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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4gd40WSLysine-specific demethylase 4A1.14.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4gd40WSLysine-specific demethylase 4A1.14.111.000
3pdqKC6Lysine-specific demethylase 4A1.14.110.648
4bis8HQLysine-specific demethylase 4A1.14.110.592
2wwjY28Lysine-specific demethylase 4A/0.564
4lxlPD2Lysine-specific demethylase 4B1.14.110.560
3rvhHQ2Lysine-specific demethylase 4A1.14.110.559
2vd7PD2Lysine-specific demethylase 4A1.14.110.551
4d6qPD2Lysine-specific demethylase 4D1.14.110.514