sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4g6h	FAD	Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial	1.6.5.9

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4g6h	FAD	Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial	1.6.5.9	1.000
4g73	FAD	Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial	1.6.5.9	0.645
4g74	FAD	Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial	1.6.5.9	0.623
4g6g	FAD	Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial	1.6.5.9	0.603
4gav	FAD	Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial	1.6.5.9	0.564