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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.17

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.171.000
5av2KMPDeath-associated protein kinase 12.7.11.10.491
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.479
5av3KMPDeath-associated protein kinase 12.7.11.10.470
1jklANPDeath-associated protein kinase 12.7.11.10.456
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.454
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.453
3lltANPProtein serine/threonine kinase-1/0.450
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.445
4j95ACPFibroblast growth factor receptor 2/0.445
3c4xATPRhodopsin kinase/0.443
4ysjADPCalmodulin-like domain protein kinase/0.442