeath-associated protein kinase 3/0.461
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.461
4hge15VTyrosine-protein kinase JAK2/0.461
3nux3NVCyclin-dependent kinase 62.7.11.220.460
2uzbC75Cyclin-dependent kinase 22.7.11.220.459
5e8ySTUTGF-beta receptor type-22.7.11.300.459
5dosATPAurora kinase A2.7.11.10.458
2w05FRTCyclin-dependent kinase 22.7.11.220.457
2ckeIQUDeath-associated protein kinase 2/0.455
4lfiGNPCasein kinase II subunit alpha2.7.11.10.455
4ez50RSCyclin-dependent kinase 62.7.11.220.454
4j95ACPFibroblast growth factor receptor 2/0.454
4hvi19STyrosine-protein kinase JAK32.7.10.20.452
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.452
2vu3LZECyclin-dependent kinase 22.7.11.220.451
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.451
1dayGNPCasein kinase II subunit alpha2.7.11.10.450
3begANPSRSF protein kinase 12.7.11.10.449
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.449
3qxpX64Cyclin-dependent kinase 22.7.11.220.449
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2fvdLIACyclin-dependent kinase 22.7.11.220.446
3i60E86Mitogen-activated protein kinase 12.7.11.240.446
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.446
1fvv107Cyclin-dependent kinase 22.7.11.220.445
2vv9IM9Cyclin-dependent kinase 22.7.11.220.445
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.445
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.444
4fv6E57Mitogen-activated protein kinase 12.7.11.240.444
4fv9E71Mitogen-activated protein kinase 12.7.11.240.444
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.443
3gu7ADPDeath-associated protein kinase 12.7.11.10.443
4qnyANPMitogen activated protein kinase, putative/0.442
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.440