Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ea2RWZDehydrosqualene synthase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4ea2RWZDehydrosqualene synthase/1.000
2zcqB65Dehydrosqualene synthase/0.557
4f6vZYMDehydrosqualene synthase/0.542
3acw651Dehydrosqualene synthase/0.515
4ea0651Dehydrosqualene synthase/0.502
4ea13RXDehydrosqualene synthase/0.474
3tfn2CJDehydrosqualene synthase/0.465