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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fam0SZAldo-keto reductase family 1 member C3

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4fam0SZAldo-keto reductase family 1 member C3/1.000
4dbuBT9Aldo-keto reductase family 1 member C3/0.512
1zq5E04Aldo-keto reductase family 1 member C3/0.466
1ry8RUTAldo-keto reductase family 1 member C3/0.464
4dbs0HVAldo-keto reductase family 1 member C3/0.458
2f3815MAldo-keto reductase family 1 member C3/0.456
4dbw511Aldo-keto reductase family 1 member C3/0.446