sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4ft4	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4ft4	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	1.000
1skm	SAH	Modification methylase HhaI	2.1.1.37	0.512
1fjx	SAH	Modification methylase HhaI	2.1.1.37	0.494
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.489
2hmy	SAM	Modification methylase HhaI	2.1.1.37	0.485
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.482
2i9k	SAH	Modification methylase HhaI	2.1.1.37	0.476
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.473
2uyh	SAH	Modification methylase HhaI	2.1.1.37	0.455
10mh	SAH	Modification methylase HhaI	2.1.1.37	0.452
2z6u	SAH	Modification methylase HhaI	2.1.1.37	0.445