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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4eol1ROCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4eol1ROCyclin-dependent kinase 22.7.11.221.000
4eop1ROCyclin-dependent kinase 22.7.11.220.596
3qu0X40Cyclin-dependent kinase 22.7.11.220.582
3ral04ZCyclin-dependent kinase 22.7.11.220.578
4eos1ROCyclin-dependent kinase 22.7.11.220.578
3r9dX6BCyclin-dependent kinase 22.7.11.220.575
4eoi1ROCyclin-dependent kinase 22.7.11.220.572
1e9hINRCyclin-dependent kinase 22.7.11.220.568
3qtzX42Cyclin-dependent kinase 22.7.11.220.566
1w0xOLOCyclin-dependent kinase 22.7.11.220.563
3rpv26ZCyclin-dependent kinase 22.7.11.220.563
1vyw292Cyclin-dependent kinase 22.7.11.220.562
1h1pCMGCyclin-dependent kinase 22.7.11.220.559
3r73X87Cyclin-dependent kinase 22.7.11.220.559
1oiyN41Cyclin-dependent kinase 22.7.11.220.557
2iw84SPCyclin-dependent kinase 22.7.11.220.557
2iw94SPCyclin-dependent kinase 22.7.11.220.557
1h1q2A6Cyclin-dependent kinase 22.7.11.220.554
2duv371Cyclin-dependent kinase 22.7.11.220.554
3roy22ZCyclin-dependent kinase 22.7.11.220.553
3qruX19Cyclin-dependent kinase 22.7.11.220.551
3r6xX84Cyclin-dependent kinase 22.7.11.220.551
4fkr45KCyclin-dependent kinase 22.7.11.220.551
1h1r6CPCyclin-dependent kinase 22.7.11.220.550
2i40BLZCyclin-dependent kinase 22.7.11.220.550
3rk507ZCyclin-dependent kinase 22.7.11.220.549
3qxoX65Cyclin-dependent kinase 22.7.11.220.548
2btsU32Cyclin-dependent kinase 22.7.11.220.547
4eok4SPCyclin-dependent kinase 22.7.11.220.547
3dogNNNCyclin-dependent kinase 22.7.11.220.546
3rm719ZCyclin-dependent kinase 22.7.11.220.545
1h1s4SPCyclin-dependent kinase 22.7.11.220.544
4eor4SPCyclin-dependent kinase 22.7.11.220.544
1oi9N20Cyclin-dependent kinase 22.7.11.220.542
1pkdUCNCyclin-dependent kinase 22.7.11.220.542
3iggEFQCyclin-dependent kinase 22.7.11.220.541
2r3p3SCCyclin-dependent kinase 22.7.11.220.540
3lfnA27Cyclin-dependent kinase 22.7.11.220.540
3qqkX02Cyclin-dependent kinase 22.7.11.220.540
1oguST8Cyclin-dependent kinase 22.7.11.220.539
1vyzN5BCyclin-dependent kinase 22.7.11.220.539
3rak03ZCyclin-dependent kinase 22.7.11.220.539
2wihP48Cyclin-dependent kinase 22.7.11.220.538
4fx360KCyclin-dependent kinase 22.7.11.220.538
3s0o50ZCyclin-dependent kinase 22.7.11.220.537
3qtrX36Cyclin-dependent kinase 22.7.11.220.535
3r71X86Cyclin-dependent kinase 22.7.11.220.535
3lfsA07Cyclin-dependent kinase 22.7.11.220.534
3rk909ZCyclin-dependent kinase 22.7.11.220.534
4fki09KCyclin-dependent kinase 22.7.11.220.533
2r64740Cyclin-dependent kinase 22.7.11.220.532
3qwkX62Cyclin-dependent kinase 22.7.11.220.532
3rmf20ZCyclin-dependent kinase 22.7.11.220.532
4bgh3I6Cyclin-dependent kinase 22.7.11.220.532
4eon1ROCyclin-dependent kinase 22.7.11.220.532
4fkpLS5Cyclin-dependent kinase 22.7.11.220.532
2c6iDT1Cyclin-dependent kinase 22.7.11.220.531
2wpa889Cyclin-dependent kinase 22.7.11.220.531
3unk0BYCyclin-dependent kinase 22.7.11.220.531
3qzgX67Cyclin-dependent kinase 22.7.11.220.529
3rk708ZCyclin-dependent kinase 22.7.11.220.529
4fkw62KCyclin-dependent kinase 22.7.11.220.529
2c6o4SPCyclin-dependent kinase 22.7.11.220.528
3fz1B98Cyclin-dependent kinase 22.7.11.220.528
3ig7EFPCyclin-dependent kinase 22.7.11.220.528
4gmy0X5Tyrosine-protein kinase JAK2/0.528
3qwjX6ACyclin-dependent kinase 22.7.11.220.527
4lyn1YGCyclin-dependent kinase 22.7.11.220.527
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.526
3ql8X01Cyclin-dependent kinase 22.7.11.220.526
2c4g514Cyclin-dependent kinase 22.7.11.220.525
2cchATPCyclin-dependent kinase 22.7.11.220.525
2xmyCDKCyclin-dependent kinase 22.7.11.220.524
3qtuX44Cyclin-dependent kinase 22.7.11.220.524
2w06FRVCyclin-dependent kinase 22.7.11.220.523
3ezrEZRCyclin-dependent kinase 22.7.11.220.523
3r1sX73Cyclin-dependent kinase 22.7.11.220.523
3r8lZ30Cyclin-dependent kinase 22.7.11.220.523
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.522
1urwI1PCyclin-dependent kinase 22.7.11.220.520
2c5nCK8Cyclin-dependent kinase 22.7.11.220.520
3ddqRRCCyclin-dependent kinase 22.7.11.220.520
1p2a5BNCyclin-dependent kinase 22.7.11.220.519
1v1k3FPCyclin-dependent kinase 22.7.11.220.519
2fvdLIACyclin-dependent kinase 22.7.11.220.519
1di8DTQCyclin-dependent kinase 22.7.11.220.518
2w05FRTCyclin-dependent kinase 22.7.11.220.518
1ke9LS5Cyclin-dependent kinase 22.7.11.220.517
3ddpRC8Cyclin-dependent kinase 22.7.11.220.517
3py0SU9Cyclin-dependent kinase 22.7.11.220.517
3raiX85Cyclin-dependent kinase 22.7.11.220.517
1g5sI17Cyclin-dependent kinase 22.7.11.220.516
2bkzSBCCyclin-dependent kinase 22.7.11.220.516
2btrU73Cyclin-dependent kinase 22.7.11.220.516
3sqq99ZCyclin-dependent kinase 22.7.11.220.516
3qx2X63Cyclin-dependent kinase 22.7.11.220.515
3rni21ZCyclin-dependent kinase 22.7.11.220.515
3r7vZ02Cyclin-dependent kinase 22.7.11.220.514
1pxmCK5Cyclin-dependent kinase 22.7.11.220.513
3r8pZ46Cyclin-dependent kinase 22.7.11.220.513
3rm618ZCyclin-dependent kinase 22.7.11.220.513
3s1h56ZCyclin-dependent kinase 22.7.11.220.513
4fko20KCyclin-dependent kinase 22.7.11.220.513
4fks46KCyclin-dependent kinase 22.7.11.220.513
4acm7YGCyclin-dependent kinase 22.7.11.220.512
2a0cCK9Cyclin-dependent kinase 22.7.11.220.511
2b52D42Cyclin-dependent kinase 22.7.11.220.511
3pxyJWSCyclin-dependent kinase 22.7.11.220.511
3rjc06ZCyclin-dependent kinase 22.7.11.220.511
3sw418KCyclin-dependent kinase 22.7.11.220.511
4fkv61KCyclin-dependent kinase 22.7.11.220.511
1oiuN76Cyclin-dependent kinase 22.7.11.220.510
3rpo24ZCyclin-dependent kinase 22.7.11.220.510
4fkq42KCyclin-dependent kinase 22.7.11.220.510
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.509
3qqfX07Cyclin-dependent kinase 22.7.11.220.509
1fvt106Cyclin-dependent kinase 22.7.11.220.508
2uzoC62Cyclin-dependent kinase 22.7.11.220.508
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.508
3r8zZ63Cyclin-dependent kinase 22.7.11.220.507
1h0w207Cyclin-dependent kinase 22.7.11.220.506
2w1hL0FCyclin-dependent kinase 22.7.11.220.506
4bcpT3CCyclin-dependent kinase 22.7.11.220.505
2b55D31Cyclin-dependent kinase 22.7.11.220.504
3mtfA3FActivin receptor type-12.7.11.300.504
3qtqX35Cyclin-dependent kinase 22.7.11.220.504
3qzhX69Cyclin-dependent kinase 22.7.11.220.504
1gij2PUCyclin-dependent kinase 22.7.11.220.502
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.502
1pxpCK8Cyclin-dependent kinase 22.7.11.220.501
2c6mDT5Cyclin-dependent kinase 22.7.11.220.501
2x1nX1NCyclin-dependent kinase 22.7.11.220.500
4ez30S0Cyclin-dependent kinase 22.7.11.220.500
2vu3LZECyclin-dependent kinase 22.7.11.220.499
3qqhX0ACyclin-dependent kinase 22.7.11.220.499
3qzfX66Cyclin-dependent kinase 22.7.11.220.499
3r1qX75Cyclin-dependent kinase 22.7.11.220.499
3sw719KCyclin-dependent kinase 22.7.11.220.499
4bcnT9NCyclin-dependent kinase 22.7.11.220.499
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.498
3rpy27ZCyclin-dependent kinase 22.7.11.220.498
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.498
3tnwF18Cyclin-dependent kinase 22.7.11.220.498
1gy3ATPCyclin-dependent kinase 22.7.11.220.497
3my5RFZCyclin-dependent kinase 22.7.11.220.497
3qqlX03Cyclin-dependent kinase 22.7.11.220.497
3r7iX9ICyclin-dependent kinase 22.7.11.220.497
3rpr25ZCyclin-dependent kinase 22.7.11.220.497
4bcmT7ZCyclin-dependent kinase 22.7.11.220.497
4erwSTUCyclin-dependent kinase 22.7.11.220.497
1ke6LS2Cyclin-dependent kinase 22.7.11.220.496
1r78FMDCyclin-dependent kinase 22.7.11.220.496
1v0oINRCell division control protein 2 homolog2.7.11.220.496
2r3mSCXCyclin-dependent kinase 22.7.11.220.496
1ykr628Cyclin-dependent kinase 22.7.11.220.495
3qziX72Cyclin-dependent kinase 22.7.11.220.495
1dm2HMDCyclin-dependent kinase 22.7.11.220.494
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.494
2pmlANPUncharacterized protein/0.494
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.494
3pj8404Cyclin-dependent kinase 22.7.11.220.493
3qrtX14Cyclin-dependent kinase 22.7.11.220.493
3r7eX88Cyclin-dependent kinase 22.7.11.220.493
3r8vZ62Cyclin-dependent kinase 22.7.11.220.493
3s00Z60Cyclin-dependent kinase 22.7.11.220.493
2r3lSCWCyclin-dependent kinase 22.7.11.220.492
3rahO1ZCyclin-dependent kinase 22.7.11.220.492
3unj0BXCyclin-dependent kinase 22.7.11.220.492
1oitHDTCyclin-dependent kinase 22.7.11.220.491
3lfqA28Cyclin-dependent kinase 22.7.11.220.491
3r1yX76Cyclin-dependent kinase 22.7.11.220.490
3ti1B49Cyclin-dependent kinase 22.7.11.220.490
5e8xSTUTGF-beta receptor type-12.7.11.300.490
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.489
4fkt48KCyclin-dependent kinase 22.7.11.220.489
1aq1STUCyclin-dependent kinase 22.7.11.220.488
1ckpPVBCyclin-dependent kinase 22.7.11.220.488
1ke8LS4Cyclin-dependent kinase 22.7.11.220.488
2vv9IM9Cyclin-dependent kinase 22.7.11.220.488
3at4CCKCasein kinase II subunit alpha2.7.11.10.488
3r28XA0Cyclin-dependent kinase 22.7.11.220.488
3s2pPMUCyclin-dependent kinase 22.7.11.220.488
4bcqTJFCyclin-dependent kinase 22.7.11.220.488
4bgg844Activin receptor type-12.7.11.300.488
4qmpDKISerine/threonine-protein kinase 242.7.11.10.488
3r8uZ31Cyclin-dependent kinase 22.7.11.220.487
3tiz3TICyclin-dependent kinase 22.7.11.220.487
4fkj11KCyclin-dependent kinase 22.7.11.220.487
5av2KMPDeath-associated protein kinase 12.7.11.10.487
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.486
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.486
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.486
1gii1PUCyclin-dependent kinase 22.7.11.220.485
2a4lRRCCyclin-dependent kinase 22.7.11.220.485
2c69CT8Cyclin-dependent kinase 22.7.11.220.485
3axwTIDCasein kinase II subunit alpha2.7.11.10.485
1fvv107Cyclin-dependent kinase 22.7.11.220.484
1ke5LS1Cyclin-dependent kinase 22.7.11.220.484
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.484
1e1xNW1Cyclin-dependent kinase 22.7.11.220.483
2r3r6SCCyclin-dependent kinase 22.7.11.220.483
3r9nZ68Cyclin-dependent kinase 22.7.11.220.483
4cfnJYMCyclin-dependent kinase 22.7.11.220.483
1gih1PUCyclin-dependent kinase 22.7.11.220.482
1ke7LS3Cyclin-dependent kinase 22.7.11.220.482
2uzlC94Cyclin-dependent kinase 22.7.11.220.482
3qtxX43Cyclin-dependent kinase 22.7.11.220.482
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.482
1oiqHDUCyclin-dependent kinase 22.7.11.220.481
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.481
2pywADPMethylthioribose kinase2.7.1.1000.481
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.481
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.481
1pxlCK4Cyclin-dependent kinase 22.7.11.220.480
1qmzATPCyclin-dependent kinase 22.7.11.220.480
4ek610KCyclin-dependent kinase 22.7.11.220.480
4kd11QKCyclin-dependent kinase 22.7.11.220.480
1e1vCMGCyclin-dependent kinase 22.7.11.220.479
2bheBRYCyclin-dependent kinase 22.7.11.220.479
2uzbC75Cyclin-dependent kinase 22.7.11.220.479
3qtwX3ACyclin-dependent kinase 22.7.11.220.479
4eomATPCyclin-dependent kinase 22.7.11.220.479
5e92ANPTGF-beta receptor type-22.7.11.300.479
2vgoAD5Aurora kinase B-A2.7.11.10.478
3ezvEZVCyclin-dependent kinase 22.7.11.220.478
4fkg4CKCyclin-dependent kinase 22.7.11.220.478
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.478
5cu6ATPCasein kinase II subunit alpha2.7.11.10.478
2xnbY8LCyclin-dependent kinase 22.7.11.220.477
4nj32KDCyclin-dependent kinase 22.7.11.220.477
2wxvWXVCyclin-dependent kinase 22.7.11.220.476
3rzb02ZCyclin-dependent kinase 22.7.11.220.476
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
4fv9E71Mitogen-activated protein kinase 12.7.11.240.476
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.475
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.475
3nga3NGCasein kinase II subunit alpha2.7.11.10.475
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.475
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.475
1jklANPDeath-associated protein kinase 12.7.11.10.474
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.474
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.473
2r3jSCJCyclin-dependent kinase 22.7.11.220.473
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.473
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.20.473
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.473
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.473
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.472
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.472
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.472
3rkb12ZCyclin-dependent kinase 22.7.11.220.472
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
1unhIXMCyclin-dependent-like kinase 52.7.11.10.471
1v0pPVBCell division control protein 2 homolog2.7.11.220.471
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.471
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.471
1oirHDYCyclin-dependent kinase 22.7.11.220.470
4bcoT6QCyclin-dependent kinase 22.7.11.220.470
4btjATPTau-tubulin kinase 12.7.11.10.470
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.469
2xikJ60Serine/threonine-protein kinase 252.7.11.10.469
3bhtMFRCyclin-dependent kinase 22.7.11.220.469
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
3qtsX46Cyclin-dependent kinase 22.7.11.220.469
3r7uX96Cyclin-dependent kinase 22.7.11.220.469
4dgo0JWCasein kinase II subunit alpha2.7.11.10.469
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.468
2pvnP63Casein kinase II subunit alpha2.7.11.10.468
2r3o2SCCyclin-dependent kinase 22.7.11.220.468
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.468
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.468
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.468
4iirANPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.468
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.467
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.467
3pe2E1BCasein kinase II subunit alpha2.7.11.10.467
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.467
2j9mPY8Cyclin-dependent kinase 22.7.11.220.466
2r3fSC8Cyclin-dependent kinase 22.7.11.220.466
2zjwREFCasein kinase II subunit alpha2.7.11.10.466
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.466
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.466
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.466
4gu94GUFocal adhesion kinase 12.7.10.20.466
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.465
1pxoCK7Cyclin-dependent kinase 22.7.11.220.465
1vjy460TGF-beta receptor type-12.7.11.300.465
2r3kSCQCyclin-dependent kinase 22.7.11.220.465
3uli1N3Cyclin-dependent kinase 22.7.11.220.465
1cm8ANPMitogen-activated protein kinase 12/0.464
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.464
2r3gSC9Cyclin-dependent kinase 22.7.11.220.464
3zh8C58Protein kinase C iota type2.7.11.130.464
4dgnLU2Casein kinase II subunit alpha2.7.11.10.464
5aniES4Cyclin-dependent kinase 22.7.11.220.464
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
3ttjJBIMitogen-activated protein kinase 102.7.11.240.463
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
1jstATPCyclin-dependent kinase 22.7.11.220.462
2vttLZDCyclin-dependent kinase 22.7.11.220.462
3r9oZ71Cyclin-dependent kinase 22.7.11.220.462
3wblPDYCyclin-dependent kinase 22.7.11.220.462
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.462
4hge15VTyrosine-protein kinase JAK2/0.462
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.462
5auvAGIDeath-associated protein kinase 12.7.11.10.462
1y91CT9Cyclin-dependent kinase 22.7.11.220.461
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.461
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.461
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.461
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.461
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.461
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.461
1b39ATPCyclin-dependent kinase 22.7.11.220.460
2pz5ACPFibroblast growth factor receptor 2/0.460
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.460
3gubGUBDeath-associated protein kinase 12.7.11.10.460
3lltANPProtein serine/threonine kinase-1/0.460
3mb714ICasein kinase II subunit alpha2.7.11.10.460
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.460
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
5auwQUEDeath-associated protein kinase 12.7.11.10.460
5av4GENDeath-associated protein kinase 12.7.11.10.460
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.459
2c6tDT5Cyclin-dependent kinase 22.7.11.220.459
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.459
2f2cAP9Cyclin-dependent kinase 62.7.11.220.459
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.459
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.459
3nynSGVG protein-coupled receptor kinase 62.7.11.160.459
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.459
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
1xjdSTUProtein kinase C theta type2.7.11.130.458
2bhhRYUCyclin-dependent kinase 22.7.11.220.458
2wipP49Cyclin-dependent kinase 22.7.11.220.458
2wouZZFTGF-beta receptor type-12.7.11.300.458
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
3gu6ADPDeath-associated protein kinase 12.7.11.10.458
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4ivb1J5Tyrosine-protein kinase JAK1/0.458
2vtqLZACyclin-dependent kinase 22.7.11.220.457
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.457
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.457
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.457
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.457
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
1pxkCK3Cyclin-dependent kinase 22.7.11.220.456
3i60E86Mitogen-activated protein kinase 12.7.11.240.456
3r9hZ67Cyclin-dependent kinase 22.7.11.220.456
3zewSTUEphrin type-B receptor 42.7.10.10.456
4grb0XGCasein kinase II subunit alpha2.7.11.10.456
4j97ACPFibroblast growth factor receptor 2/0.456
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.456
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.455
1zys199Serine/threonine-protein kinase Chk12.7.11.10.455
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.455
2j0j4STFocal adhesion kinase 12.7.10.20.455
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.455
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.455
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.455
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.455
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.455
4hvh19RTyrosine-protein kinase JAK32.7.10.20.455
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.455
5e8wSTUTGF-beta receptor type-12.7.11.300.455
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.454
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.454
2eufLQQCyclin-dependent kinase 62.7.11.220.454
2wotZZGTGF-beta receptor type-12.7.11.300.454
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.454
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.454
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.454
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.453
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.453
1unlRRCCyclin-dependent-like kinase 52.7.11.10.453
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.453
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3sheI85MAP kinase-activated protein kinase 32.7.11.10.453
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.453
4btjADPTau-tubulin kinase 12.7.11.10.453
4e200MYNon-receptor tyrosine-protein kinase TYK22.7.10.20.453
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.453
5av3KMPDeath-associated protein kinase 12.7.11.10.453
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.452
3r83Z14Cyclin-dependent kinase 22.7.11.220.452
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.452
3wowANPCasein kinase II subunit alpha2.7.11.10.452
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.452
5auzGENDeath-associated protein kinase 12.7.11.10.452
1b38ATPCyclin-dependent kinase 22.7.11.220.451
2c68CT6Cyclin-dependent kinase 22.7.11.220.451
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.451
3nup3NUCyclin-dependent kinase 62.7.11.220.451
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.451
3u4uLNHCasein kinase II subunit alpha2.7.11.10.451
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.451
4i22IREEpidermal growth factor receptor2.7.10.10.451
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.451
4ogrADNCyclin-dependent kinase 92.7.11.220.451
5cshATPCasein kinase II subunit alpha2.7.11.10.451
3gxlQIGTGF-beta receptor type-12.7.11.300.450
3zep1NXTyrosine-protein kinase JAK32.7.10.20.450
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.450
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.450
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.450
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.449
2c5yMTWCyclin-dependent kinase 22.7.11.220.449
3mb601ICasein kinase II subunit alpha2.7.11.10.449
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.449
3vryB43Tyrosine-protein kinase HCK2.7.10.20.449
4c02TAKActivin receptor type-12.7.11.300.449
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ivd15TTyrosine-protein kinase JAK1/0.449
1finATPCyclin-dependent kinase 22.7.11.220.448
1h0vUN4Cyclin-dependent kinase 22.7.11.220.448
2b53D23Cyclin-dependent kinase 22.7.11.220.448
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.448
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.448
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.448
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.448
4g170VNCasein kinase I isoform gamma-32.7.11.10.448
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.448
4gk2L66Ephrin type-A receptor 32.7.10.10.448
4gub0Y4Casein kinase II subunit alpha2.7.11.10.448
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.447
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3be9P04Casein kinase II subunit alpha2.7.11.10.447
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3zls92PDual specificity mitogen-activated protein kinase kinase 12.7.12.20.447
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.447
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4jrnANPRhoptry kinase family protein/0.447
4kba1QMCasein kinase I isoform delta2.7.11.10.447
4kbk1QGCasein kinase I isoform delta2.7.11.10.447
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.447
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.446
2hog710Serine/threonine-protein kinase Chk12.7.11.10.446
2r3q5SCCyclin-dependent kinase 22.7.11.220.446
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.446
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.446
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4hgt15GCasein kinase I isoform delta2.7.11.10.446
5auxKMPDeath-associated protein kinase 12.7.11.10.446
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.445
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.445
2excJNKMitogen-activated protein kinase 102.7.11.240.445
3bqr4RBDeath-associated protein kinase 3/0.445
3umw596Serine/threonine-protein kinase pim-12.7.11.10.445
4bhzZ0BDual specificity protein kinase TTK2.7.12.10.445
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.445
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
2pzpACPFibroblast growth factor receptor 2/0.444
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.444
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.444
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.444
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3qx4X4BCyclin-dependent kinase 22.7.11.220.444
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.444
4au8Z3RCyclin-dependent-like kinase 52.7.11.10.444
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.444
4riyADPEpidermal growth factor receptor2.7.10.10.444
1jpaANPEphrin type-B receptor 22.7.10.10.443
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.443
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.443
2h96893Mitogen-activated protein kinase 82.7.11.240.443
2xngA0HAurora kinase A2.7.11.10.443
4ek816KCyclin-dependent kinase 22.7.11.220.443
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.443
5aaaVGHALK tyrosine kinase receptor2.7.10.10.443
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.442
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.442
2uznC96Cyclin-dependent kinase 22.7.11.220.442
2zdt46CMitogen-activated protein kinase 102.7.11.240.442
3pe13NGCasein kinase II subunit alpha2.7.11.10.442
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.442
4c4h7RODual specificity protein kinase TTK2.7.12.10.442
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.442
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.441
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.441
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.441
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.441
2uzeC95Cyclin-dependent kinase 22.7.11.220.441
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3owk18ECasein kinase II subunit alpha2.7.11.10.441
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.441
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.441
4kb81QNCasein kinase I isoform delta2.7.11.10.441
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.441
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1zrzBI1Protein kinase C iota type2.7.11.130.440
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.440
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.440
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.440
2itnANPEpidermal growth factor receptor2.7.10.10.440
2izrBRKCasein kinase I isoform gamma-32.7.11.10.440
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.440
2vagV25Dual specificity protein kinase CLK12.7.12.10.440
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.440
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.440
2zdu446Mitogen-activated protein kinase 102.7.11.240.440
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.440
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.440
5dr6SKEAurora kinase A2.7.11.10.440