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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fkv61KCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4fkv61KCyclin-dependent kinase 22.7.11.221.000
3lfnA27Cyclin-dependent kinase 22.7.11.220.629
1y91CT9Cyclin-dependent kinase 22.7.11.220.578
4ek816KCyclin-dependent kinase 22.7.11.220.577
1oitHDTCyclin-dependent kinase 22.7.11.220.573
3lfqA28Cyclin-dependent kinase 22.7.11.220.567
2r3jSCJCyclin-dependent kinase 22.7.11.220.563
2vv9IM9Cyclin-dependent kinase 22.7.11.220.560
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.558
3rak03ZCyclin-dependent kinase 22.7.11.220.558
3s1h56ZCyclin-dependent kinase 22.7.11.220.558
3r8lZ30Cyclin-dependent kinase 22.7.11.220.555
2w17I19Cyclin-dependent kinase 22.7.11.220.553
1pxlCK4Cyclin-dependent kinase 22.7.11.220.547
2b52D42Cyclin-dependent kinase 22.7.11.220.545
3rjc06ZCyclin-dependent kinase 22.7.11.220.544
3rni21ZCyclin-dependent kinase 22.7.11.220.537
3qu0X40Cyclin-dependent kinase 22.7.11.220.533
3rk708ZCyclin-dependent kinase 22.7.11.220.533
1ke5LS1Cyclin-dependent kinase 22.7.11.220.531
2w1hL0FCyclin-dependent kinase 22.7.11.220.530
2xmyCDKCyclin-dependent kinase 22.7.11.220.529
4fkr45KCyclin-dependent kinase 22.7.11.220.528
1aq1STUCyclin-dependent kinase 22.7.11.220.526
1pxoCK7Cyclin-dependent kinase 22.7.11.220.525
4acm7YGCyclin-dependent kinase 22.7.11.220.525
3s2pPMUCyclin-dependent kinase 22.7.11.220.523
3sw418KCyclin-dependent kinase 22.7.11.220.523
1ykr628Cyclin-dependent kinase 22.7.11.220.522
3rpv26ZCyclin-dependent kinase 22.7.11.220.522
1g5sI17Cyclin-dependent kinase 22.7.11.220.520
3qtzX42Cyclin-dependent kinase 22.7.11.220.520
3rmf20ZCyclin-dependent kinase 22.7.11.220.520
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.519
3ezvEZVCyclin-dependent kinase 22.7.11.220.519
2btsU32Cyclin-dependent kinase 22.7.11.220.517
3r1yX76Cyclin-dependent kinase 22.7.11.220.517
2a0cCK9Cyclin-dependent kinase 22.7.11.220.516
4fks46KCyclin-dependent kinase 22.7.11.220.516
2r3lSCWCyclin-dependent kinase 22.7.11.220.515
4fkq42KCyclin-dependent kinase 22.7.11.220.515
2c6o4SPCyclin-dependent kinase 22.7.11.220.513
4fkg4CKCyclin-dependent kinase 22.7.11.220.513
2r3kSCQCyclin-dependent kinase 22.7.11.220.511
3r9oZ71Cyclin-dependent kinase 22.7.11.220.511
2btrU73Cyclin-dependent kinase 22.7.11.220.510
3qtxX43Cyclin-dependent kinase 22.7.11.220.510
4fki09KCyclin-dependent kinase 22.7.11.220.509
1oirHDYCyclin-dependent kinase 22.7.11.220.508
2uznC96Cyclin-dependent kinase 22.7.11.220.507
4fkpLS5Cyclin-dependent kinase 22.7.11.220.505
1ckpPVBCyclin-dependent kinase 22.7.11.220.504
4fkt48KCyclin-dependent kinase 22.7.11.220.503
3rk909ZCyclin-dependent kinase 22.7.11.220.502
4fko20KCyclin-dependent kinase 22.7.11.220.502
4fkw62KCyclin-dependent kinase 22.7.11.220.500
2w06FRVCyclin-dependent kinase 22.7.11.220.499
4ek610KCyclin-dependent kinase 22.7.11.220.499
1pxmCK5Cyclin-dependent kinase 22.7.11.220.498
2vtsLZCCyclin-dependent kinase 22.7.11.220.498
2vtrLZBCyclin-dependent kinase 22.7.11.220.497
1gih1PUCyclin-dependent kinase 22.7.11.220.496
3r83Z14Cyclin-dependent kinase 22.7.11.220.496
3wblPDYCyclin-dependent kinase 22.7.11.220.495
1gii1PUCyclin-dependent kinase 22.7.11.220.494
2b53D23Cyclin-dependent kinase 22.7.11.220.493
3iggEFQCyclin-dependent kinase 22.7.11.220.493
1fvv107Cyclin-dependent kinase 22.7.11.220.492
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.492
3qtrX36Cyclin-dependent kinase 22.7.11.220.492
3qtuX44Cyclin-dependent kinase 22.7.11.220.492
1ke6LS2Cyclin-dependent kinase 22.7.11.220.491
3sw719KCyclin-dependent kinase 22.7.11.220.491
2ds11CDCyclin-dependent kinase 22.7.11.220.489
2vthLZ2Cyclin-dependent kinase 22.7.11.220.489
3qzgX67Cyclin-dependent kinase 22.7.11.220.489
2vttLZDCyclin-dependent kinase 22.7.11.220.488
3r7yZ04Cyclin-dependent kinase 22.7.11.220.488
3rkb12ZCyclin-dependent kinase 22.7.11.220.488
1ke9LS5Cyclin-dependent kinase 22.7.11.220.485
4bgh3I6Cyclin-dependent kinase 22.7.11.220.485
3ral04ZCyclin-dependent kinase 22.7.11.220.484
4fkj11KCyclin-dependent kinase 22.7.11.220.484
1di8DTQCyclin-dependent kinase 22.7.11.220.483
1h1s4SPCyclin-dependent kinase 22.7.11.220.481
3ti1B49Cyclin-dependent kinase 22.7.11.220.481
1urwI1PCyclin-dependent kinase 22.7.11.220.480
3pj8404Cyclin-dependent kinase 22.7.11.220.479
3rm618ZCyclin-dependent kinase 22.7.11.220.478
3py0SU9Cyclin-dependent kinase 22.7.11.220.477
1ke7LS3Cyclin-dependent kinase 22.7.11.220.476
1h1r6CPCyclin-dependent kinase 22.7.11.220.474
3r9hZ67Cyclin-dependent kinase 22.7.11.220.474
3unk0BYCyclin-dependent kinase 22.7.11.220.472
1vjy460TGF-beta receptor type-12.7.11.300.471
2exmZIPCyclin-dependent kinase 22.7.11.220.471
2uzoC62Cyclin-dependent kinase 22.7.11.220.471
1w0xOLOCyclin-dependent kinase 22.7.11.220.470
2c6kDT2Cyclin-dependent kinase 22.7.11.220.470
3r71X86Cyclin-dependent kinase 22.7.11.220.468
1oguST8Cyclin-dependent kinase 22.7.11.220.465
2bhhRYUCyclin-dependent kinase 22.7.11.220.465
3rpo24ZCyclin-dependent kinase 22.7.11.220.463
1p2a5BNCyclin-dependent kinase 22.7.11.220.462
2a4lRRCCyclin-dependent kinase 22.7.11.220.462
4dgnLU2Casein kinase II subunit alpha2.7.11.10.462
4fklCK2Cyclin-dependent kinase 22.7.11.220.462
1y8yCT7Cyclin-dependent kinase 22.7.11.220.461
3rahO1ZCyclin-dependent kinase 22.7.11.220.461
3unj0BXCyclin-dependent kinase 22.7.11.220.461
1w8cN69Cyclin-dependent kinase 22.7.11.220.460
3qxoX65Cyclin-dependent kinase 22.7.11.220.460
1hckATPCyclin-dependent kinase 22.7.11.220.459
3qwjX6ACyclin-dependent kinase 22.7.11.220.459
4dgmAGICasein kinase II subunit alpha2.7.11.10.459
5cnoANPEpidermal growth factor receptor2.7.10.10.458
2c6lDT4Cyclin-dependent kinase 22.7.11.220.456
2pvnP63Casein kinase II subunit alpha2.7.11.10.456
3r8pZ46Cyclin-dependent kinase 22.7.11.220.456
3sheI85MAP kinase-activated protein kinase 32.7.11.10.456
2c5yMTWCyclin-dependent kinase 22.7.11.220.455
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.455
3sqq99ZCyclin-dependent kinase 22.7.11.220.455
4kd11QKCyclin-dependent kinase 22.7.11.220.455
2c6tDT5Cyclin-dependent kinase 22.7.11.220.454
2x1nX1NCyclin-dependent kinase 22.7.11.220.454
3rk507ZCyclin-dependent kinase 22.7.11.220.454
2iw94SPCyclin-dependent kinase 22.7.11.220.453
3nieANPMitogen-activated protein kinase/0.453
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.452
3r8vZ62Cyclin-dependent kinase 22.7.11.220.451
1b38ATPCyclin-dependent kinase 22.7.11.220.450
1qmzATPCyclin-dependent kinase 22.7.11.220.450
2b55D31Cyclin-dependent kinase 22.7.11.220.450
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.450
1ke8LS4Cyclin-dependent kinase 22.7.11.220.449
1v1k3FPCyclin-dependent kinase 22.7.11.220.449
1pxpCK8Cyclin-dependent kinase 22.7.11.220.448
1pyePM1Cyclin-dependent kinase 22.7.11.220.448
1vyzN5BCyclin-dependent kinase 22.7.11.220.448
2uzdC85Cyclin-dependent kinase 22.7.11.220.448
1oiuN76Cyclin-dependent kinase 22.7.11.220.447
1e1xNW1Cyclin-dependent kinase 22.7.11.220.446
4anmWULCasein kinase II subunit alpha2.7.11.10.446
2duv371Cyclin-dependent kinase 22.7.11.220.445
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.445
3qqkX02Cyclin-dependent kinase 22.7.11.220.445
1dayGNPCasein kinase II subunit alpha2.7.11.10.444
1h0w207Cyclin-dependent kinase 22.7.11.220.444
1oiyN41Cyclin-dependent kinase 22.7.11.220.444
3ddqRRCCyclin-dependent kinase 22.7.11.220.444
3rpy27ZCyclin-dependent kinase 22.7.11.220.444
4eok4SPCyclin-dependent kinase 22.7.11.220.444
4eon1ROCyclin-dependent kinase 22.7.11.220.444
1pkdUCNCyclin-dependent kinase 22.7.11.220.443
3nux3NVCyclin-dependent kinase 62.7.11.220.442
2uzbC75Cyclin-dependent kinase 22.7.11.220.440
3be9P04Casein kinase II subunit alpha2.7.11.10.440
4aua4AUCyclin-dependent kinase 62.7.11.220.440