sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4fhh | 0U3 | Vitamin D3 receptor A |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 1.000 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.783 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.774 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.747 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.740 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.738 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.727 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.713 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.707 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.700 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.699 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.695 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.681 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.675 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.674 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.672 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.669 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.666 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.664 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.662 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.660 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.656 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.654 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.647 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.645 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.644 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.644 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.643 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.642 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.642 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.641 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.640 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.639 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.639 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.639 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.638 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.637 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.637 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.637 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.636 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.636 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.635 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.635 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.634 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.633 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.633 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.630 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.630 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.629 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.628 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.626 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.626 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.625 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.623 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.619 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.615 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.615 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.613 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.609 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.609 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.608 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.605 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.599 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.597 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.596 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.596 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.581 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.577 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.569 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.491 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.489 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.481 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.470 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.465 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.463 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.460 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.455 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.454 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.454 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.453 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.452 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.447 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3nf7 | CIW | Gag-Pol polyprotein | / | 0.444 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.443 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.443 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 4l8u | 9AZ | Serum albumin | / | 0.443 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.443 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.441 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.441 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.440 |