sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4ft8	CMP	cAMP-activated global transcriptional regulator CRP

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4ft8	CMP	cAMP-activated global transcriptional regulator CRP	/	1.000
2gzw	CMP	cAMP-activated global transcriptional regulator CRP	/	0.624
4r8h	SP1	cAMP-activated global transcriptional regulator CRP	/	0.617
4i01	CMP	cAMP-activated global transcriptional regulator CRP	/	0.613
1zrd	CMP	cAMP-activated global transcriptional regulator CRP	/	0.607
1zrc	CMP	cAMP-activated global transcriptional regulator CRP	/	0.601
4hzf	CMP	cAMP-activated global transcriptional regulator CRP	/	0.597
4i09	CMP	cAMP-activated global transcriptional regulator CRP	/	0.576
3kcc	CMP	cAMP-activated global transcriptional regulator CRP	/	0.568
3rou	CMP	cAMP-activated global transcriptional regulator CRP	/	0.568
4i0a	CMP	cAMP-activated global transcriptional regulator CRP	/	0.565
3ryp	CMP	cAMP-activated global transcriptional regulator CRP	/	0.559
1i5z	CMP	cAMP-activated global transcriptional regulator CRP	/	0.552
3rpq	CMP	cAMP-activated global transcriptional regulator CRP	/	0.536
1ruo	CMP	cAMP-activated global transcriptional regulator CRP	/	0.524
3qop	CMP	cAMP-activated global transcriptional regulator CRP	/	0.485
4n9i	PCG	Catabolite expression activator	/	0.458
1phe	PIY	Camphor 5-monooxygenase	1.14.15.1	0.443
3sp6	IL2	Peroxisome proliferator-activated receptor alpha	/	0.442