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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4f7j0SUCyclin-dependent kinase 82.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4f7j0SUCyclin-dependent kinase 82.7.11.221.000
4f7n0SVCyclin-dependent kinase 82.7.11.220.637
4f6s0SQCyclin-dependent kinase 82.7.11.220.581
5hidB1ESerine/threonine-protein kinase B-raf2.7.11.10.553
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.541
1w82L10Mitogen-activated protein kinase 14/0.537
3hv4L51Mitogen-activated protein kinase 14/0.531
2yiwYIWMitogen-activated protein kinase 14/0.528
3hv71AUMitogen-activated protein kinase 14/0.528
3nnwEDDMitogen-activated protein kinase 14/0.527
3npcB96Mitogen-activated protein kinase 92.7.11.240.522
1kv1BMUMitogen-activated protein kinase 14/0.521
3nnxEDDMitogen-activated protein kinase 14/0.517
3ugc046Tyrosine-protein kinase JAK2/0.514
3lfbZ87Mitogen-activated protein kinase 14/0.512
3vhe42QVascular endothelial growth factor receptor 22.7.10.10.512
3d83GK6Mitogen-activated protein kinase 14/0.505
3p5kP5KMitogen-activated protein kinase 14/0.505
1wbvLI3Mitogen-activated protein kinase 14/0.499
3p7aP7AMitogen-activated protein kinase 14/0.499
5cvhADPCasein kinase II subunit alpha2.7.11.10.496
3o8uBMUMitogen-activated protein kinase 14/0.494
3wzeBAXVascular endothelial growth factor receptor 22.7.10.10.494
3nnuEDBMitogen-activated protein kinase 14/0.491
4hw764MMacrophage colony-stimulating factor 1 receptor2.7.10.10.491
1wbnL09Mitogen-activated protein kinase 14/0.490
1wbsLI2Mitogen-activated protein kinase 14/0.490
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.490
4c02TAKActivin receptor type-12.7.11.300.488
1wbtWBTMitogen-activated protein kinase 14/0.487
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.487
3hv5R24Mitogen-activated protein kinase 14/0.487
3hv6R39Mitogen-activated protein kinase 14/0.486
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.485
4l8mF46Mitogen-activated protein kinase 14/0.485
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.482
3rps4B0Casein kinase II subunit alpha2.7.11.10.482
4k8aK8AFocal adhesion kinase 12.7.10.20.482
1b39ATPCyclin-dependent kinase 22.7.11.220.481
2cduADPNADH oxidase/0.481
2yisYISMitogen-activated protein kinase 14/0.481
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.481
3p7cP7CMitogen-activated protein kinase 14/0.481
4aa0AA0Mitogen-activated protein kinase 14/0.481
4ccbOFGALK tyrosine kinase receptor2.7.10.10.481
1ir3ANPInsulin receptor2.7.10.10.479
3uvr06FMitogen-activated protein kinase 14/0.479
4i4e1BQFocal adhesion kinase 12.7.10.20.479
4mwhATPCasein kinase II subunit alpha2.7.11.10.479
1g69TZPThiamine-phosphate synthase/0.478
2qqfA1RNAD-dependent protein deacetylase HST23.5.10.478
3lffZ83Mitogen-activated protein kinase 14/0.477
1fq1ATPCyclin-dependent kinase 22.7.11.220.476
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.476
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.476
3p7bP7BMitogen-activated protein kinase 14/0.476
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.476
2xauADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP433.6.4.130.475
3gcvSS6Mitogen-activated protein kinase 14/0.475
1lp4ANPCasein kinase II subunit alpha2.7.11.10.474
2plmSIB5-methylthioadenosine/S-adenosylhomocysteine deaminase3.5.4.280.474
3gi3B10Mitogen-activated protein kinase 14/0.474
2xuuADPDeath-associated protein kinase 12.7.11.10.473
3gcuR48Mitogen-activated protein kinase 14/0.473
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.473
4i22IREEpidermal growth factor receptor2.7.10.10.473
1i44ACPInsulin receptor2.7.10.10.472
4r7iSTIMacrophage colony-stimulating factor 1 receptor2.7.10.10.472
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.472
1lb9DNQGlutamate receptor 2/0.471
1xp9AIJEstrogen receptor/0.471
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.471
2xs0ANPMitogen-activated protein kinase 82.7.11.240.471
3q2mCKISpectinomycin phosphotransferase/0.471
3vs3VSETyrosine-protein kinase HCK2.7.10.20.471
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.471
4k9yK9YFocal adhesion kinase 12.7.10.20.471
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.470
4ehv0SJMitogen-activated protein kinase 14/0.470
4pxmESTEstrogen receptor/0.470
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.469
4ds8A8SAbscisic acid receptor PYL3/0.469
1qknRALEstrogen receptor beta/0.468
2z7lS91Mitogen-activated protein kinase 12.7.11.240.468
3p78P78Mitogen-activated protein kinase 14/0.468
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.467
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.466
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4ic7ANPMitogen-activated protein kinase 72.7.11.240.466
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.466
1o6kANPRAC-beta serine/threonine-protein kinase2.7.11.10.465
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.465
2hl2SSAThreonine--tRNA ligase6.1.1.30.465
2hz0GINTyrosine-protein kinase ABL12.7.10.20.465
2qgtEEDEstrogen receptor/0.465
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.465
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.465
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.465
1jdbADPCarbamoyl-phosphate synthase large chain/0.464
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.464
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.464
3w16P9JAurora kinase A2.7.11.10.464
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.464
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.464
1kv2B96Mitogen-activated protein kinase 14/0.463
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.463
3plsANPMacrophage-stimulating protein receptor2.7.10.10.463
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.463
4hh0FMNAppA protein/0.463
4iw8KN3Estrogen receptor/0.463
1h9zRWFSerum albumin/0.462
1yimCM4Estrogen receptor/0.462
1ykdCMPAdenylate cyclase/0.462
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.462
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.462
4f9wLM4Mitogen-activated protein kinase 14/0.462
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.462
4jrnANPRhoptry kinase family protein/0.462
4ng2OHNTranscriptional activator protein LasR/0.462
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.462
1yqj6NPMitogen-activated protein kinase 14/0.461
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.461
4c4g7RODual specificity protein kinase TTK2.7.12.10.461
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.461
1c72EPYGlutathione S-transferase 22.5.1.180.460
1zhwHC2Oxysterol-binding protein homolog 4/0.460
2c4g514Cyclin-dependent kinase 22.7.11.220.460
2j2pSC2Ficolin-2/0.460
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.460
4eh90OQMitogen-activated protein kinase 14/0.460
4r38RBFBlue-light-activated histidine kinase 22.7.13.30.460
5auwQUEDeath-associated protein kinase 12.7.11.10.460
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.459
3tljSAHUncharacterized protein/0.459
4b8lA0PAurora kinase B-A2.7.11.10.459
4fi1ATPCasein kinase II subunit alpha2.7.11.10.459
1h0w207Cyclin-dependent kinase 22.7.11.220.458
1yp3ATPGlucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic2.7.7.270.458
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.458
2wotZZGTGF-beta receptor type-12.7.11.300.458
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.458
3poz03PEpidermal growth factor receptor2.7.10.10.458
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
4bcoT6QCyclin-dependent kinase 22.7.11.220.458
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.458
4xr9TMPCalS8/0.458
1finATPCyclin-dependent kinase 22.7.11.220.457
2etm7PYFocal adhesion kinase 12.7.10.20.457
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.457
3eyhIZATyrosine-protein kinase JAK1/0.457
3f5uANPDeath-associated protein kinase 12.7.11.10.457
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
4fuxE75Mitogen-activated protein kinase 12.7.11.240.457
4j26ESTEstrogen receptor beta/0.457
4k6i9RARetinoic acid receptor RXR-alpha/0.457
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
1y9r1CAMineralocorticoid receptor/0.456
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
4anmWULCasein kinase II subunit alpha2.7.11.10.456
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.456
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.455
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3flsFLSMitogen-activated protein kinase 14/0.455
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.455
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.455
4bcmT7ZCyclin-dependent kinase 22.7.11.220.455
4c4h7RODual specificity protein kinase TTK2.7.12.10.455
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.455
4lgaA2OAbscisic acid receptor PYL2/0.455
4nx6FOLDihydrofolate reductase1.5.1.30.455
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.454
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.454
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.454
2qo7ANPEphrin type-A receptor 32.7.10.10.454
2w4kADPDeath-associated protein kinase 12.7.11.10.454
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.454
4xhgADPUncharacterized protein/0.454
4ysjADPCalmodulin-like domain protein kinase/0.454
1ictT44Transthyretin/0.453
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.453
2itpAEEEpidermal growth factor receptor2.7.10.10.453
3e9319BMitogen-activated protein kinase 14/0.453
3nj0PYVAbscisic acid receptor PYL2/0.453
3t7vSAM3-methylornithine synthase/0.453
3zdu38RCyclin-dependent kinase-like 32.7.11.220.453
4b99R4LMitogen-activated protein kinase 72.7.11.240.453
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.453
4meo25VBromodomain-containing protein 4/0.453
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.453
4yswFADXanthine dehydrogenase/oxidase/0.453
5dxgESTEstrogen receptor/0.453
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
1gx1CDP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.452
1jstATPCyclin-dependent kinase 22.7.11.220.452
2duv371Cyclin-dependent kinase 22.7.11.220.452
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.452
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.452
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.452
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.452
3sw1FMNSensory box protein/0.452
4asdBAXVascular endothelial growth factor receptor 22.7.10.10.452
4bzqADPBifunctional enzyme CysN/CysC2.7.1.250.452
4h3pANPMitogen-activated protein kinase 12.7.11.240.452
4p6wMOFGlucocorticoid receptor/0.452
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.452
4y95746Tyrosine-protein kinase/0.452
5auxKMPDeath-associated protein kinase 12.7.11.10.452
1d2sDHTSex hormone-binding globulin/0.451
1hk2T44Serum albumin/0.451
1w84L12Mitogen-activated protein kinase 14/0.451
1wvxBD4Death-associated protein kinase 12.7.11.10.451
1x7b041Estrogen receptor beta/0.451
2az3CDPNucleoside diphosphate kinase/0.451
2ghmLICMitogen-activated protein kinase 14/0.451
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.451
2oyfIACBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.451
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.451
2rgxAP5Adenylate kinase/0.451
3orlAGSSerine/threonine protein kinase/0.451
4d58BI9Focal adhesion kinase 12.7.10.20.451
4fkj11KCyclin-dependent kinase 22.7.11.220.451
4iu71GMEstrogen receptor/0.451
4yklGMPAprataxin-like protein30.451
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.450
1opbRETRetinol-binding protein 2/0.450
1pp9SMACytochrome b/0.450
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.450
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.450
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.450
3ezrEZRCyclin-dependent kinase 22.7.11.220.450
3gxfIFMGlucosylceramidase3.2.1.450.450
3jpuTY4Transcriptional activator protein LasR/0.450
3w0aDS5Vitamin D3 receptor/0.450
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.450
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4e37NDPCatalase1.11.1.60.450
4uxxACPDiacylglycerol kinase2.7.1.1070.450
4xbaGMPAprataxin-like protein30.450
4xlvACPInsulin receptor2.7.10.10.450
5awmANPStress-activated protein kinase JNK2.7.11.240.450
5h8tRTLRetinol-binding protein 1/0.450
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.449
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.449
2erzHFScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2y9qANPMitogen-activated protein kinase 12.7.11.240.449
3bu5ATPInsulin receptor2.7.10.10.449
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.449
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.449
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.449
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.449
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.449
4n6hEJ4Delta-type opioid receptor/0.449
4utdACPAurora kinase A2.7.11.10.449
5ifyTRHGlucose-1-phosphate thymidylyltransferase/0.449
1eetBFUGag-Pol polyprotein2.7.7.490.448
1h0vUN4Cyclin-dependent kinase 22.7.11.220.448
1hk1T44Serum albumin/0.448
1jkkANPDeath-associated protein kinase 12.7.11.10.448
1lhvNOGSex hormone-binding globulin/0.448
1nhwTCCEnoyl-ACP reductase/0.448
2hk51BMTyrosine-protein kinase HCK2.7.10.20.448
2x9fX9FEphrin type-B receptor 42.7.10.10.448
2xp2VGHALK tyrosine kinase receptor2.7.10.10.448
2xvu9DNSerum albumin/0.448
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
3ormAGSSerine/threonine protein kinase/0.448
3qx4X4BCyclin-dependent kinase 22.7.11.220.448
3tm5SFGUncharacterized protein/0.448
3w33W19Epidermal growth factor receptor2.7.10.10.448
3ztxZTXAurora kinase B-A2.7.11.10.448
4b1vATPActin, alpha skeletal muscle/0.448
4eji0QACytochrome P450 2A131.14.14.10.448
4okx198Androgen receptor/0.448
5hi2BAXSerine/threonine-protein kinase B-raf2.7.11.10.448
1pmv537Mitogen-activated protein kinase 102.7.11.240.447
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.447
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.447
2cdaNAPGlucose 1-dehydrogenase/0.447
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.447
2vwu7X1Ephrin type-B receptor 42.7.10.10.447
2xngA0HAurora kinase A2.7.11.10.447
2zlcVDXVitamin D3 receptor/0.447
3dd125DGlycogen phosphorylase, liver form2.4.1.10.447
3qqgX06Cyclin-dependent kinase 22.7.11.220.447
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.447
3w2sW2REpidermal growth factor receptor2.7.10.10.447
4i5i4I5NAD-dependent protein deacetylase sirtuin-13.5.10.447
4izy1J2Mitogen-activated protein kinase 82.7.11.240.447
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.447
5c8rUPGHisto-blood group ABO system transferase/0.447
5i2hAGIO-methyltransferase family 2/0.447
1j39UPGDNA beta-glucosyltransferase/0.446
1q4xG24Thyroid hormone receptor beta/0.446
1tezHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1v0oINRCell division control protein 2 homolog2.7.11.220.446
1x7e244Estrogen receptor/0.446
1zaf789Estrogen receptor beta/0.446
2c5yMTWCyclin-dependent kinase 22.7.11.220.446
2ckeIQUDeath-associated protein kinase 2/0.446
2iyiFMNAppA, antirepressor of ppsR, sensor of blue light/0.446
2ojg19AMitogen-activated protein kinase 12.7.11.240.446
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3a62STURibosomal protein S6 kinase beta-12.7.11.10.446
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.446
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.446
3kq7KQ7Mitogen-activated protein kinase 14/0.446
3lxkMI1Tyrosine-protein kinase JAK32.7.10.20.446
3rgfBAXCyclin-dependent kinase 82.7.11.220.446
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4cd0AWJALK tyrosine kinase receptor2.7.10.10.446
4hj3FMNLOV protein/0.446
4s33ANPMitogen-activated protein kinase 12.7.11.240.446
5dt0SKEAurora kinase A2.7.11.10.446
1b38ATPCyclin-dependent kinase 22.7.11.220.445
1enzNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
1xjgDTPVitamin B12-dependent ribonucleotide reductase/0.445
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.445
1yye196Estrogen receptor beta/0.445
2bujSTUSerine/threonine-protein kinase 16/0.445
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.445
2hog710Serine/threonine-protein kinase Chk12.7.11.10.445
2itqITQEpidermal growth factor receptor2.7.10.10.445
2othNIMBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.445
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.445
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.445
3rm719ZCyclin-dependent kinase 22.7.11.220.445
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.445
3tnwF18Cyclin-dependent kinase 22.7.11.220.445
3udzADPInositol-pentakisphosphate 2-kinase2.7.1.1580.445
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.445
4at2ASDPossible succinate dehydrogenase/0.445
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4fmqANPMitogen-activated protein kinase 12.7.11.240.445
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.445
4ho8UPGGlucose-1-phosphate thymidylyltransferase/0.445
4iv21GREstrogen receptor/0.445
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4k33ACPFibroblast growth factor receptor 32.7.10.10.445
4men25KBromodomain-containing protein 4/0.445
4n57ADPAPH(2'')-Id/0.445
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.445
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.445
4xybNDPFormate dehydrogenase/0.445
5dx3ESTEstrogen receptor/0.445
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1pxlCK4Cyclin-dependent kinase 22.7.11.220.444
1qiwDPDCalmodulin/0.444
1wvySTUDeath-associated protein kinase 12.7.11.10.444
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.444
2vd5BI8Myotonin-protein kinase2.7.11.10.444
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.444
2zybKSLTyrosine-protein kinase Lck2.7.10.20.444
3f4bTCLEnoyl-acyl carrier protein reductase/0.444
3mpaSB2Mitogen-activated protein kinase 14/0.444
3ujlA8SAbscisic acid receptor PYL2/0.444
3zvuA8SAbscisic acid receptor PYR1/0.444
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.444
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.444
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.444
4eor4SPCyclin-dependent kinase 22.7.11.220.444
4fz70VHTyrosine-protein kinase SYK2.7.10.20.444
4jl5ADPAdenylate kinase/0.444
4o1pANPRibonuclease L/0.444
5e8wSTUTGF-beta receptor type-12.7.11.300.444
1qmfKEFPenicillin-binding protein 2x/0.443
1txiTX5Vitamin D3 receptor/0.443
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.443
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.443
2izrBRKCasein kinase I isoform gamma-32.7.11.10.443
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.443
2p4yC03Peroxisome proliferator-activated receptor gamma/0.443
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.443
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.443
3hk1B64Fatty acid-binding protein, adipocyte/0.443
3k5uPFQAurora kinase A2.7.11.10.443
3l05SN0N-acetylornithine carbamoyltransferase2.1.3.90.443
3nga3NGCasein kinase II subunit alpha2.7.11.10.443
3ryeUNRFarnesyl pyrophosphate synthase2.5.1.100.443
3w0c6DSVitamin D3 receptor/0.443
4fnzNZFALK tyrosine kinase receptor2.7.10.10.443
4gncASORegucalcin3.1.1.170.443
4hyu1BKMitogen-activated protein kinase 82.7.11.240.443
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.443
1g50ESTEstrogen receptor/0.442
1it7GUNtRNA-guanine(15) transglycosylase2.4.2.480.442
1klkPMDDihydrofolate reductase1.5.1.30.442
1naxIH5Thyroid hormone receptor beta/0.442
1oiuN76Cyclin-dependent kinase 22.7.11.220.442
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.442
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.442
2jf9OHTEstrogen receptor/0.442
2od7A1RNAD-dependent protein deacetylase HST23.5.10.442
2pmoHMDProtein kinase 7/0.442
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.442
3emg685Tyrosine-protein kinase SYK2.7.10.20.442
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.442
3u0zCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1/0.442
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4bcqTJFCyclin-dependent kinase 22.7.11.220.442
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.442
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.442
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.442
4gk3L87Ephrin type-A receptor 32.7.10.10.442
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.442
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.442
1hckATPCyclin-dependent kinase 22.7.11.220.441
1ijjATPActin, alpha skeletal muscle/0.441
1w4xFADPhenylacetone monooxygenase1.14.13.920.441
1xp1AIHEstrogen receptor/0.441
2itnANPEpidermal growth factor receptor2.7.10.10.441
2ituITQEpidermal growth factor receptor2.7.10.10.441
2j7yE3OEstrogen receptor beta/0.441
2oaxSNLMineralocorticoid receptor/0.441
2pin4HYThyroid hormone receptor beta/0.441
2pywADPMethylthioribose kinase2.7.1.1000.441
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.441
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.441
3at4CCKCasein kinase II subunit alpha2.7.11.10.441
3igoANPCalmodulin-domain protein kinase 1, putative/0.441
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3miaANPCyclin-dependent kinase 92.7.11.220.441
3nszANPCasein kinase II subunit alpha2.7.11.10.441
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.441
3ttiKBIMitogen-activated protein kinase 102.7.11.240.441
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.441
4cvbPQQAlcohol dehydrogenase/0.441
4dh5ADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4fob0USALK tyrosine kinase receptor2.7.10.10.441
4g0k0VSGlutathionyl-hydroquinone reductase YqjG1.80.441
4gapFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
4iarERM5-hydroxytryptamine receptor 1B/0.441
4ju31O1Genome polyprotein2.7.7.480.441
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.441
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.441
4qknJMSAlpha-ketoglutarate-dependent dioxygenase FTO/0.441
1dyrTOPDihydrofolate reductase1.5.1.30.440
1f28UMPThymidylate synthase2.1.1.450.440
1gy3ATPCyclin-dependent kinase 22.7.11.220.440
1lp6C5POrotidine 5'-phosphate decarboxylase4.1.1.230.440
2hiw7MPTyrosine-protein kinase ABL12.7.10.20.440
2itxANPEpidermal growth factor receptor2.7.10.10.440
2ojj82AMitogen-activated protein kinase 12.7.11.240.440
2vgpAD6Aurora kinase B-A2.7.11.10.440
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.440
2wogZZDKinesin-like protein KIF11/0.440
2xd6XD6ATP-dependent molecular chaperone HSP82/0.440
2yelWSHBromodomain-containing protein 4/0.440
2yloTESAndrogen receptor/0.440
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.440
3evbSAHGenome polyprotein2.1.1.560.440
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.440
3jrxS1AAcetyl-CoA carboxylase 2/0.440
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.440
4eok4SPCyclin-dependent kinase 22.7.11.220.440
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.440
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.440
4hys1BJMitogen-activated protein kinase 82.7.11.240.440
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.440
4jloADPAdenylate kinase/0.440
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.440
4lfiGNPCasein kinase II subunit alpha2.7.11.10.440
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.440
4lsmNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
4z69DIFSerum albumin/0.440
5auzGENDeath-associated protein kinase 12.7.11.10.440
5hbsRTLRetinol-binding protein 1/0.440