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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ek816KCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4ek816KCyclin-dependent kinase 22.7.11.221.000
2r3jSCJCyclin-dependent kinase 22.7.11.220.562
1oirHDYCyclin-dependent kinase 22.7.11.220.538
1oitHDTCyclin-dependent kinase 22.7.11.220.524
1y91CT9Cyclin-dependent kinase 22.7.11.220.523
2btrU73Cyclin-dependent kinase 22.7.11.220.520
3lfqA28Cyclin-dependent kinase 22.7.11.220.512
3lfnA27Cyclin-dependent kinase 22.7.11.220.511
4fkv61KCyclin-dependent kinase 22.7.11.220.511
3iggEFQCyclin-dependent kinase 22.7.11.220.505
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.504
3r1yX76Cyclin-dependent kinase 22.7.11.220.504
4ek610KCyclin-dependent kinase 22.7.11.220.501
1e1xNW1Cyclin-dependent kinase 22.7.11.220.497
2xmyCDKCyclin-dependent kinase 22.7.11.220.495
4fkg4CKCyclin-dependent kinase 22.7.11.220.495
4fks46KCyclin-dependent kinase 22.7.11.220.491
3qu0X40Cyclin-dependent kinase 22.7.11.220.490
1ykr628Cyclin-dependent kinase 22.7.11.220.486
2c6o4SPCyclin-dependent kinase 22.7.11.220.485
4fklCK2Cyclin-dependent kinase 22.7.11.220.485
2a0cCK9Cyclin-dependent kinase 22.7.11.220.483
4fkq42KCyclin-dependent kinase 22.7.11.220.477
3sw418KCyclin-dependent kinase 22.7.11.220.476
4fkt48KCyclin-dependent kinase 22.7.11.220.476
4fkpLS5Cyclin-dependent kinase 22.7.11.220.475
3rm618ZCyclin-dependent kinase 22.7.11.220.474
1aq1STUCyclin-dependent kinase 22.7.11.220.473
3rpv26ZCyclin-dependent kinase 22.7.11.220.473
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.471
2r3iSCFCyclin-dependent kinase 22.7.11.220.470
1pxlCK4Cyclin-dependent kinase 22.7.11.220.467
3rk909ZCyclin-dependent kinase 22.7.11.220.467
1w8cN69Cyclin-dependent kinase 22.7.11.220.466
3r8pZ46Cyclin-dependent kinase 22.7.11.220.463
2a4lRRCCyclin-dependent kinase 22.7.11.220.462
2vtsLZCCyclin-dependent kinase 22.7.11.220.462
3qtxX43Cyclin-dependent kinase 22.7.11.220.462
3r83Z14Cyclin-dependent kinase 22.7.11.220.462
4acm7YGCyclin-dependent kinase 22.7.11.220.461
3r71X86Cyclin-dependent kinase 22.7.11.220.460
1pxmCK5Cyclin-dependent kinase 22.7.11.220.457
2b52D42Cyclin-dependent kinase 22.7.11.220.455
1b38ATPCyclin-dependent kinase 22.7.11.220.453
3r7yZ04Cyclin-dependent kinase 22.7.11.220.453
3rk708ZCyclin-dependent kinase 22.7.11.220.453
2r3q5SCCyclin-dependent kinase 22.7.11.220.451
3rni21ZCyclin-dependent kinase 22.7.11.220.451
1ke5LS1Cyclin-dependent kinase 22.7.11.220.450
3r8lZ30Cyclin-dependent kinase 22.7.11.220.449
4fki09KCyclin-dependent kinase 22.7.11.220.449
1pxoCK7Cyclin-dependent kinase 22.7.11.220.448
2r3kSCQCyclin-dependent kinase 22.7.11.220.447
3qwjX6ACyclin-dependent kinase 22.7.11.220.447
4kd11QKCyclin-dependent kinase 22.7.11.220.445
2r3p3SCCyclin-dependent kinase 22.7.11.220.444
3rjc06ZCyclin-dependent kinase 22.7.11.220.444
1h0w207Cyclin-dependent kinase 22.7.11.220.443
4bgh3I6Cyclin-dependent kinase 22.7.11.220.442
2uznC96Cyclin-dependent kinase 22.7.11.220.441
3rpo24ZCyclin-dependent kinase 22.7.11.220.441
1y8yCT7Cyclin-dependent kinase 22.7.11.220.440