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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fklCK2Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4fklCK2Cyclin-dependent kinase 22.7.11.221.000
1w8cN69Cyclin-dependent kinase 22.7.11.220.644
2a0cCK9Cyclin-dependent kinase 22.7.11.220.552
3r83Z14Cyclin-dependent kinase 22.7.11.220.547
3lfqA28Cyclin-dependent kinase 22.7.11.220.539
3r8vZ62Cyclin-dependent kinase 22.7.11.220.523
2r3jSCJCyclin-dependent kinase 22.7.11.220.520
2r3iSCFCyclin-dependent kinase 22.7.11.220.515
2exmZIPCyclin-dependent kinase 22.7.11.220.513
1oirHDYCyclin-dependent kinase 22.7.11.220.510
1oitHDTCyclin-dependent kinase 22.7.11.220.509
4fki09KCyclin-dependent kinase 22.7.11.220.502
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.500
3r7yZ04Cyclin-dependent kinase 22.7.11.220.499
3rahO1ZCyclin-dependent kinase 22.7.11.220.498
3r1yX76Cyclin-dependent kinase 22.7.11.220.496
1b38ATPCyclin-dependent kinase 22.7.11.220.490
2c6kDT2Cyclin-dependent kinase 22.7.11.220.490
2a4lRRCCyclin-dependent kinase 22.7.11.220.489
4ek610KCyclin-dependent kinase 22.7.11.220.484
2vtsLZCCyclin-dependent kinase 22.7.11.220.482
4ek816KCyclin-dependent kinase 22.7.11.220.481
4fkt48KCyclin-dependent kinase 22.7.11.220.480
3qqlX03Cyclin-dependent kinase 22.7.11.220.479
2c6o4SPCyclin-dependent kinase 22.7.11.220.478
2c6lDT4Cyclin-dependent kinase 22.7.11.220.475
2btrU73Cyclin-dependent kinase 22.7.11.220.469
3lfnA27Cyclin-dependent kinase 22.7.11.220.469
1y8yCT7Cyclin-dependent kinase 22.7.11.220.466
4fkg4CKCyclin-dependent kinase 22.7.11.220.464
1ykr628Cyclin-dependent kinase 22.7.11.220.463
4kd11QKCyclin-dependent kinase 22.7.11.220.463
3le62BZCyclin-dependent kinase 22.7.11.220.459
1pxjCK2Cyclin-dependent kinase 22.7.11.220.457
2r3fSC8Cyclin-dependent kinase 22.7.11.220.457
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.455
3qwjX6ACyclin-dependent kinase 22.7.11.220.454
2c6iDT1Cyclin-dependent kinase 22.7.11.220.453
2r3q5SCCyclin-dependent kinase 22.7.11.220.453
3r8lZ30Cyclin-dependent kinase 22.7.11.220.452
2b53D23Cyclin-dependent kinase 22.7.11.220.451
2r3r6SCCyclin-dependent kinase 22.7.11.220.447
4fkpLS5Cyclin-dependent kinase 22.7.11.220.447
3r7uX96Cyclin-dependent kinase 22.7.11.220.446
1pxmCK5Cyclin-dependent kinase 22.7.11.220.445
3r9nZ68Cyclin-dependent kinase 22.7.11.220.445
1pxoCK7Cyclin-dependent kinase 22.7.11.220.440