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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fki09KCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4fki09KCyclin-dependent kinase 22.7.11.221.000
3lfnA27Cyclin-dependent kinase 22.7.11.220.654
3lfqA28Cyclin-dependent kinase 22.7.11.220.599
4ek610KCyclin-dependent kinase 22.7.11.220.588
3r1yX76Cyclin-dependent kinase 22.7.11.220.584
2a0cCK9Cyclin-dependent kinase 22.7.11.220.581
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.575
3lfsA07Cyclin-dependent kinase 22.7.11.220.570
3s2pPMUCyclin-dependent kinase 22.7.11.220.570
2btrU73Cyclin-dependent kinase 22.7.11.220.565
3r7vZ02Cyclin-dependent kinase 22.7.11.220.561
1oitHDTCyclin-dependent kinase 22.7.11.220.560
3qxoX65Cyclin-dependent kinase 22.7.11.220.558
4lyn1YGCyclin-dependent kinase 22.7.11.220.557
4fkpLS5Cyclin-dependent kinase 22.7.11.220.555
3r8lZ30Cyclin-dependent kinase 22.7.11.220.551
4fkj11KCyclin-dependent kinase 22.7.11.220.551
1w8cN69Cyclin-dependent kinase 22.7.11.220.550
1pxoCK7Cyclin-dependent kinase 22.7.11.220.548
3qzgX67Cyclin-dependent kinase 22.7.11.220.548
1ke5LS1Cyclin-dependent kinase 22.7.11.220.543
4fkq42KCyclin-dependent kinase 22.7.11.220.542
3qwjX6ACyclin-dependent kinase 22.7.11.220.541
4fkt48KCyclin-dependent kinase 22.7.11.220.541
4fklCK2Cyclin-dependent kinase 22.7.11.220.540
1pxmCK5Cyclin-dependent kinase 22.7.11.220.539
1w0xOLOCyclin-dependent kinase 22.7.11.220.539
2c6o4SPCyclin-dependent kinase 22.7.11.220.537
3rpo24ZCyclin-dependent kinase 22.7.11.220.537
3r8vZ62Cyclin-dependent kinase 22.7.11.220.534
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.533
3r83Z14Cyclin-dependent kinase 22.7.11.220.531
2btsU32Cyclin-dependent kinase 22.7.11.220.530
3pxyJWSCyclin-dependent kinase 22.7.11.220.530
3r7yZ04Cyclin-dependent kinase 22.7.11.220.530
3rm618ZCyclin-dependent kinase 22.7.11.220.529
1hckATPCyclin-dependent kinase 22.7.11.220.528
3r7uX96Cyclin-dependent kinase 22.7.11.220.528
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.523
1di8DTQCyclin-dependent kinase 22.7.11.220.522
2r3jSCJCyclin-dependent kinase 22.7.11.220.521
3qu0X40Cyclin-dependent kinase 22.7.11.220.521
1v1k3FPCyclin-dependent kinase 22.7.11.220.519
3rm719ZCyclin-dependent kinase 22.7.11.220.518
4fkg4CKCyclin-dependent kinase 22.7.11.220.518
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.517
3rni21ZCyclin-dependent kinase 22.7.11.220.517
1b38ATPCyclin-dependent kinase 22.7.11.220.516
2r3lSCWCyclin-dependent kinase 22.7.11.220.516
3iggEFQCyclin-dependent kinase 22.7.11.220.515
2duv371Cyclin-dependent kinase 22.7.11.220.514
2vthLZ2Cyclin-dependent kinase 22.7.11.220.514
1gii1PUCyclin-dependent kinase 22.7.11.220.513
3qqlX03Cyclin-dependent kinase 22.7.11.220.513
2uzoC62Cyclin-dependent kinase 22.7.11.220.512
4ek816KCyclin-dependent kinase 22.7.11.220.512
4ez30S0Cyclin-dependent kinase 22.7.11.220.512
1ke6LS2Cyclin-dependent kinase 22.7.11.220.511
1oirHDYCyclin-dependent kinase 22.7.11.220.510
1ykr628Cyclin-dependent kinase 22.7.11.220.510
2b52D42Cyclin-dependent kinase 22.7.11.220.509
3roy22ZCyclin-dependent kinase 22.7.11.220.509
2a4lRRCCyclin-dependent kinase 22.7.11.220.506
2xmyCDKCyclin-dependent kinase 22.7.11.220.505
3r6xX84Cyclin-dependent kinase 22.7.11.220.504
3rk708ZCyclin-dependent kinase 22.7.11.220.503
2w06FRVCyclin-dependent kinase 22.7.11.220.502
2r64740Cyclin-dependent kinase 22.7.11.220.499
3rk909ZCyclin-dependent kinase 22.7.11.220.499
4acm7YGCyclin-dependent kinase 22.7.11.220.499
1gih1PUCyclin-dependent kinase 22.7.11.220.498
1g5sI17Cyclin-dependent kinase 22.7.11.220.496
3sqq99ZCyclin-dependent kinase 22.7.11.220.495
3qzhX69Cyclin-dependent kinase 22.7.11.220.494
2r3mSCXCyclin-dependent kinase 22.7.11.220.493
1ke7LS3Cyclin-dependent kinase 22.7.11.220.492
3ezvEZVCyclin-dependent kinase 22.7.11.220.492
2w1hL0FCyclin-dependent kinase 22.7.11.220.491
3qqhX0ACyclin-dependent kinase 22.7.11.220.490
3sw418KCyclin-dependent kinase 22.7.11.220.489
3s1h56ZCyclin-dependent kinase 22.7.11.220.488
1b39ATPCyclin-dependent kinase 22.7.11.220.486
1e1xNW1Cyclin-dependent kinase 22.7.11.220.486
3r1qX75Cyclin-dependent kinase 22.7.11.220.486
4fkv61KCyclin-dependent kinase 22.7.11.220.486
3r73X87Cyclin-dependent kinase 22.7.11.220.485
4kd11QKCyclin-dependent kinase 22.7.11.220.485
1pxlCK4Cyclin-dependent kinase 22.7.11.220.484
1y91CT9Cyclin-dependent kinase 22.7.11.220.484
2b53D23Cyclin-dependent kinase 22.7.11.220.484
3ddqRRCCyclin-dependent kinase 22.7.11.220.484
3rpv26ZCyclin-dependent kinase 22.7.11.220.484
2c5yMTWCyclin-dependent kinase 22.7.11.220.483
1oguST8Cyclin-dependent kinase 22.7.11.220.482
1vyzN5BCyclin-dependent kinase 22.7.11.220.482
1y8yCT7Cyclin-dependent kinase 22.7.11.220.482
4fks46KCyclin-dependent kinase 22.7.11.220.482
1h0w207Cyclin-dependent kinase 22.7.11.220.481
2exmZIPCyclin-dependent kinase 22.7.11.220.481
4nj32KDCyclin-dependent kinase 22.7.11.220.481
2r3p3SCCyclin-dependent kinase 22.7.11.220.480
1h1r6CPCyclin-dependent kinase 22.7.11.220.479
1h1s4SPCyclin-dependent kinase 22.7.11.220.479
1aq1STUCyclin-dependent kinase 22.7.11.220.478
2r3iSCFCyclin-dependent kinase 22.7.11.220.478
3fz1B98Cyclin-dependent kinase 22.7.11.220.478
3qtuX44Cyclin-dependent kinase 22.7.11.220.478
3r7eX88Cyclin-dependent kinase 22.7.11.220.478
3qx2X63Cyclin-dependent kinase 22.7.11.220.477
3rjc06ZCyclin-dependent kinase 22.7.11.220.477
3rk507ZCyclin-dependent kinase 22.7.11.220.477
3unk0BYCyclin-dependent kinase 22.7.11.220.477
4bgh3I6Cyclin-dependent kinase 22.7.11.220.477
3ddpRC8Cyclin-dependent kinase 22.7.11.220.476
3qqkX02Cyclin-dependent kinase 22.7.11.220.476
3r9dX6BCyclin-dependent kinase 22.7.11.220.475
2b55D31Cyclin-dependent kinase 22.7.11.220.474
3r71X86Cyclin-dependent kinase 22.7.11.220.474
1ckpPVBCyclin-dependent kinase 22.7.11.220.473
3rahO1ZCyclin-dependent kinase 22.7.11.220.473
3rak03ZCyclin-dependent kinase 22.7.11.220.473
3rkb12ZCyclin-dependent kinase 22.7.11.220.473
4eon1ROCyclin-dependent kinase 22.7.11.220.473
1urwI1PCyclin-dependent kinase 22.7.11.220.472
2uznC96Cyclin-dependent kinase 22.7.11.220.472
2r3kSCQCyclin-dependent kinase 22.7.11.220.470
3r7iX9ICyclin-dependent kinase 22.7.11.220.470
1p2a5BNCyclin-dependent kinase 22.7.11.220.469
3qtzX42Cyclin-dependent kinase 22.7.11.220.469
3r1sX73Cyclin-dependent kinase 22.7.11.220.469
2iw94SPCyclin-dependent kinase 22.7.11.220.468
3ral04ZCyclin-dependent kinase 22.7.11.220.467
4fkr45KCyclin-dependent kinase 22.7.11.220.467
3r28XA0Cyclin-dependent kinase 22.7.11.220.466
3s0o50ZCyclin-dependent kinase 22.7.11.220.466
2vttLZDCyclin-dependent kinase 22.7.11.220.465
2vu3LZECyclin-dependent kinase 22.7.11.220.464
3ezrEZRCyclin-dependent kinase 22.7.11.220.464
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.463
3raiX85Cyclin-dependent kinase 22.7.11.220.463
3rmf20ZCyclin-dependent kinase 22.7.11.220.463
3sw719KCyclin-dependent kinase 22.7.11.220.462
1ke9LS5Cyclin-dependent kinase 22.7.11.220.461
2c6kDT2Cyclin-dependent kinase 22.7.11.220.461
3r8pZ46Cyclin-dependent kinase 22.7.11.220.461
2vtrLZBCyclin-dependent kinase 22.7.11.220.459
2vv9IM9Cyclin-dependent kinase 22.7.11.220.459
4bcoT6QCyclin-dependent kinase 22.7.11.220.457
1oiqHDUCyclin-dependent kinase 22.7.11.220.456
2c6lDT4Cyclin-dependent kinase 22.7.11.220.456
3ig7EFPCyclin-dependent kinase 22.7.11.220.456
3qqgX06Cyclin-dependent kinase 22.7.11.220.456
3qziX72Cyclin-dependent kinase 22.7.11.220.456
4bcmT7ZCyclin-dependent kinase 22.7.11.220.456
2c6iDT1Cyclin-dependent kinase 22.7.11.220.455
3qruX19Cyclin-dependent kinase 22.7.11.220.455
3qxpX64Cyclin-dependent kinase 22.7.11.220.455
1r78FMDCyclin-dependent kinase 22.7.11.220.454
4erwSTUCyclin-dependent kinase 22.7.11.220.454
2fvdLIACyclin-dependent kinase 22.7.11.220.453
1oi9N20Cyclin-dependent kinase 22.7.11.220.452
1pxpCK8Cyclin-dependent kinase 22.7.11.220.452
3tiz3TICyclin-dependent kinase 22.7.11.220.452
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.452
3pj8404Cyclin-dependent kinase 22.7.11.220.451
2r3gSC9Cyclin-dependent kinase 22.7.11.220.450
3qwkX62Cyclin-dependent kinase 22.7.11.220.448
2r3r6SCCyclin-dependent kinase 22.7.11.220.447
1ke8LS4Cyclin-dependent kinase 22.7.11.220.446
2iw84SPCyclin-dependent kinase 22.7.11.220.446
2vtsLZCCyclin-dependent kinase 22.7.11.220.446
3qtrX36Cyclin-dependent kinase 22.7.11.220.446
3qqfX07Cyclin-dependent kinase 22.7.11.220.445
2bhhRYUCyclin-dependent kinase 22.7.11.220.444
1vyw292Cyclin-dependent kinase 22.7.11.220.443
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.443
3sheI85MAP kinase-activated protein kinase 32.7.11.10.443
3wblPDYCyclin-dependent kinase 22.7.11.220.443
1pxkCK3Cyclin-dependent kinase 22.7.11.220.442
1pyePM1Cyclin-dependent kinase 22.7.11.220.442
3nynSGVG protein-coupled receptor kinase 62.7.11.160.442
3qtxX43Cyclin-dependent kinase 22.7.11.220.442
3ti1B49Cyclin-dependent kinase 22.7.11.220.442
4fko20KCyclin-dependent kinase 22.7.11.220.441
3nux3NVCyclin-dependent kinase 62.7.11.220.440
3qx4X4BCyclin-dependent kinase 22.7.11.220.440
5aniES4Cyclin-dependent kinase 22.7.11.220.440