sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4gdy	0X1	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4gdy	0X1	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	1.000
4geb	0LD	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.596
4ge7	0K5	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.593
4ge4	0KE	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.530
4ge9	0L0	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.454