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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ga8SBIAldo-keto reductase family 1 member B101.1.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4ga8SBIAldo-keto reductase family 1 member B101.1.11.000
2inzOHPAldose reductase1.1.1.210.612
2pdyFIDAldose reductase1.1.1.210.598
3ghsLDTAldose reductase1.1.1.210.593
2fz9ZSTAldose reductase1.1.1.210.587
2pdwFIDAldose reductase1.1.1.210.586
2fzdTOLAldose reductase1.1.1.210.583
3mb9ZSTAldose reductase1.1.1.210.582
3g5eQ74Aldose reductase1.1.1.210.580
1z3n3NAAldose reductase1.1.1.210.579
2i16LDTAldose reductase1.1.1.210.578
2iqdLPAAldose reductase1.1.1.210.578
2pdxZSTAldose reductase1.1.1.210.567
2f2kTGGAldose reductase1.1.1.210.565
2qxwLDTAldose reductase1.1.1.210.565
3ghrLDTAldose reductase1.1.1.210.564
1us0LDTAldose reductase1.1.1.210.560
3s3gTLTAldose reductase1.1.1.210.559
5liu388Aldo-keto reductase family 1 member B101.1.10.558
1ieiZESAldose reductase1.1.1.210.555
4gca2X9Aldose reductase1.1.1.210.555
2hvoZSTAldose reductase1.1.1.210.554
3u2cSUZAldose reductase1.1.1.210.554
2hvnZSTAldose reductase1.1.1.210.553
4gabFIDAldo-keto reductase family 1 member B101.1.10.553
1pwlBFIAldose reductase1.1.1.210.551
2iki388Aldose reductase1.1.1.210.551
2dv0ZSTAldose reductase1.1.1.210.546
1ah0SBIAldose reductase1.1.1.210.545
2fz8ZSTAldose reductase1.1.1.210.544
2pdg47DAldose reductase1.1.1.210.543
2hv5ZSTAldose reductase1.1.1.210.542
3m4h388Aldose reductase1.1.1.210.540
2ikj393Aldose reductase1.1.1.210.539
1az2NAPAldose reductase1.1.1.210.537
3lboLDTAldose reductase1.1.1.210.537
1ekoI84Aldose reductase1.1.1.210.536
3ld5LDTAldose reductase1.1.1.210.532
1z8962PAldose reductase1.1.1.210.528
2pdu393Aldose reductase1.1.1.210.527
3ghuLDTAldose reductase1.1.1.210.527
2i17LDTAldose reductase1.1.1.210.526
1el3I84Aldose reductase1.1.1.210.525
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.524
3lz5LDTAldose reductase1.1.1.210.524
1t40ID5Aldose reductase1.1.1.210.522
3lenZSTAldose reductase1.1.1.210.521
4yu153NAldose reductase1.1.1.210.520
3m64393Aldose reductase1.1.1.210.519
3mc5393Aldose reductase1.1.1.210.519
2pdn47DAldose reductase1.1.1.210.518
2w6cBM4Acetylcholinesterase3.1.1.70.517
3v36NAPAldose reductase1.1.1.210.515
2agtFIDAldose reductase1.1.1.210.514
2duzZSTAldose reductase1.1.1.210.513
1h22E10Acetylcholinesterase3.1.1.70.512
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.512
2pdp393Aldose reductase1.1.1.210.512
3t423T4Aldose reductase1.1.1.210.511
3v35NTIAldose reductase1.1.1.210.508
2acsNAPAldose reductase1.1.1.210.507
3lqlLDTAldose reductase1.1.1.210.506
1q84TZ4Acetylcholinesterase3.1.1.70.505
2pdc393Aldose reductase1.1.1.210.504
2duxZSTAldose reductase1.1.1.210.503
2cekN8TAcetylcholinesterase3.1.1.70.502
2evmFC2Methionine aminopeptidase/0.502
1e66HUXAcetylcholinesterase3.1.1.70.501
1t41ID5Aldose reductase1.1.1.210.501
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.500
2ikhLITAldose reductase1.1.1.210.500
3pkdY10Methionine aminopeptidase 2/0.498
2j3qTFLAcetylcholinesterase3.1.1.70.497
2pdmZSTAldose reductase1.1.1.210.495
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.495
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.493
2gyuHI6Acetylcholinesterase3.1.1.70.492
2pdq47DAldose reductase1.1.1.210.492
2xi4AFTAcetylcholinesterase3.1.1.70.492
4m0f1YKAcetylcholinesterase3.1.1.70.492
2fzbTOLAldose reductase1.1.1.210.491
2pd5ZSTAldose reductase1.1.1.210.491
4ey7E20Acetylcholinesterase3.1.1.70.491
1d3dBZTProthrombin3.4.21.50.490
1u65CP0Acetylcholinesterase3.1.1.70.490
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.490
1eveE20Acetylcholinesterase3.1.1.70.489
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.489
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.489
2nvcITAAldose reductase1.1.1.210.489
2pdbZSTAldose reductase1.1.1.210.489
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.489
1qtiGNTAcetylcholinesterase3.1.1.70.488
1w4lGL8Acetylcholinesterase3.1.1.70.488
2pb1NFGGlucan 1,3-beta-glucosidase/0.488
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.488
3zv7NHGAcetylcholinesterase3.1.1.70.488
4lcw1VYMajor histocompatibility complex class I-related gene protein/0.486
4n3l2FNProthrombin3.4.21.50.486
3uweVJJAldo-keto reductase family 1 member C3/0.485
4pnmNU1Tankyrase-22.4.2.300.485
2xugTZ4Acetylcholinesterase3.1.1.70.484
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.484
1zgcA2EAcetylcholinesterase3.1.1.70.483
2ea2F77Methionine aminopeptidase 2/0.483
3p2vDOYAldose reductase1.1.1.210.483
4jtrIZPAldo-keto reductase family 1 member C2/0.483
1w6rGNTAcetylcholinesterase3.1.1.70.482
2evcFC3Methionine aminopeptidase/0.482
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.482
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.482
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.482
1w87FADFerredoxin--NADP reductase1.18.1.20.481
4p9dTMPDeoxycytidylate deaminase/0.481
2q92B23Methionine aminopeptidase/0.480
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.479
1ry0PG2Aldo-keto reductase family 1 member C3/0.478
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.478
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.478
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.478
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.477
1ut6A8NAcetylcholinesterase3.1.1.70.477
2gg8U15Methionine aminopeptidase/0.477
2pdiZSTAldose reductase1.1.1.210.477
3h4gFIDAlcohol dehydrogenase [NADP(+)]1.1.1.20.477
4jqaID8Aldo-keto reductase family 1 member C2/0.476
1zgbA1EAcetylcholinesterase3.1.1.70.475
2q94A04Methionine aminopeptidase/0.475
2xuhTZ4Acetylcholinesterase3.1.1.70.475
4ey6GNTAcetylcholinesterase3.1.1.70.475
1rkwPNTHTH-type transcriptional regulator QacR/0.474
1votHUPAcetylcholinesterase3.1.1.70.474
4fam0SZAldo-keto reductase family 1 member C3/0.474
1rxjBNIStreptavidin/0.473
1u08PLPMethionine aminotransferase/0.473
2bjsACVIsopenicillin N synthase1.21.3.10.473
2ckmAA7Acetylcholinesterase3.1.1.70.473
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.473
1ry8RUTAldo-keto reductase family 1 member C3/0.472
1s36CEIObelin/0.472
1yw9A84Methionine aminopeptidase 2/0.472
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.472
2xltNA0Putative flavin-containing monooxygenase/0.472
3ai0PNWBeta-glucosidase/0.472
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.472
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.472
4araC56Acetylcholinesterase3.1.1.70.472
2p99YE6Methionine aminopeptidase/0.471
2xufTZ4Acetylcholinesterase3.1.1.70.471
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.471
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.471
3iu8T03Methionine aminopeptidase 2/0.471
3mauPLRPutative sphingosine-1-phosphate lyase/0.471
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.471
2xujTZ5Acetylcholinesterase3.1.1.70.470
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.470
1zuaTOLAldo-keto reductase family 1 member B101.1.10.469
2ct8MSPMethionine--tRNA ligase6.1.1.100.469
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.469
4wljIK2Kynurenine--oxoglutarate transaminase 12.6.1.70.469
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.468
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.468
3klbFMNUncharacterized protein/0.468
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.468
4arbC57Acetylcholinesterase3.1.1.70.468
4j7gTRHPCZA361.3/0.468
1e1fPSG4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.467
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.467
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.466
1q83TZ5Acetylcholinesterase3.1.1.70.466
2fahGDPPhosphoenolpyruvate carboxykinase [GTP], mitochondrial4.1.1.320.466
4b7zQ4QAcetylcholinesterase3.1.1.70.466
5dsg0HKMuscarinic acetylcholine receptor M4/0.466
1lkeDOGBilin-binding protein/0.465
1tkcM6TTransketolase 12.2.1.10.465
1x2bSTXProline iminopeptidase3.4.11.50.465
1zq5E04Aldo-keto reductase family 1 member C3/0.465
2a3bCFFEndochitinase B13.2.1.140.465
2xukTZ5Acetylcholinesterase3.1.1.70.465
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
4jq3ZOMAldo-keto reductase family 1 member C2/0.465
1dx6GNTAcetylcholinesterase3.1.1.70.464
1gpnHUBAcetylcholinesterase3.1.1.70.464
2ipjFFAAldo-keto reductase family 1 member C2/0.464
2w3mFOLDihydrofolate reductase1.5.1.30.464
3e4vFMNUncharacterized protein/0.464
3fx4FX4Alcohol dehydrogenase [NADP(+)]1.1.1.20.464
3zj6VM2Raucaffricine-O-beta-D-glucosidase3.2.1.1250.464
4jq4IMNAldo-keto reductase family 1 member C2/0.464
4jtrIBPAldo-keto reductase family 1 member C2/0.464
1c23MPHMethionine aminopeptidase/0.463
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.463
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.463
2jf0HBPAcetylcholinesterase3.1.1.70.463
2jl1NAPTriphenylmethane reductase/0.463
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.463
3vilSA0Beta-glucosidase/0.463
4fliY16Methionine aminopeptidase 1/0.463
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.463
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.463
4tmcFMNOld yellow enzyme/0.463
1vfsDCSAlanine racemase/0.462
1xnzFCDMethionine aminopeptidase/0.462
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.462
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.462
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.462
3pkcY08Methionine aminopeptidase 2/0.462
4flkY10Methionine aminopeptidase 1/0.462
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.461
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.461
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.461
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.461
2pdfZSTAldose reductase1.1.1.210.461
2pdlTOLAldose reductase1.1.1.210.461
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.461
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.461
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.461
4azaMGOEukaryotic translation initiation factor 4E/0.461
4mqt2CUMuscarinic acetylcholine receptor M2/0.461
1hfrMOTDihydrofolate reductase1.5.1.30.460
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.460
2ha6SCKAcetylcholinesterase3.1.1.70.460
2vqqTFGHistone deacetylase 43.5.1.980.460
2xupTZ5Acetylcholinesterase3.1.1.70.460
2zs9ADPPantothenate kinase2.7.1.330.460
3br3ETHTH-type transcriptional regulator QacR/0.460
3t0kDCQSulfide-quinone reductase/0.460
3wqmB29Diterpene synthase3.1.7.80.460
1d3pBT3Prothrombin3.4.21.50.459
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.459
1odcA8BAcetylcholinesterase3.1.1.70.459
2fjeFADAdenylylsulfate reductase, subunit A (AprA)/0.459
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.459
2is72CLAldose reductase1.1.1.210.459
2q93B21Methionine aminopeptidase/0.459
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.459
2xuqTZ4Acetylcholinesterase3.1.1.70.459
3c1oNAPEugenol synthase/0.459
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.459
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.458
2gywOBIAcetylcholinesterase3.1.1.70.458
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.458
3g5iDNBPyrimidine-specific ribonucleoside hydrolase RihA/0.458
4epq0RRPoly(ADP-ribose) glycohydrolase/0.458
4ikuSHXMethionine aminopeptidase 1/0.458
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.458
1mlzPLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.457
1mrqSTRAldo-keto reductase family 1 member C1/0.457
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.457
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.457
1ah3TOLAldose reductase1.1.1.210.456
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.456
3iu7FCDMethionine aminopeptidase 2/0.456
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.456
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.456
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
5cxv0HKMuscarinic acetylcholine receptor M1/0.456
1frbZSTAldose reductase-related protein 2/0.455
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.455
1jf0CZHObelin/0.455
1s7gNADNAD-dependent protein deacylase 2/0.455
2gg0U11Methionine aminopeptidase/0.455
2ociTYCValacyclovir hydrolase3.10.455
2pdkSBIAldose reductase1.1.1.210.455
2qw8NAPEugenol synthase 11.1.1.3180.455
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3irhDTPHD domain protein/0.455
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.455
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.455
4kfjFOLDihydrofolate reductase1.5.1.30.455
4kn0MTXFolate receptor beta/0.455
1k02FMNNADPH dehydrogenase 11.6.99.10.454
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.454
2aj4ANPGalactokinase2.7.1.60.454
2gg3U13Methionine aminopeptidase/0.454
2gg9U16Methionine aminopeptidase/0.454
2wmdZZ0NmrA-like family domain-containing protein 1/0.454
2xuoTZ4Acetylcholinesterase3.1.1.70.454
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.453
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.453
3bi6396Wee1-like protein kinase2.7.10.20.453
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3geyP34Poly [ADP-ribose] polymerase 152.4.2.300.453
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.453
3nt2NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.453
3pkeY10Methionine aminopeptidase 2/0.453
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.453
4bj9UHBTankyrase-22.4.2.300.453
4m6kFOLDihydrofolate reductase1.5.1.30.453
4q7f3D1Uncharacterized protein/0.453
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.453
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.452
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.452
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.452
1t7o152Carnitine O-acetyltransferase2.3.1.70.452
1uhhCZPAequorin-2/0.452
2b8jADNClass B acid phosphatase3.1.3.20.452
2qimZEAClass 10 plant pathogenesis-related protein/0.452
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3r8hZOMAldo-keto reductase family 1 member C3/0.452
4f3gKAIGlutamate receptor 3/0.452
4iktTFVMethionine aminopeptidase 1/0.452
4je5PLPAromatic/aminoadipate aminotransferase 12.6.1.390.452
4wbdADPPutative cysteine ligase BshC/0.452
1m2xMCOMetallo-beta-lactamase type 2/0.451
1qv0CZHObelin/0.451
2g1a5HGClass B acid phosphatase3.1.3.20.451
2gvcFADThiol-specific monooxygenase1.14.130.451
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.451
3htjETEbrA repressor/0.451
3nxtD2EDihydrofolate reductase1.5.1.30.451
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.451
4dz5NAPAldo-keto reductase family 1 member C3/0.451
4m6l21VDihydrofolate reductase1.5.1.30.451
1jumBERHTH-type transcriptional regulator QacR/0.450
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.450
1lnmDTXBilin-binding protein/0.450
1obnASVIsopenicillin N synthase1.21.3.10.450
1r5gAO1Methionine aminopeptidase 2/0.450
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.450
2ipw2CLAldose reductase1.1.1.210.450
2wzySQXSoluble acetylcholine receptor/0.450
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.450
3e6eDCSAlanine racemase/0.450
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.450
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.450
3qwc98PProthrombin3.4.21.50.450
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3voiRCBGlucanase/0.450
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.450
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.449
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.449
2bd0NAPSepiapterin reductase/0.449
2cboTH2Neocarzinostatin/0.449
2io6330Wee1-like protein kinase2.7.10.20.449
2zevIPEGeranylgeranyl pyrophosphate synthase/0.449
3cv6HXSAldo-keto reductase family 1 member C21/0.449
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.449
3pkaY02Methionine aminopeptidase 2/0.449
3ugrIMNAldo-keto reductase family 1 member C3/0.449
4bjbP34Tankyrase-22.4.2.300.449
4fljY08Methionine aminopeptidase 1/0.449
5ds309LPoly [ADP-ribose] polymerase 12.4.2.300.449
1ef3FIDAldose reductase1.1.1.210.448
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.448
1vftDCSAlanine racemase/0.448
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.448
2gmvUN8Phosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.448
2pdh47DAldose reductase1.1.1.210.448
2xlpFADPutative flavin-containing monooxygenase/0.448
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3f0aACOSpermidine N(1)-acetyltransferase/0.448
3l7gM44Xaa-Pro dipeptidase3.4.13.90.448
3rtnRTNBeta-secretase 13.4.23.460.448
4b66NAPL-ornithine N(5)-monooxygenase/0.448
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.448
4psbGA3Cytokinin-specific binding protein/0.448
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1isjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.447
1pd8CO4Dihydrofolate reductase1.5.1.30.447
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.447
2acqNAPAldose reductase1.1.1.210.447
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.447
2hzqSTRApolipoprotein D/0.447
2pd9FIDAldose reductase1.1.1.210.447
2vrjNCWBeta-glucosidase A3.2.1.210.447
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.447
3rsv3RSBeta-secretase 13.4.23.460.447
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.447
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.447
4hlf15ZTankyrase-22.4.2.300.447
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.447
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.447
4u140HKMuscarinic acetylcholine receptor M3/0.447
1acjTHAAcetylcholinesterase3.1.1.70.446
1fw0KAIGlutamate receptor 2/0.446
1z71L17Prothrombin3.4.21.50.446
2wm3NFLNmrA-like family domain-containing protein 1/0.446
2zhw12UProthrombin3.4.21.50.446
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
3r8gIZPAldo-keto reductase family 1 member C3/0.446
3sxjSAMPutative methyltransferase/0.446
3to3ATPPetrobactin biosynthesis protein AsbB/0.446
4bamMM9Prothrombin3.4.21.50.446
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.446
1jdzFMBPurine nucleoside phosphorylase/0.445
1nzq162Prothrombin3.4.21.50.445
1rpwDIDHTH-type transcriptional regulator QacR/0.445
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.445
2ejzSAHDiphthine synthase/0.445
2ga2A19Methionine aminopeptidase 2/0.445
2ggbU17Methionine aminopeptidase/0.445
2ycnP61Tyrosine phenol-lyase4.1.99.20.445
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.445
3q9bB3NAcetylpolyamine amidohydrolase/0.445
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.445
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.445
4bfuZVUPantothenate kinase2.7.1.330.445
4jzr4JREgl nine homolog 1/0.445
4kn2LYAFolate receptor beta/0.445
4y1bNAPAntE/0.445
1bk0ACVIsopenicillin N synthase1.21.3.10.444
1ffyMRCIsoleucine--tRNA ligase6.1.1.50.444
1h60STRPentaerythritol tetranitrate reductase/0.444
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1r58AO5Methionine aminopeptidase 2/0.444
1z5uCMPClass B acid phosphatase/0.444
1zrb062Prothrombin3.4.21.50.444
2e82IM3D-amino-acid oxidase1.4.3.30.444
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.444
2gbyBRNHTH-type transcriptional regulator QacR/0.444
3c1kT15Prothrombin3.4.21.50.444
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3gxfIFMGlucosylceramidase3.2.1.450.444
3h0bB35Beta-secretase 13.4.23.460.444
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3ptqNFGBeta-glucosidase 12/0.444
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.444
4b1jA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.444
4fllYZ6Methionine aminopeptidase 1/0.444
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.444
4to2DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.444
3vw7VPXProteinase-activated receptor 1/0.444
3uonQNBMuscarinic acetylcholine receptor M2/0.444
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.443
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.443
1ve3SAMUncharacterized protein/0.443
1x2eATXProline iminopeptidase3.4.11.50.443
2f3815MAldo-keto reductase family 1 member C3/0.443
2pdj393Aldose reductase1.1.1.210.443
2po3T4K4-dehydrase/0.443
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3w5uFADFerredoxin/0.443
4bueJQFTankyrase-22.4.2.300.443
4hlh20DTankyrase-22.4.2.300.443
4hrqAZGCytidine and deoxycytidylate deaminase zinc-binding region/0.443
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4m0cFMNFMN-dependent NADH-azoreductase 1/0.443
4wevSUZAldo-keto reductase family 1 member B101.1.10.443
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.443
1hb3SCVIsopenicillin N synthase1.21.3.10.442
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.442
2aotSAHHistamine N-methyltransferase2.1.1.80.442
2bfaCB3Pteridine reductase 11.5.1.330.442
2wp9CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.442
2wp9CBESuccinate dehydrogenase cytochrome b556 subunit/0.442
3i9kNADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase3.2.2.60.442
3iu9T07Methionine aminopeptidase 2/0.442
3qftFADNADPH--cytochrome P450 reductase/0.442
4ixt1H1Halohydrin dehalogenase/0.442
4l341VGTankyrase-22.4.2.300.442
4tjy3GNTankyrase-22.4.2.300.442
4uugPXGBranched-chain amino acid aminotransferase, putative/0.442
5a4vQUEGlutathione S-transferase F22.5.1.180.442
5jdzSAHMethyl transferase/0.442
1amoFADNADPH--cytochrome P450 reductase/0.441
1ohjCOPDihydrofolate reductase1.5.1.30.441
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.441
1s1rNAPAldo-keto reductase family 1 member C3/0.441
2g6pHM2Methionine aminopeptidase 1/0.441
2hdjNDPAldo-keto reductase family 1 member C2/0.441
2vq7NAPPutative flavin-containing monooxygenase/0.441
2y6fM9FIsopenicillin N synthase1.21.3.10.441
3b9gIMHIAG-nucleoside hydrolase/0.441
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.441
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3fsjD7KBenzoylformate decarboxylase4.1.1.70.441
3g70A5TRenin3.4.23.150.441
3ghtLDTAldose reductase1.1.1.210.441
3h7rNAPAldo-keto reductase family 4 member C8/0.441
3uelA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.441
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
3w4k3LDD-amino-acid oxidase1.4.3.30.441
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.441
4jtqFLPAldo-keto reductase family 1 member C2/0.441
4xo7ASDAldo-keto reductase family 1 member C2/0.441
4xt8TMQPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.441
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.441
5jqhCAUBeta-2 adrenergic receptor/0.441
1ej3CZHAequorin-2/0.440
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.440
1vf3GDNGlutathione S-transferase 32.5.1.180.440
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2ea4F79Methionine aminopeptidase 2/0.440
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2v8pCDP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.440
2wo7ASVIsopenicillin N synthase1.21.3.10.440
2wu4HBPAcetylcholinesterase3.1.1.70.440
3af0GDPPantothenate kinase2.7.1.330.440
3dr7GPDGDP-perosamine synthase/0.440
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.440
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.440
3h3qH13Collagen type IV alpha-3-binding protein/0.440
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3qgf46FGenome polyprotein2.7.7.480.440
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.440
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.440
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.440
4j7hTRHPCZA361.3/0.440
4kn104JFolate receptor beta/0.440
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
4n9qFMNFMN-dependent NADH-azoreductase 1/0.440
4nv7COAArylamine N-acetyltransferase/0.440