sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4epw | GDP | GTPase KRas |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4epw | GDP | GTPase KRas | / | 1.000 | |
| 4l9s | GDP | GTPase HRas | / | 0.692 | |
| 4q02 | GDP | GTPase KRas | / | 0.686 | |
| 4tq9 | GDP | GTPase KRas | / | 0.662 | |
| 4wa7 | GDP | GTPase KRas | / | 0.646 | |
| 4l8g | GDP | GTPase KRas | / | 0.637 | |
| 4xvq | GNP | GTPase HRas | / | 0.634 | |
| 4obe | GDP | GTPase KRas | / | 0.632 | |
| 4lpk | GDP | GTPase KRas | / | 0.630 | |
| 2rgg | GNP | GTPase HRas | / | 0.625 | |
| 4xvr | GNP | GTPase HRas | / | 0.615 | |
| 2ce2 | GDP | GTPase HRas | / | 0.612 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.607 | |
| 3kkq | GDP | Ras-related protein M-Ras | / | 0.606 | |
| 4q03 | GDP | GTPase KRas | / | 0.604 | |
| 3tgp | GNP | GTPase HRas | / | 0.600 | |
| 4epx | GDP | GTPase KRas | / | 0.600 | |
| 4ql3 | GDP | GTPase KRas | / | 0.598 | |
| 4lv6 | GDP | GTPase KRas | / | 0.593 | |
| 4ldj | GDP | GTPase KRas | / | 0.592 | |
| 3k9l | GNP | GTPase HRas | / | 0.587 | |
| 4lrw | GDP | GTPase KRas | / | 0.586 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.582 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.578 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.577 | |
| 3ddc | GNP | GTPase HRas | / | 0.574 | |
| 2rge | GNP | GTPase HRas | / | 0.573 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.569 | |
| 3lbh | GNP | GTPase HRas | / | 0.565 | |
| 4nyi | GNP | GTPase HRas | / | 0.565 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.561 | |
| 3kud | GDP | GTPase HRas | / | 0.561 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.560 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.559 | |
| 4dlw | GNP | GTPase HRas | / | 0.559 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.558 | |
| 2msc | GDP | MHC class I alpha chain | / | 0.554 | |
| 3x1w | GDP | Ras-related protein Rap-1b | / | 0.554 | |
| 4dsn | GCP | GTPase KRas | / | 0.554 | |
| 3rs4 | GNP | GTPase HRas | / | 0.553 | |
| 3v4f | GNP | GTPase HRas | / | 0.551 | |
| 4dsu | GDP | GTPase KRas | / | 0.550 | |
| 3i3s | GNP | GTPase HRas | / | 0.548 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.548 | |
| 1lfd | GNP | GTPase HRas | / | 0.546 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.544 | |
| 3rs0 | GNP | GTPase HRas | / | 0.544 | |
| 4dlv | GNP | GTPase HRas | / | 0.544 | |
| 4dlz | GNP | GTPase HRas | / | 0.544 | |
| 4g0n | GNP | GTPase HRas | / | 0.544 | |
| 3lbn | GNP | GTPase HRas | / | 0.543 | |
| 3lbi | GNP | GTPase HRas | / | 0.540 | |
| 2c5l | GTP | GTPase HRas | / | 0.539 | |
| 3k8y | GNP | GTPase HRas | / | 0.538 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.538 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.537 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.536 | |
| 4nyj | GNP | GTPase HRas | / | 0.536 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.535 | |
| 2rgc | GNP | GTPase HRas | / | 0.534 | |
| 3rsl | GNP | GTPase HRas | / | 0.534 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.532 | |
| 3oiv | GNP | GTPase HRas | / | 0.532 | |
| 4dlx | GNP | GTPase HRas | / | 0.532 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.531 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.531 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.529 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.529 | |
| 2bme | GNP | Ras-related protein Rab-4A | / | 0.528 | |
| 2cl6 | CAG | GTPase HRas | / | 0.527 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.527 | |
| 4dlt | GNP | GTPase HRas | / | 0.526 | |
| 3l8y | GNP | GTPase HRas | / | 0.525 | |
| 5b2z | GNP | GTPase HRas | / | 0.525 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.522 | |
| 3oiw | GNP | GTPase HRas | / | 0.520 | |
| 3rs5 | GNP | GTPase HRas | / | 0.519 | |
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 0.518 | |
| 5dif | GNP | GTP-binding nuclear protein Ran | / | 0.518 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.514 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.513 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.512 | |
| 2rgb | GNP | GTPase HRas | / | 0.510 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.509 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.508 | |
| 2q3f | GNP | Ras-related GTP-binding protein D | / | 0.508 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.507 | |
| 1d5c | GDP | GTPase (Rab6) | / | 0.506 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.506 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.505 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.504 | |
| 4dso | GSP | GTPase KRas | / | 0.502 | |
| 1z2a | GDP | Ras-related protein Rab-23 | / | 0.500 | |
| 1ky2 | GNP | GTP-binding protein YPT7 | / | 0.499 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.499 | |
| 3vhx | GTP | ADP-ribosylation factor 6 | / | 0.498 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.497 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.497 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.497 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.497 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.497 | |
| 3oiu | GNP | GTPase HRas | / | 0.497 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.496 | |
| 4dls | GNP | GTPase HRas | / | 0.496 | |
| 4l9w | GNP | GTPase HRas | / | 0.495 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.493 | |
| 4dxa | GSP | Ras-related protein Rap-1b | / | 0.493 | |
| 4mit | GTP | Rho-related protein racC | / | 0.493 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.492 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.492 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.492 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.491 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.491 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.490 | |
| 2msd | GNP | MHC class I alpha chain | / | 0.490 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.489 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1v8k | ANP | Kinesin-like protein KIF2C | / | 0.488 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.488 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.488 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.487 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.487 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.487 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.486 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.486 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.486 | |
| 1p0e | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.485 | |
| 3rs7 | GNP | GTPase HRas | / | 0.485 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.485 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.484 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.484 | |
| 1g16 | GDP | Ras-related protein SEC4 | / | 0.482 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.482 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.482 | |
| 2vo4 | GTB | 2,4-D inducible glutathione S-transferase | / | 0.481 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.481 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.481 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.480 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.480 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.479 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.478 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.477 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1a4r | GNH | Cell division control protein 42 homolog | / | 0.476 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.476 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.476 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.475 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.475 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.475 | |
| 3ft5 | MO8 | Heat shock protein HSP 90-alpha | / | 0.475 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.475 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 4pzd | NAD | 3-Hydroxyacyl-CoA dehydrogenase | / | 0.475 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.475 | |
| 3up0 | D7S | aceDAF-12 | / | 0.474 | |
| 4ehv | 0SJ | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.474 | |
| 1efa | NPF | Lactose operon repressor | / | 0.473 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.473 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.473 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.473 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.473 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.472 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.471 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.470 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.470 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.470 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.470 | |
| 4cf8 | V7H | Integrase | / | 0.470 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.470 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.470 | |
| 4yak | COA | Acyl-CoA synthetase (NDP forming) | / | 0.470 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.469 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.469 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.469 | |
| 3gds | VAL_TYR_TYR_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.469 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.469 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.469 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.469 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 2xvw | 9NR | Serum albumin | / | 0.468 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.468 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.468 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.467 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.467 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 2oo7 | AP5 | Adenylate kinase | / | 0.467 | |
| 3t40 | 3RG | Indole-3-glycerol phosphate synthase | 4.1.1.48 | 0.467 | |
| 4gzl | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.467 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.466 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.466 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.466 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.466 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.466 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.465 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.465 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.465 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.465 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 3wyf | GTP | GTP-binding nuclear protein | / | 0.465 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.465 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.464 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.464 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.464 | |
| 3zos | 0LI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.464 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.464 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.464 | |
| 1biw | S80 | Stromelysin-1 | 3.4.24.17 | 0.463 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.463 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.463 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.463 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.463 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.463 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.463 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.463 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.463 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.463 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.462 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.462 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3gwn | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.462 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.462 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.462 | |
| 4b1f | KRH | Glutamate racemase | / | 0.462 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.462 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.462 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.461 | |
| 1uxn | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.461 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.461 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 2bxm | IMN | Serum albumin | / | 0.461 | |
| 2bxq | IMN | Serum albumin | / | 0.461 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.461 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 2v7q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.461 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 3lsy | FT0 | Enoyl-ACP reductase | / | 0.461 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4l9q | 9TP | Serum albumin | / | 0.461 | |
| 5ez4 | NAD | Betaine-aldehyde dehydrogenase | / | 0.461 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.460 | |
| 1osv | CHC | Bile acid receptor | / | 0.460 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.460 | |
| 1rp7 | TZD | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.460 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.460 | |
| 2xvv | 9DN | Serum albumin | / | 0.460 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4bdo | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.460 | |
| 4eh9 | 0OQ | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.460 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.460 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.460 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.459 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2j4l | UTP | Uridylate kinase | 2.7.4.22 | 0.459 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.459 | |
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.459 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.459 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.459 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.459 | |
| 1am4 | GNP | Cell division control protein 42 homolog | / | 0.458 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.458 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.458 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.458 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.458 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.458 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.458 | |
| 3fhi | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.458 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 3gol | XND | Genome polyprotein | 2.7.7.48 | 0.458 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.458 | |
| 3ref | GDP | Rho family GTPase | / | 0.458 | |
| 4bdr | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.458 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.458 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.458 | |
| 4hs4 | FMN | Chromate reductase | / | 0.458 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.458 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.458 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.457 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.457 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.457 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.457 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.457 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.457 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.457 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.457 | |
| 3v49 | PK0 | Androgen receptor | / | 0.457 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.456 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.456 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.456 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.456 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.456 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.456 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.456 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.456 | |
| 4g01 | GDP | Ras-related protein RABF2b | / | 0.456 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.456 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.455 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.455 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.455 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.455 | |
| 2e07 | SAH | Diphthine synthase | / | 0.455 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.455 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.455 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4l8u | 9AZ | Serum albumin | / | 0.455 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.455 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 1bcp | ATP | Pertussis toxin subunit 4 | / | 0.454 | |
| 1bcp | ATP | Pertussis toxin subunit 5 | / | 0.454 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1qy5 | NEC | Endoplasmin | / | 0.454 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2ejj | SAH | Diphthine synthase | / | 0.454 | |
| 2fyp | RDE | Endoplasmin | / | 0.454 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.454 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.454 | |
| 3e8x | NAP | BH1520 protein | / | 0.454 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.454 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.454 | |
| 4a7b | 3W5 | Collagenase 3 | 3.4.24 | 0.454 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4cjq | VXO | Integrase | / | 0.454 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 4qbi | AP5 | Adenylate kinase | / | 0.454 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.454 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.453 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.453 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.453 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 3pt9 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.453 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.453 | |
| 3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.453 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4chy | C5Q | Integrase | / | 0.453 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.453 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.453 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.453 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.453 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2hz0 | GIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.452 | |
| 2np6 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.452 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.452 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.452 | |
| 3iej | 599 | Cathepsin S | 3.4.22.27 | 0.452 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.452 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.452 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.452 | |
| 4xr9 | TMP | CalS8 | / | 0.452 | |
| 5di3 | GNP | ADP-ribosylation factor-like protein 3 | / | 0.452 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.452 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.452 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.451 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.451 | |
| 3eku | CY9 | Actin-5C | / | 0.451 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.451 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.451 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.451 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.451 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.451 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.451 | |
| 4lb2 | DM5 | Serum albumin | / | 0.451 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.451 | |
| 4o4e | ATP | Kinase | / | 0.451 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.451 | |
| 4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.451 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.451 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.450 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.450 | |
| 2eni | SAH | Diphthine synthase | / | 0.450 | |
| 2g82 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.450 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.450 | |
| 2wi2 | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2wpw | ACO | Orf14 | / | 0.450 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.450 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.450 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 3pcg | 4HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.450 | |
| 3pcg | 4HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.450 | |
| 3pft | FMN | Flavin reductase | / | 0.450 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.450 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3zuk | RDF | Endopeptidase, peptidase family M13 | / | 0.450 | |
| 3zv5 | BPY | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.450 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.450 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.450 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.450 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.450 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 4ogh | HFT | Androgen receptor | / | 0.450 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.450 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.449 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1rfq | LAR | Actin, alpha skeletal muscle | / | 0.449 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.449 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.449 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.449 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.449 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 3i68 | J4Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.449 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.449 | |
| 3zv6 | 4HB | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.449 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.449 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.449 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.449 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.449 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1ii6 | ADP | Kinesin-like protein KIF11 | / | 0.448 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 2ati | IHU | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.448 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.448 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.448 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.448 | |
| 3am5 | TCL | Enoyl-ACP reductase | / | 0.448 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.448 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.448 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.448 | |
| 4bn1 | ADP | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 4h5c | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.448 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.448 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.447 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.447 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.447 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2h2j | SFG | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.447 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.447 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.447 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3pvt | 3HC | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.447 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.447 | |
| 3wag | TYD | Glycosyltransferase | / | 0.447 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.447 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.447 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.447 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.447 | |
| 4u0k | 744 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4ztv | TA7 | Anthranilate phosphoribosyltransferase | / | 0.447 | |
| 5iqa | GNP | Bifunctional AAC/APH | 2.3.1 | 0.447 | |
| 1aqv | 0HG | Glutathione S-transferase P | 2.5.1.18 | 0.446 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1evj | NAD | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.446 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.446 | |
| 1i2l | DCS | Aminodeoxychorismate lyase | 4.1.3.38 | 0.446 | |
| 1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.446 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.446 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.446 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.446 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.446 | |
| 2p2x | SAH | Diphthine synthase | / | 0.446 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.446 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3eks | CY9 | Actin-5C | / | 0.446 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.446 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.446 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4o4f | ATP | Kinase | / | 0.446 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.446 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.445 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.445 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.445 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.445 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.445 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1onp | FOM | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.445 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.445 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.445 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2cdc | NAP | Glucose 1-dehydrogenase | / | 0.445 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.445 | |
| 2wpx | ACO | Orf14 | / | 0.445 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.445 | |
| 3dt4 | GTP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.445 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.445 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.445 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.445 | |
| 3t7v | SAM | 3-methylornithine synthase | / | 0.445 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.445 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.445 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.445 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.445 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.445 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.445 | |
| 4j3d | 1JS | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.445 | |
| 4lv5 | ADP | Rhoptry protein 5B | / | 0.445 | |
| 4u7t | SAH | DNA (cytosine-5)-methyltransferase 3A | 2.1.1.37 | 0.445 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.444 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.444 | |
| 1hk5 | T44 | Serum albumin | / | 0.444 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.444 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.444 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.444 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.444 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.444 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.444 | |
| 3p9t | TCL | Repressor | / | 0.444 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.444 | |
| 3rga | ILD | Epoxide hydrolase LasB | 5.5.1 | 0.444 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.444 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.444 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.444 | |
| 4ap0 | ADP | Kinesin-like protein KIF11 | / | 0.444 | |
| 4cgh | LOZ | Integrase | / | 0.444 | |
| 4cj3 | E4F | Integrase | / | 0.444 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 4k30 | NLG | N-acetylglutamate synthase, mitochondrial | 2.3.1.1 | 0.444 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.444 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.444 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.444 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.444 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.444 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.443 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.443 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.443 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.443 | |
| 2zm4 | KSM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.443 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 3kwn | 23Z | Cathepsin S | 3.4.22.27 | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.443 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.443 | |
| 4cjr | FYM | Integrase | / | 0.443 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.443 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.443 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1f9a | ATP | Nicotinamide-nucleotide adenylyltransferase | / | 0.442 | |
| 1hi0 | GTP | RNA-directed RNA polymerase | 2.7.7.48 | 0.442 | |
| 1hk2 | T44 | Serum albumin | / | 0.442 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.442 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.442 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2xxy | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.442 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.442 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.442 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.442 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.442 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.442 | |
| 3ldf | SAH | Uncharacterized protein | / | 0.442 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 3rga | LSB | Epoxide hydrolase LasB | 5.5.1 | 0.442 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.442 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.442 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.442 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.442 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.442 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.442 | |
| 5bpf | ADP | D-alanine--D-alanine ligase | / | 0.442 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.442 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.442 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.442 | |
| 1ake | AP5 | Adenylate kinase | / | 0.441 | |
| 1ank | ANP | Adenylate kinase | / | 0.441 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.441 | |
| 1nja | DCM | Thymidylate synthase | / | 0.441 | |
| 1ozv | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.441 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.441 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.441 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.441 | |
| 3b9l | AZZ | Serum albumin | / | 0.441 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.441 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.441 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.441 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.441 | |
| 3tpt | ADP | Serine/threonine-protein kinase toxin HipA | / | 0.441 | |
| 3u2x | ASO | Glycogenin-1 | 2.4.1.186 | 0.441 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.441 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4guk | P2G | Neuronal calcium sensor 1 | / | 0.441 | |
| 4ho4 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.441 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.441 | |
| 4k5p | 1OS | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.441 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.441 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.441 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1o5i | NAD | 3-oxoacyl-(Acyl carrier protein) reductase | / | 0.440 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.440 | |
| 2g8d | UMP | Thymidylate synthase | / | 0.440 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2h2e | SA8 | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.440 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.440 | |
| 2r9e | SDX | Citrate synthase | 2.3.3.16 | 0.440 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.440 | |
| 2rr1 | W8R | Genome polyprotein | / | 0.440 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.440 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.440 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.440 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.440 | |
| 3sa3 | 23X | Protease | / | 0.440 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 3wqt | ANP | Cell division protein FtsA | / | 0.440 | |
| 3zsg | T75 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4ag5 | ADP | Type IV secretory pathway VirB4 components-like protein | / | 0.440 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.440 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.440 | |
| 4goj | GNP | ADP-ribosylation factor-like protein 3 | / | 0.440 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4ifv | FMQ | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4lhv | GDP | Ras-related protein Rab-8A | / | 0.440 | |
| 4u0i | 0LI | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.440 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 5e72 | SAM | N2, N2-dimethylguanosine tRNA methyltransferase | / | 0.440 |