sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 1.000 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.489 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.480 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.468 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.468 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.461 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.454 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.450 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.449 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.448 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.446 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.445 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.441 |