sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ea1 | 3RX | Dehydrosqualene synthase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 1.000 | |
| 2zcq | B65 | Dehydrosqualene synthase | / | 0.610 | |
| 3tfn | 2CJ | Dehydrosqualene synthase | / | 0.609 | |
| 3acy | 702 | Dehydrosqualene synthase | / | 0.608 | |
| 4ea0 | 651 | Dehydrosqualene synthase | / | 0.585 | |
| 3tfp | 03L | Dehydrosqualene synthase | / | 0.571 | |
| 4f6v | ZYM | Dehydrosqualene synthase | / | 0.566 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.543 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.528 | |
| 4f6x | ZYL | Dehydrosqualene synthase | / | 0.456 | |
| 2bxo | OPB | Serum albumin | / | 0.453 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.442 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.440 |