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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4eox0S5Peptide deformylase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4eox0S5Peptide deformylase/1.000
2aieSB9Peptide deformylase/0.719
3u7lUDBPeptide deformylase/0.625
2os1BB2Peptide deformylase/0.603
2os3BB2Peptide deformylase/0.589
2aiaSB8Peptide deformylase/0.587
3u7kMDBPeptide deformylase/0.562
3u04BB2Peptide deformylase/0.513
3hlwCE3Beta-lactamase/0.505
1dgmADNAdenosine kinase2.7.1.200.498
3m6pBB2Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.497
4e9bBB2Peptide deformylase/0.494
4e9aQAPPeptide deformylase/0.489
4rosAPRMalate dehydrogenase/0.489
4k6fNAPPutative Acetoacetyl-CoA reductase/0.488
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.487
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.487
1ix1BB2Peptide deformylase/0.486
1u2yGOXPancreatic alpha-amylase/0.486
3svj4LIPeptide deformylase/0.484
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.483
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.483
3p62FMNPentaerythritol tetranitrate reductase/0.483
3zkbANPDNA gyrase subunit B/0.483
1ws1BB2Peptide deformylase 1/0.482
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.482
1vi2NADQuinate/shikimate dehydrogenase/0.481
1g27BB1Peptide deformylase3.5.1.880.480
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.480
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.479
3p67FMNPentaerythritol tetranitrate reductase/0.479
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.479
1lqyBB2Peptide deformylase 23.5.1.880.478
3e3uNVCPeptide deformylase3.5.1.880.478
1h63FMNPentaerythritol tetranitrate reductase/0.477
2e7zMGDAcetylene hydratase/0.477
2omeNADC-terminal-binding protein 2/0.476
3h3t16HCollagen type IV alpha-3-binding protein/0.476
4ke11R6Beta-secretase 13.4.23.460.476
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.476
2g1n1IGRenin3.4.23.150.475
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.475
3b2sB2STrichothecene 3-O-acetyltransferase/0.475
3h3qH13Collagen type IV alpha-3-binding protein/0.475
3tnlNADShikimate dehydrogenase (NADP(+))/0.475
4a862ANMajor pollen allergen Bet v 1-A/0.475
2tysPLTTryptophan synthase beta chain4.2.1.200.474
4dptAGSMevalonate diphosphate decarboxylase/0.474
4k28NADShikimate dehydrogenase family protein/0.474
1qrpHH0Pepsin A-43.4.23.10.473
2cftPLPPyridoxal phosphate phosphatase/0.473
3lqfNADGalactitol dehydrogenase/0.473
1nfyRTRCoagulation factor X3.4.21.60.472
2a9y26AAdenosine kinase2.7.1.200.472
2dsgSAHDiphthine synthase/0.472
2iypA2P6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.472
3sw85LIPeptide deformylase/0.472
2fhnBNIAvidin-related protein 4/5/0.471
3f03FMNPentaerythritol tetranitrate reductase/0.471
4fuj1U9Urokinase-type plasminogen activator3.4.21.730.471
2dv3SAHDiphthine synthase/0.470
2zrfDTPProtein RecA/0.470
4du6GTPGTP cyclohydrolase 1/0.470
4m6jNDPDihydrofolate reductase1.5.1.30.470
4p9dTMPDeoxycytidylate deaminase/0.470
4rww2BALmo2692 protein/0.470
2gtbAZPOrf1ab polyprotein/0.469
3ixp834Ecdysone receptor/0.469
4dfg0JVGag-Pol polyprotein3.4.23.160.469
2ejzSAHDiphthine synthase/0.468
2j5bTYETyrosine--tRNA ligase6.1.1.10.468
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3fr5I4AFatty acid-binding protein, adipocyte/0.468
3zeiAWHO-acetylserine sulfhydrylase/0.468
1g1aNADdTDP-glucose 4,6-dehydratase/0.467
1tojHCIAspartate aminotransferase2.6.1.10.467
2w6zL21Biotin carboxylase6.3.4.140.467
3kjgADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.467
4dbc3QPAspartate aminotransferase2.6.1.10.467
4f9gC2EStimulator of interferon genes protein/0.467
2huqSAHDiphthine synthase/0.466
3eyhIZATyrosine-protein kinase JAK1/0.466
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.466
4e2bFMNDehydrogenase/0.466
4i1iNADMalate dehydrogenase/0.466
1ay0TPPTransketolase 12.2.1.10.465
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.465
1mjaCOAHistone acetyltransferase ESA1/0.465
1touB1VFatty acid-binding protein, adipocyte/0.465
2ofiADK3-methyladenine DNA glycosylase I/0.465
3h06VBPGlutamate receptor 2/0.465
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.465
4a86H35Major pollen allergen Bet v 1-A/0.465
4de00JBBeta-lactamase/0.465
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.465
4i1nFOLDihydrofolate reductase1.5.1.30.465
4jzr4JREgl nine homolog 1/0.465
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.464
1drhNAPDihydrofolate reductase1.5.1.30.464
2emuSAHDiphthine synthase/0.464
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.464
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.464
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.464
3nsh957Beta-secretase 13.4.23.460.464
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.464
4bfzZVZPantothenate kinase2.7.1.330.464
4i0i957Beta-secretase 13.4.23.460.464
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.464
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.463
4df2FMNNADPH dehydrogenase/0.463
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
4f5yC2EStimulator of interferon genes protein/0.463
4tx9AMZPhosphoribosyl isomerase A/0.463
1mxiSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.462
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.462
2emrSAHDiphthine synthase/0.462
2rh9IGPTryptophan synthase alpha chain/0.462
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.462
3a0tADPSensor histidine kinase/0.462
3gviADPMalate dehydrogenase/0.462
3uwbBB2RIIA-RIIB membrane-associated protein/0.462
4h4e10G4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.462
4m5pFMNNADPH dehydrogenase/0.462
4nmdFDABifunctional protein PutA/0.462
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.461
2a94AP0L-lactate dehydrogenase1.1.1.270.461
3f3sNADLambda-crystallin homolog/0.461
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.461
3p0hFSEPutative tyrosyl-tRNA synthetase/0.461
3pdqKC6Lysine-specific demethylase 4A1.14.110.461
1bofGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.460
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1toiHCIAspartate aminotransferase2.6.1.10.460
1y9dTPPPyruvate oxidase1.2.3.30.460
2balPQAMitogen-activated protein kinase 14/0.460
2pb4SAHDiphthine synthase/0.460
2zvcSAHPrecorrin-3 C17-methyltransferase/0.460
3fpzAHZThiamine thiazole synthase/0.460
4ef4C2EStimulator of interferon genes protein/0.460
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.460
4qaiFMNNADPH dehydrogenase/0.460
1h51FMNPentaerythritol tetranitrate reductase/0.459
1o9bNAIQuinate/shikimate dehydrogenase/0.459
1txtCAAHMG-CoA synthase/0.459
2dxdANPNucleoside diphosphate kinase2.7.4.60.459
2dxwSAHDiphthine synthase/0.459
2e8hSAHDiphthine synthase/0.459
2ohvNHLGlutamate racemase/0.459
2pk3GDDGDP-6-deoxy-D-mannose reductase/0.459
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.459
4cf7ADPAdenylate kinase/0.459
1a9cGTPGTP cyclohydrolase 13.5.4.160.458
1tehNADAlcohol dehydrogenase class-31.1.1.10.458
2a1oCAMCamphor 5-monooxygenase1.14.15.10.458
2f3rG5PGuanylate kinase2.7.4.80.458
2he5NDPAldo-keto reductase family 1 member C211.1.10.458
2rcyNAPPyrroline-5-carboxylate reductase/0.458
2rqfJH3Hemolymph juvenile hormone binding protein/0.458
2xlrFADPutative flavin-containing monooxygenase/0.458
3fp0FP015-O-acetyltransferase/0.458
3igpDT7Carbonic anhydrase 24.2.1.10.458
3o3jBB4Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.458
4jwfSAHtRNA (guanine(9)-N1)-methyltransferase/0.458
4l4fCAMCamphor 5-monooxygenase1.14.15.10.458
1j78VDYVitamin D-binding protein/0.457
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.457
2dv4SAHDiphthine synthase/0.457
2dvlFADAcyl-CoA dehydrogenase/0.457
4cmfPXGUncharacterized protein/0.457
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.456
1il0NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
2idkC2FGlycine N-methyltransferase2.1.1.200.456
2q46NAPUncharacterized protein At5g02240/0.456
2rlcCHDCholoylglycine hydrolase3.5.1.240.456
2x06NADL-sulfolactate dehydrogenase/0.456
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.456
3ke8EIP4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.456
3qlrNDPDihydrofolate reductase1.5.1.30.456
3sfdFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.456
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.456
4cnfMTASpoU rRNA methylase/0.456
4jc51K5Stimulator of interferon genes protein/0.456
4oztP1AEcdysone receptor, putative/0.456
1odx0E8Gag-Pol polyprotein3.4.23.160.455
1y7uCOAAcyl-CoA hydrolase/0.455
1zsbAZMCarbonic anhydrase 24.2.1.10.455
2a5kAZPReplicase polyprotein 1ab3.4.220.455
2abbFMNPentaerythritol tetranitrate reductase/0.455
2ahrNAPPyrroline-5-carboxylate reductase/0.455
2b8tTHMThymidine kinase/0.455
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.455
2stdCRPScytalone dehydratase4.2.1.940.455
2v16C47Renin3.4.23.150.455
3wt0ATPCell division protein FtsA/0.455
4c02TAKActivin receptor type-12.7.11.300.455
4m2rBZ1Carbonic anhydrase 24.2.1.10.455
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.455
4wxg2BOSerine hydroxymethyltransferase/0.455
1g54FFBCarbonic anhydrase 24.2.1.10.454
1n2jPAFPantothenate synthetase6.3.2.10.454
1w6hTITPlasmepsin-23.4.23.390.454
1xe65FPPlasmepsin-23.4.23.390.454
2xx413IATP-dependent molecular chaperone HSP82/0.454
3hhu819Heat shock protein HSP 90-alpha/0.454
3hk1B64Fatty acid-binding protein, adipocyte/0.454
3u2mFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.454
4a83DXCMajor pollen allergen Bet v 1-A/0.454
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.454
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.454
1a8rGTPGTP cyclohydrolase 13.5.4.160.453
1p9pSAHtRNA (guanine-N(1)-)-methyltransferase/0.453
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.453
1x1cSAHC-20 methyltransferase/0.453
2b53D23Cyclin-dependent kinase 22.7.11.220.453
2ek3SAHDiphthine synthase/0.453
2rgoFADAlpha-Glycerophosphate Oxidase/0.453
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3oafOAGDihydrofolate reductase1.5.1.30.453
3raiX85Cyclin-dependent kinase 22.7.11.220.453
4j491J1Uncharacterized protein/0.453
4k771Q4Tyrosine-protein kinase JAK1/0.453
4kgkGTPUncharacterized protein/0.453
4z4pSAHHistone-lysine N-methyltransferase 2D2.1.1.430.453
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.452
1cqp803Integrin alpha-L/0.452
1fwkADPHomoserine kinase2.7.1.390.452
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.452
1s3uTQDDihydrofolate reductase1.5.1.30.452
2c29NAPDihydroflavonol 4-reductase/0.452
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.452
2e16SAHDiphthine synthase/0.452
2nnqT4BFatty acid-binding protein, adipocyte/0.452
2wp9CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.452
2wp9CBESuccinate dehydrogenase cytochrome b556 subunit/0.452
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.452
2xtnGTPGTPase IMAP family member 2/0.452
3a3bRBFLumazine protein/0.452
3dlp1744-chlorobenzoyl CoA ligase/0.452
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3i0pNADMalate dehydrogenase, putative/0.452
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.452
3lsiFADPyranose 2-oxidase/0.452
3orfNADDihydropteridine reductase1.5.1.340.452
3qt62P0Mevalonate diphosphate decarboxylase/0.452
4exg916Beta-secretase 13.4.23.460.452
4g95OAGDihydrofolate reductase1.5.1.30.452
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.452
4l4eCAMCamphor 5-monooxygenase1.14.15.10.452
4nbwNADShort-chain dehydrogenase/reductase SDR/0.452
4ycoFMNtRNA-dihydrouridine(16) synthase/0.452
1rfuADPPyridoxal kinase2.7.1.350.451
1rp0AHZThiamine thiazole synthase, chloroplastic/0.451
1vbiNADMalate/L-lactate dehydrogenase family protein/0.451
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2bb9AKCGag-Pol polyprotein3.4.23.160.451
2gjlFMNNitronate monooxygenase1.13.12.160.451
2hfuMEVMevalonate kinase/0.451
2hu2NADC-terminal binding protein 1/0.451
3ipkPMSSurface protein adhesin/0.451
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.451
4a87NARMajor pollen allergen Bet v 1-A/0.451
4tmcFMNOld yellow enzyme/0.451
4u0mGTPCyclic GMP-AMP synthase/0.451
4zlaBESCytosol aminopeptidase3.4.11.10.451
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.451
1dhjMTXDihydrofolate reductase1.5.1.30.450
1khrVIRStreptogramin A acetyltransferase2.3.10.450
1n77ATPGlutamate--tRNA ligase6.1.1.170.450
1rx8NAPDihydrofolate reductase1.5.1.30.450
2dc1NADProbable L-aspartate dehydrogenase/0.450
2e07SAHDiphthine synthase/0.450
2eldSAHDiphthine synthase/0.450
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.450
2q4bNAPUncharacterized protein At5g02240/0.450
2trsPLSTryptophan synthase beta chain4.2.1.200.450
2vttLZDCyclin-dependent kinase 22.7.11.220.450
3atyFMNProstaglandin F2a synthase/0.450
3co93MSGenome polyprotein2.7.7.480.450
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.450
3k8q22APurine nucleoside phosphorylase2.4.2.10.450
3qgf46FGenome polyprotein2.7.7.480.450
3wquATPCell division protein FtsA/0.450
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.450
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.450
4rpgFADUDP-galactopyranose mutase5.4.99.90.450
5e7oMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.450
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.449
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
1g2aBB2Peptide deformylase3.5.1.880.449
1h50FMNPentaerythritol tetranitrate reductase/0.449
1h65GDPTranslocase of chloroplast 343.6.50.449
1i5eU5PUracil phosphoribosyltransferase/0.449
1n3rGTPGTP cyclohydrolase 13.5.4.160.449
1pq944BOxysterols receptor LXR-beta/0.449
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.449
1zlyDQBTrifunctional purine biosynthetic protein adenosine-32.1.2.20.449
2ab8MTPAdenosine kinase2.7.1.200.449
2b8v3BNBeta-secretase 13.4.23.460.449
2dv7SAHDiphthine synthase/0.449
2egsSAHDiphthine synthase/0.449
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.449
2owkSAHDiphthine synthase/0.449
2qenADPWalker-Type ATPase/0.449
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2ylxFADPhenylacetone monooxygenase1.14.13.920.449
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3m6rBB2Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.449
3w233RODihydroorotate dehydrogenase (fumarate)1.3.98.10.449
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.449
4xymCOAAcyl-CoA synthetase (NDP forming)/0.449
5a9sNAPPutative dehydrogenase/0.449
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.449
1kfbIGPTryptophan synthase alpha chain/0.448
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1yqzCOACoenzyme A disulfide reductase/0.448
2bxmIMNSerum albumin/0.448
2e4nSAHDiphthine synthase/0.448
2g1o2IGRenin3.4.23.150.448
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.448
2iyfERYOleandomycin glycosyltransferase2.4.10.448
2wwjY28Lysine-specific demethylase 4A/0.448
2zbaZBATrichothecene 3-O-acetyltransferase/0.448
3gvhNADMalate dehydrogenase/0.448
3ibqATPPyridoxal kinase/0.448
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.448
3mvm39PMitogen-activated protein kinase 14/0.448
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.448
4dbzNDPPutative ketoacyl reductase1.3.10.448
4lcjNADC-terminal-binding protein 2/0.448
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.448
4q4kFMNUncharacterized protein/0.448
4wxfPLGSerine hydroxymethyltransferase/0.448
4yagNAIC alpha-dehydrogenase/0.448
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.448
1a8pFADFerredoxin--NADP reductase/0.447
1cnfFADNitrate reductase [NADH]1.7.1.10.447
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.447
1ezvUQ6Cytochrome b/0.447
1f20FADNitric oxide synthase, brain1.14.13.390.447
1fk8NAD3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase1.1.1.500.447
1guyNADMalate dehydrogenase/0.447
1icqFMN12-oxophytodienoate reductase 11.3.1.420.447
1j49NADD-lactate dehydrogenase1.1.1.280.447
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.447
1lf3EH5Plasmepsin-23.4.23.390.447
1me6IVSPlasmepsin-23.4.23.390.447
1qyxNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1ra3MTXDihydrofolate reductase1.5.1.30.447
1sxjAGSReplication factor C subunit 1/0.447
1wxjIPLTryptophan synthase alpha chain/0.447
1xddAAYIntegrin alpha-L/0.447
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.447
2eh5SAHDiphthine synthase/0.447
2fznFADBifunctional protein PutA1.5.5.20.447
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.447
2pb6SAHDiphthine synthase/0.447
2vijC44Beta-secretase 13.4.23.460.447
2zcvNDPQuinone oxidoreductase 21.6.5.20.447
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.447
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.447
3po6DT9Carbonic anhydrase 24.2.1.10.447
3t3r9PLCytochrome P450 2A61.14.130.447
3tozNADShikimate dehydrogenase (NADP(+))/0.447
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.447
3zncBZ1Carbonic anhydrase 44.2.1.10.447
4bf9FMNtRNA-dihydrouridine(16) synthase/0.447
4dpy2P0Mevalonate diphosphate decarboxylase/0.447
4jxrACOAcetyltransferase/0.447
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.447
4ycpFMNtRNA-dihydrouridine(16) synthase/0.447
1dhfFOLDihydrofolate reductase1.5.1.30.446
1fy7COAHistone acetyltransferase ESA1/0.446
1lruBB2Peptide deformylase3.5.1.880.446
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1mjbACOHistone acetyltransferase ESA1/0.446
1p0ySAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.446
1qm5PLPMaltodextrin phosphorylase2.4.1.10.446
1ur5NADMalate dehydrogenase/0.446
2ag1TPPBenzaldehyde lyase/0.446
2d5nNDPRiboflavin biosynthesis protein RibD1.1.1.1930.446
2dfvNADL-threonine 3-dehydrogenase/0.446
2e15SAHDiphthine synthase/0.446
2ga2A19Methionine aminopeptidase 2/0.446
2huxSAHDiphthine synthase/0.446
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.446
3clsFADElectron transfer flavoprotein subunit alpha/0.446
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.446
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3mpt1GKMitogen-activated protein kinase 14/0.446
4dqf017Gag-Pol polyprotein/0.446
4fxy0W2Neurolysin, mitochondrial3.4.24.160.446
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.446
4ji91M3Tyrosine-protein kinase JAK2/0.446
4xczFONQdtf/0.446
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.446
1cs4FOKAdenylate cyclase type 2/0.445
1cs4FOKAdenylate cyclase type 5/0.445
1h62ANBPentaerythritol tetranitrate reductase/0.445
1h73ANPHomoserine kinase2.7.1.390.445
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.445
1n3sGTPGTP cyclohydrolase 13.5.4.160.445
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.445
1towCRZFatty acid-binding protein, adipocyte/0.445
1uxjNADMalate dehydrogenase/0.445
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.445
1zwlFMNNAD(P)H dehydrogenase (quinone)1.6.5.20.445
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.445
2el0SAHDiphthine synthase/0.445
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.445
2gcqDOIAdenylosuccinate synthetase/0.445
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
3nl6TPSUncharacterized protein/0.445
3phiNDPShikimate dehydrogenase (NADP(+))/0.445
3pn4BB2Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.445
3pw8ACO1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.445
3uylTYDProbable NDP-rhamnosyltransferase/0.445
3vydVYDRenin3.4.23.150.445
3wb2YGPUncharacterized protein MJ0488/0.445
4bftZVTPantothenate kinase2.7.1.330.445
4lu3AZMCarbonic anhydrase 144.2.1.10.445
4yekTHMThymidine phosphorylase/0.445
5fsi8DG7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.445
1jhrP2PNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.444
1nq5NADGlyceraldehyde-3-phosphate dehydrogenase/0.444
1nzfUPGDNA beta-glucosyltransferase/0.444
1pd9CO4Dihydrofolate reductase1.5.1.30.444
1sguMK1Gag-Pol polyprotein3.4.23.160.444
1t09NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.444
1vyrFMNPentaerythritol tetranitrate reductase/0.444
2af3COAPhosphate acetyltransferase2.3.1.80.444
2e1mFADL-glutamate oxidase/0.444
2gmvPEPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.444
2gvdFKPAdenylate cyclase type 2/0.444
2gvdFKPAdenylate cyclase type 5/0.444
2ibzUQ6Cytochrome b/0.444
2qnqQN3Gag-Pol polyprotein3.4.23.160.444
2ylzFADPhenylacetone monooxygenase1.14.13.920.444
3dgaUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3h03UBPGlutamate receptor 2/0.444
3kdb006Gag-Pol polyprotein3.4.23.160.444
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.444
3n2pAYXCarbonic anhydrase 24.2.1.10.444
4a802ANMajor pollen allergen Bet v 1-A/0.444
4an4DUDPutative glycosyl transferase/0.444
4f97VDOPutative glycosyltransferase/0.444
4g2fC07Ephrin type-A receptor 32.7.10.10.444
4je7BB2Peptide deformylase 1A, chloroplastic/mitochondrial3.5.1.880.444
4k6mSAHGenome polyprotein/0.444
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.444
4y3rF06Endothiapepsin3.4.23.220.444
1bzsBSINeutrophil collagenase3.4.24.340.443
1g4jFFBCarbonic anhydrase 24.2.1.10.443
1owe675Urokinase-type plasminogen activator3.4.21.730.443
1psa0ZLPepsin A3.4.23.10.443
1q6yCOAFormyl-CoA:oxalate CoA-transferase/0.443
1rzuADPGlycogen synthase 12.4.1.210.443
1szfFMNCytochrome b2, mitochondrial1.1.2.30.443
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.443
2a7r5GPGMP reductase 2/0.443
2drcMTXDihydrofolate reductase1.5.1.30.443
2g1s4IGRenin3.4.23.150.443
2gz7D3FOrf1a polyprotein/0.443
2owfSAHDiphthine synthase/0.443
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.443
2r3aSAMHistone-lysine N-methyltransferase SUV39H22.1.1.430.443
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.443
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3iphG11Mitogen-activated protein kinase 14/0.443
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3p82FMNPentaerythritol tetranitrate reductase/0.443
3phjDHKShikimate dehydrogenase (NADP(+))/0.443
3qizQI2Botulinum neurotoxin type A3.4.24.690.443
4bfvZVVPantothenate kinase2.7.1.330.443
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.443
4kbyC2EStimulator of interferon genes protein/0.443
4m4922YL-lactate dehydrogenase A chain1.1.1.270.443
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.443
1dhrNADDihydropteridine reductase1.5.1.340.442
1ep1FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.442
1f0xFADD-lactate dehydrogenase1.1.1.280.442
1f0yNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1ia1NDPDihydrofolate reductase1.5.1.30.442
1j9zFADNADPH--cytochrome P450 reductase/0.442
1jhqPMONicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.442
1kh3ANPArgininosuccinate synthase/0.442
1kvkATPMevalonate kinase2.7.1.360.442
1ra8FOLDihydrofolate reductase1.5.1.30.442
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.442
1xe55FEPlasmepsin-23.4.23.390.442
1xelUPGUDP-glucose 4-epimerase5.1.3.20.442
1xvaSAMGlycine N-methyltransferase2.1.1.200.442
1yrxFMNAppA protein/0.442
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.442
2dxvSAHDiphthine synthase/0.442
2ev9NAPShikimate dehydrogenase (NADP(+))/0.442
2hr8SAHDiphthine synthase/0.442
2owuSAHDiphthine synthase/0.442
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.442
2vbdV10Isopenicillin N synthase1.21.3.10.442
3cluFADElectron transfer flavoprotein subunit alpha/0.442
3ekuCY9Actin-5C/0.442
3fr4F8AFatty acid-binding protein, adipocyte/0.442
3gi6D78Gag-Pol polyprotein/0.442
3ivcFG4Pantothenate synthetase6.3.2.10.442
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.442
3kigDA4Carbonic anhydrase 24.2.1.10.442
3mdzEZLCarbonic anhydrase 74.2.1.10.442
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1/0.442
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
3p80P80Pentaerythritol tetranitrate reductase/0.442
3qvpFADGlucose oxidase1.1.3.40.442
3qwbNDPProbable quinone oxidoreductase1.6.5.50.442
3s3vTOPDihydrofolate reductase1.5.1.30.442
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.442
4a81DXCMajor pollen allergen Bet v 1-A/0.442
4cojDTPUncharacterized protein/0.442
4dpuAGSMevalonate diphosphate decarboxylase/0.442
4eqsCOACoenzyme A disulfide reductase/0.442
4i8zG08Gag-Pol polyprotein3.4.23.160.442
4q71FADBifunctional protein PutA/0.442
4xboSAHtRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ2.1.1.2000.442
4y3jHICEndothiapepsin3.4.23.220.442
5la6GDPTubulin beta-2B chain/0.442
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.441
1lryBB2Peptide deformylase/0.441
1mvtDTMDihydrofolate reductase1.5.1.30.441
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.441
1py5PY1TGF-beta receptor type-12.7.11.300.441
1rx8FOLDihydrofolate reductase1.5.1.30.441
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.441
1v453DGPurine nucleoside phosphorylase2.4.2.10.441
1w4xFADPhenylacetone monooxygenase1.14.13.920.441
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.441
2e83FMNFMN-binding protein/0.441
2eh2SAHDiphthine synthase/0.441
2ejkSAHDiphthine synthase/0.441
2hckQUETyrosine-protein kinase HCK2.7.10.20.441
2nv4SAMS-adenosyl-L-methionine-binding protein AF_0241/0.441
2pchSAHDiphthine synthase/0.441
2rg5279Mitogen-activated protein kinase 14/0.441
2vwqNAPGlucose 1-dehydrogenase/0.441
2vyqFADFerredoxin--NADP reductase1.18.1.20.441
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3dc3AZMCarbonic anhydrase 24.2.1.10.441
3g1oRF1HTH-type transcriptional regulator EthR/0.441
3imgBZ2Pantothenate synthetase6.3.2.10.441
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.441
3pvt3HC1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.441
3zgl10E4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.441
4ejmNAPPutative zinc-binding dehydrogenase/0.441
4pghSAMCaffeic acid O-methyltransferase/0.441
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.441
4qxp1YEStimulator of interferon genes protein/0.441
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.440
1bwsNDPGDP-L-fucose synthase/0.440
1dr2TAPDihydrofolate reductase1.5.1.30.440
1m76NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
1npdNADQuinate/shikimate dehydrogenase/0.440
1pjcNADAlanine dehydrogenase/0.440
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.440
1vyqDUXDeoxyuridine 5'-triphosphate nucleotidohydrolase/0.440
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.440
2b7aIZATyrosine-protein kinase JAK2/0.440
2bjfDXCCholoylglycine hydrolase3.5.1.240.440
2c2aADPSensor histidine kinase/0.440
2dhfDZFDihydrofolate reductase1.5.1.30.440
2f2uM77Rho-associated protein kinase 22.7.11.10.440
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.440
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.440
2p5yNADUDP-glucose 4-epimerase/0.440
2rg6287Mitogen-activated protein kinase 14/0.440
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.440
2wf4ZY4Beta-secretase 13.4.23.460.440
2zreAGSProtein RecA/0.440
3d2mCOAAmino-acid acetyltransferase/0.440
3em3478Gag-Pol polyprotein3.4.23.160.440
3own3OWRenin3.4.23.150.440
3s1dZIRCytokinin dehydrogenase 11.5.99.120.440
3w2lVRODihydroorotate dehydrogenase (fumarate)1.3.98.10.440
3w3nRX8Toll-like receptor 8/0.440
4b63NAPL-ornithine N(5)-monooxygenase/0.440
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.440
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.440
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.440
4qi9MTXDihydrofolate reductase/0.440
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.440