Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fyn0VETyrosine-protein kinase SYK2.7.10.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4fyn0VETyrosine-protein kinase SYK2.7.10.21.000
4fz60VGTyrosine-protein kinase SYK2.7.10.20.589
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.531
2j0m4STFocal adhesion kinase 12.7.10.20.487
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.459
3lq5SLQCyclin-dependent kinase 92.7.11.220.455
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.451
3vf9477Tyrosine-protein kinase SYK2.7.10.20.448
3emg685Tyrosine-protein kinase SYK2.7.10.20.444